1 |
Influence of age and schooling in written discourse of healthy adults
|
|
|
|
In: Psicol Reflex Crit (2020)
|
|
BASE
|
|
Show details
|
|
2 |
Narrative impairment, white matter damage and CSF biomarkers in the Alzheimer’s disease spectrum
|
|
Drummond, Claudia; Coutinho, Gabriel; Monteiro, Marina Carneiro; Assuncao, Naima; Teldeschi, Alina; de Souza, Andrea Silveira; Oliveira, Natalia; Bramati, Ivanei; Sudo, Felipe Kenji; Vanderboght, Bart; Brandao, Carlos Otavio; Fonseca, Rochele Paz; de Oliveira-Souza, Ricardo; Moll, Jorge; Mattos, Paulo; Tovar-Moll, Fernanda. - : Impact Journals, 2019
|
|
Abstract:
Background: Narrative discourse (ND) refers to one’s ability to verbally reproduce a sequence of temporally and logically-linked events. Impairments in ND may occur in subjects with Amnestic Mild Cognitive Impairment (aMCI) and Alzheimer’s Disease (AD), but correlates across this function, neuroimaging and cerebrospinal fluid (CSF) AD biomarkers remain understudied. Objectives: We sought to measure correlates among ND, Diffusion Tensor Imaging (DTI) indexes and AD CSF biomarkers in patients within the AD spectrum. Results: Groups differed in narrative production (NProd) and comprehension. aMCI and AD presented poorer inference abilities than controls. AD subjects were more impaired than controls and aMCI regarding WB (p<0.01). ROIs DTI assessment distinguished the three groups. Mean Diffusivity (MD) in the uncinate, bilateral parahippocampal cingulate and left inferior occipitofrontal fasciculi negatively correlated with NProd. Changes in specific tracts correlated with T-tau/Aβ1-42 ratio in CSF. Conclusions: AD and aMCI patients presented more ND impairments than controls. Those findings were associated with changes in ventral language-associated and in the inferior parahippocampal pathways. The latest were correlated with biomarkers’ levels in the CSF. Methods: AD (N=14), aMCI (N=31) and Control (N=39) groups were compared for whole brain (WB) and regions of interest (ROI) DTI parameters, ND and AD CSF biomarkers.
|
|
Keyword:
Research Paper
|
|
URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834410/ https://doi.org/10.18632/aging.102391 http://www.ncbi.nlm.nih.gov/pubmed/31682234
|
|
BASE
|
|
Hide details
|
|
3 |
Age-related differences in conversational discourse abilities A comparative study
|
|
|
|
BASE
|
|
Show details
|
|
4 |
Reading Aloud and Child Development: A Cluster-Randomized Trial in Brazil
|
|
|
|
BASE
|
|
Show details
|
|
5 |
Processamento discursivo e executivo pós-traumatismo cranioencefálico
|
|
Pereira, Natalie. - : Pontifícia Universidade Católica do Rio Grande do Sul, 2015. : Porto Alegre, 2015
|
|
BASE
|
|
Show details
|
|
6 |
Deficits in narrative discourse elicited by visual stimuli are already present in patients with mild cognitive impairment
|
|
|
|
BASE
|
|
Show details
|
|
9 |
Processamentos linguístico, perceptivo auditivo e executivo em crianças: o papel da idade, do tipo de escola e do TDAH
|
|
|
|
BASE
|
|
Show details
|
|
10 |
Evolution of language assessment in patients with acquired neurological disorders in Brazil
|
|
|
|
BASE
|
|
Show details
|
|
11 |
Rehabilitation of lexical and semantic communicative impairments: An overview of available approaches
|
|
|
|
BASE
|
|
Show details
|
|
12 |
Evidência de validade de construto do NEUPSILIN utilizando análise fatorial confirmatória
|
|
|
|
BASE
|
|
Show details
|
|
13 |
Perfis comunicativos e desenvolvimento de tarefas para reabilitação discursiva pós-acidente vascular cerebral unilateral
|
|
Gindri, Gigiane. - : Pontifícia Universidade Católica do Rio Grande do Sul, 2013. : Porto Alegre, 2013
|
|
BASE
|
|
Show details
|
|
14 |
Bateria montreal-toulouse de avaliação da linguagem: evidências de validade e de fidedignidade com adultos saudáveis e com lesão cerebral unilateral com e sem afasia
|
|
|
|
BASE
|
|
Show details
|
|
15 |
Adaptação da Bateria Montreal de Avaliação da Comunicação : versão brasileira MAC-BR para o português europeu
|
|
|
|
BASE
|
|
Show details
|
|
16 |
Avaliação neuropsicológica de funções executivas em adultos após traumatismo cranioencefálico : ênfase no componente planejamento
|
|
|
|
BASE
|
|
Show details
|
|
20 |
Comunicação em adultos com lesão vascular de hemisfério direito: dados clínicos com bateria breve, neuroimagem e implicações para reabilitação neuropsicológica comportamental
|
|
|
|
BASE
|
|
Show details
|
|
|
|