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All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Page: 1 2 3 4 5 6...14 Hits 21 – 40 of 265 21 Common mental disorders and patient-reported swallowing disorders following total laryngectomy Emykaelly Kauanne Lima Batista; Jaims Franklin Ribeiro Soares; Giorvan Anderson dos Santos Alves... In: Revista CEFAC, Vol 23, Iss 6 (2021) (2021) BASE Show details 22 Expressive language development in adolescents with Down syndrome and fragile X syndrome: change over time and the role of family-related factors. Del Hoyo Soriano, Laura; Thurman, Angela John; Harvey, Danielle... In: Journal of neurodevelopmental disorders, vol 12, iss 1 (2020) BASE Show details 23 Depressive Symptom Profiles Predict Specific Neurodegenerative Disease Syndromes in Early Stages. Shdo, Suzanne M; Ranasinghe, Kamalini G; Sturm, Virginia E. - : eScholarship, University of California, 2020 BASE Show details 24 Utility of the global CDR® plus NACC FTLD rating and development of scoring rules: Data from the ARTFL/LEFFTDS Consortium. Miyagawa, Toji; Brushaber, Danielle; Syrjanen, Jeremy... In: Alzheimer's & dementia : the journal of the Alzheimer's Association, vol 16, iss 1 (2020) BASE Show details 25 Use of the CDR® plus NACC FTLD in mild FTLD: Data from the ARTFL/LEFFTDS consortium. Miyagawa, Toji; Brushaber, Danielle; Syrjanen, Jeremy... In: Alzheimer's & dementia : the journal of the Alzheimer's Association, vol 16, iss 1 (2020) BASE Show details 26 Depressive Symptom Profiles Predict Specific Neurodegenerative Disease Syndromes in Early Stages. Shdo, Suzanne M; Ranasinghe, Kamalini G; Sturm, Virginia E. - : eScholarship, University of California, 2020 BASE Show details 27 Utility of the global CDR® plus NACC FTLD rating and development of scoring rules: Data from the ARTFL/LEFFTDS Consortium. Miyagawa, Toji; Brushaber, Danielle; Syrjanen, Jeremy... In: Alzheimer's & dementia : the journal of the Alzheimer's Association, vol 16, iss 1 (2020) BASE Show details 28 Use of the CDR® plus NACC FTLD in mild FTLD: Data from the ARTFL/LEFFTDS consortium. Miyagawa, Toji; Brushaber, Danielle; Syrjanen, Jeremy... In: Alzheimer's & dementia : the journal of the Alzheimer's Association, vol 16, iss 1 (2020) BASE Show details 29 A neurophysiological model of speech production deficits in fragile X syndrome. Schmitt, Lauren M; Wang, Jun; Pedapati, Ernest V... In: Brain communications, vol 2, iss 1 (2020) BASE Show details 30 Screen time in 36-month-olds at increased likelihood for ASD and ADHD. Hill, Monique Moore; Gangi, Devon; Miller, Meghan. - : eScholarship, University of California, 2020 BASE Show details 31 Screen time in 36-month-olds at increased likelihood for ASD and ADHD. Hill, Monique Moore; Gangi, Devon; Miller, Meghan. - : eScholarship, University of California, 2020 BASE Show details 32 Molecular Biomarkers Predictive of Sertraline Treatment Response in Young Children With Autism Spectrum Disorder. Alolaby, Reem Rafik; Jiraanont, Poonnada; Durbin-Johnson, Blythe; Jasoliya, Mittal; Tang, Hiu-Tung; Hagerman, Randi; Tassone, Flora. - : eScholarship, University of California, 2020 Abstract: Sertraline is one among several selective serotonin reuptake inhibitors (SSRIs) that exhibited improvement of language development in Autism Spectrum Disorder (ASD); however, the molecular mechanism has not been elucidated. A double blind, randomized, 6-month, placebo-controlled, clinical trial of low-dose sertraline in children ages (3-6 years) with ASD was conducted at the UC Davis MIND Institute. It aimed at evaluating the efficacy and benefit with respect to early expressive language development and global clinical improvement. This study aimed to identify molecular biomarkers that might be key players in the serotonin pathway and might be