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Toward a paradigm shift from deficit-based to proactive speech and language treatment: Randomized pilot trial of the Babble Boot Camp in infants with classic galactosemia
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Peter, Beate; Potter, Nancy; Davis, Jennifer; Donenfeld-Peled, Inbal; Finestack, Lizbeth; Stoel-Gammon, Carol; Lien, Kari; Bruce, Laurel; Vose, Caitlin; Eng, Linda; Yokoyama, Hanako; Olds, Daniel; VanDam, Mark
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In: F1000Res (2020)
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Abstract:
Background: Speech and language therapy is typically initiated reactively after a child starts showing delays. Infants with classic galactosemia (CG), a metabolic disease with a known high risk for both speech and language disorders, hold the keys towards evaluating whether preventive treatment is effective when the risks are known at birth. We present pilot data from a randomized parallel trial of an innovative proactive speech and language intervention program, the Babble Boot Camp (BBC). Method: Five children with CG, otherwise healthy, participated in the study from approximately 2 to 24 months of age. One of these was randomly selected as control receiving conventional management, which typically starts at age 2-3 years. A pediatric speech-language pathologist met weekly via telepractice with the parents in the treatment cohort. Parents implemented the prespeech, speech, and language stimulation and expansion activities according to the intervention protocol. The control child was still too young for conventional treatment. Primary outcome measures were speech sound production complexity in babble and speech and expressive vocabulary size. Secondary outcome measures were vocalization rates and developmental milestones in communication, motor, and cognition. The trial is ongoing. Results: All four treated children had higher speech sound skills in babble, three had higher speech sound skills in meaningful speech, two had higher expressive vocabularies, three had higher global developmental scores, and two had higher vocalization rates, compared to the control child with CG. Discussion: Given the high risk for speech and language delays in children with CG, finding on-schedule abilities in two or more of the treated children but not the untreated child is unexpected under random conditions. The trends toward beneficial effects of the BBC on speech sound production, expressive language, and communication milestones warrant appropriately powered larger clinical trials with full randomization. Trial registration: ClinicalTrials.gov NCT03838016 (12 (th) February 2019).
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Keyword:
Research Article
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URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291108/ https://doi.org/10.12688/f1000research.18062.3
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Toddler Talk: Findings from a Phonological Assessment Test that Uses “Early” Words
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In: ETSU Faculty Works (2017)
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Defining Spoken Language Benchmarks and Selecting Measures of Expressive Language Development for Young Children With Autism Spectrum Disorders
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Identification of Speech-language Disorders in Toddlers
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In: ETSU Faculty Works (2016)
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Using PhonBank and Phon in Studies of Phonological Development and Disorders
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Acquisition of Obstruents in Children with Cleft Palate: Evidence from an Intervention Study
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In: ETSU Faculty Works (2014)
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Early Phonological Development: Creating an Assessment Test
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In: ETSU Faculty Works (2013)
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Associations among measures of sequential processing in motor and linguistics tasks in adults with and without a family history of childhood apraxia of speech: A replication study
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Deficits in sequential processing manifest in motor and linguistic tasks in a multigenerational family with childhood apraxia of speech
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Tables Showing Target Words for Lexical and Phonological Effects in Early Word Production (Sosa and Stoel-Gammon, 2012) ...
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Tables Showing Target Words for Lexical and Phonological Effects in Early Word Production (Sosa and Stoel-Gammon, 2012) ...
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Assessment of Single-Word Production for Children under Three Years of Age: Comparison of Children with and without Cleft Palate
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In: ETSU Faculty Works (2012)
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Efficacy of an Early Speech Intervention for Children with Cleft Palate
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In: ETSU Faculty Works (2012)
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Early Phonological Development: Creating an Assessment Test
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In: ETSU Faculty Works (2012)
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Assessment of Single-Word Production for Children under Three Years of Age: Comparison of Children with and without Cleft Palate
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