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1
Dominant hemisphere functional networks compensate for structural connectivity loss to preserve phonological retrieval with aging
Agarwal, Smriti; Stamatakis, Emmanuel A.; Geva, Sharon. - : John Wiley and Sons Inc., 2016
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2
Optimally Efficient Neural Systems for Processing Spoken Language
Zhuang, Jie; Tyler, Lorraine K.; Randall, Billi. - : Oxford University Press, 2014
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3
Functional organisation of the neural language system: Dorsal and ventral pathways are critical for syntax
Abstract: The core of human language, which differentiates it from the communicative abilities of other species, is the set of combinatorial operations called syntax. For over a century researchers have attempted to understand how this essential function is organised in the brain. Here we combine behavioural and neuroimaging methods, with left hemisphere-damaged patients and healthy controls, to identify the pathways connecting the brain regions involved in syntactic processing. In a previous fMRI study (Tyler et al. 2010b) we established that regions of left inferior frontal cortex and left posterior middle temporal cortex were activated during syntactic processing. These clusters were used here as seeds for probabilistic tractography analyses in patients and controls, allowing us to delineate, and measure the integrity of, the white matter tracts connecting the frontal and temporal regions active for syntax. We found that structural disconnection in either of two fibre bundles - the arcuate fasciculus or the extreme capsule fibre system - was associated with syntactic impairment in patients. The results demonstrate the causal role in syntactic analysis of these two major left hemisphere fibre bundles - challenging existing views about their role in language functions, and providing a new basis for future research in this key area of human cognition.
Keyword: Article
URL: https://doi.org/10.1093/cercor/bhr386
http://www.ncbi.nlm.nih.gov/pubmed/22275482
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601415
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4
Optimally Efficient Neural Systems for Processing Spoken Language
Zhuang, Jie; Tyler, Lorraine K.; Randall, Billi. - : Oxford University Press, 2012
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5
Age-related Neural Reorganization during Spoken Word Recognition: The Interaction of Form and Meaning
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6
Differentiating Hemispheric Contributions to Syntax and Semantics in Patients with Left-Hemisphere Lesions
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7
Dynamic Processing in the Human Language System: Synergy between the Arcuate Fascicle and Extreme Capsule
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8
Word retrieval failures in old age: the relationship between structure and function
In: Journal of cognitive neuroscience. - Cambridge, Mass. : MIT Press Journals 22 (2010) 7, 1530-1540
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9
Reorganization of syntactic processing following left-hemisphere brain damage: does right-hemisphere activity preserve function?
Tyler, Lorraine K.; Wright, Paul; Randall, Billi. - : Oxford University Press, 2010
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10
Reorganization of syntactic processing following left-hemisphere brain damage: does right-hemisphere activity preserve function?
Tyler, Lorraine K.; Wright, Paul; Randall, Billi. - : Oxford University Press, 2010
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11
Reorganization of syntactic processing following left-hemisphere brain damage: does right-hemisphere activity preserve function?
Tyler, Lorraine K.; Wright, Paul; Randall, Billi. - : Oxford University Press, 2010
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12
Cortical differentiation for nouns and verbs depends on grammatical markers
In: Journal of cognitive neuroscience. - Cambridge, Mass. : MIT Press Journals 20 (2008) 8, 1381-1389
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OLC Linguistik
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13
Longitudinal studies of semantic dementia: The relationship between structural and functional changes over time
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14
On the tip-of-the-tongue: neural correlates of increased word-finding failures in normal aging
In: Journal of cognitive neuroscience. - Cambridge, Mass. : MIT Press Journals 19 (2007) 12, 2060-2070
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OLC Linguistik
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15
Differentiating morphology, form, and meaning: neural correlates of morphological complexity
In: Journal of cognitive neuroscience. - Cambridge, Mass. : MIT Press Journals 19 (2007) 9, 1464-1475
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16
Temporal lobe lesions and semantic impairment: a comparison of herpes simplex virus encephalitis and semantic dementia
In: Brain. - Oxford : Oxford Univ. Press 130 (2007) 4, 1138-1147
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17
On the Tip-of-the-Tongue: Neural Correlates of Increased Word-finding Failures in Normal Aging
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18
Identifying lesions on structural brain images#8212Validation of the method and application to neuropsychological patients
In: Brain & language. - Orlando, Fla. [u.a.] : Elsevier 94 (2005) 2, 167-177
OLC Linguistik
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19
Identifying lesions on structural brain images : validation of the method and application to neuropsychological patients
In: Brain & language. - Orlando, Fla. [u.a.] : Elsevier 94 (2005) 2, 167-177
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20
Deficits for semantics and the irregular past tense : a causal relationship?
In: Journal of cognitive neuroscience. - Cambridge, Mass. : MIT Press Journals 16 (2004) 7, 1159-1172
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