predictive of a clinical response to sertraline. Fifty eight subjects with the diagnosis of ASD were randomized to sertraline or placebo. Eight subjects from the sertraline arm and five from the placebo arm discontinued from the study. Furthermore, four subjects did not have a successful blood draw. Hence, genotypes for 41 subjects (20 on placebo and 21 on sertraline) were determined for several genes involved in the serotonin pathway including the serotonin transporter-linked polymorphic region (5-HTTLPR), the tryptophan hydroxylase 2 (TPH2), and the Brain-Derived Neurotrophic Factor (BDNF). In addition, plasma levels of BDNF, Matrix metallopeptidase 9 (MMP-9) and a selected panel of cytokines were determined at baseline and post-treatment. Intent-to-treat analysis revealed several primary significant correlations between molecular changes and the Mullen Scales of Early Learning (MSEL) and Clinical Global Impression Scale - Improvement (CGI-I) of treatment and control groups but they were not significant after adjustment for multiple testing. Thus, sertraline showed no benefit for treatment of young children with ASD in language development or changes in molecular markers in this study. These results indicate that sertraline may not be beneficial for the treatment of children with ASD; however, further investigation of larger groups as well as longer term follow-up studies are warranted. Keyword: 6.1 Pharmaceuticals; Autism; Autism Spectrum Disorders; Brain Disorders; Clinical Research; Clinical Sciences; Clinical Trials and Supportive Activities; Genetics; Intellectual and Developmental Disabilities (IDD); Law; Mental Health; molecular biomarkers; Neurosciences; Pediatric; Prevention; selective serotonin reuptake inhibitor; serotonin; sertraline URL: https://escholarship.org/uc/item/3n6774pz BASE Hide details 33 A Therapeutic Relational Agent for Reducing Problematic Substance Use (Woebot): Development and Usability Study (Preprint) Prochaska, Judith J; Vogel, Erin A; Chieng, Amy. - : eScholarship, University of California, 2020 BASE Show details 34 The Relationship between Expressive Language Sampling and Clinical Measures in Fragile X Syndrome and Typical Development. Shaffer, Rebecca C; Schmitt, Lauren; John Thurman, Angela... In: Brain sciences, vol 10, iss 2 (2020) BASE Show details 35 Artificial intelligence approaches to predicting and detecting cognitive decline in older adults: A conceptual review. Graham, Sarah A; Lee, Ellen E; Jeste, Dilip V. - : eScholarship, University of California, 2020 BASE Show details 36 Contributions of common genetic variants to risk of schizophrenia among individuals of African and Latino ancestry. Bigdeli, Tim B; Genovese, Giulio; Georgakopoulos, Penelope... In: Molecular psychiatry, vol 25, iss 10 (2020) BASE Show details 37 Contributions of common genetic variants to risk of schizophrenia among individuals of African and Latino ancestry. Bigdeli, Tim B; Genovese, Giulio; Georgakopoulos, Penelope... In: Molecular psychiatry, vol 25, iss 10 (2020) BASE Show details 38 Health comorbidities and cognitive abilities across the lifespan in Down syndrome. ... Startin, Carla M; D'Souza, Hana; Ball, George. - : Apollo - University of Cambridge Repository, 2020 BASE Show details 39 Клинико-лингвистические характеристики психических нарушений при ВИЧ-инфицировании ... : Clinical and linguistic characteristics of mental disorders in HIV infection ... Khalezova, Nadezhda; Piotrowska, Xenia; Terbusheva, Ekaterina. - : Society. Communication. Education, 2020 BASE Show details 40 Assessing Health Related Quality of Life, Language Impairment, and Psychosocial Factors in Post-Stroke Aphasia Palangas, Sophia M.E. In: Honors College (2020) BASE Show details Page: 1 2 3 4 5 6...14

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