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The Contribution of Working Memory Areas to Verbal Learning and Recall in Primary Progressive Aphasia
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In: Front Neurol (2022)
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Sonorant spectra and coarticulation distinguish speakers with different dialects ...
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Effects of tDCS on Sound Duration in Patients with Apraxia of Speech in Primary Progressive Aphasia
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In: Brain Sci (2021)
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A Systematic Review of Transcranial Direct Current Stimulation in Primary Progressive Aphasia: Methodological Considerations
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In: Front Aging Neurosci (2021)
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Selective Functional Network Changes Following tDCS-Augmented Language Treatment in Primary Progressive Aphasia
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In: Front Aging Neurosci (2021)
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Part of Speech Production in Patients With Primary Progressive Aphasia: An Analysis Based on Natural Language Processing
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In: Am J Speech Lang Pathol (2021)
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A Tool for Automatic Scoring of Spelling Performance
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In: J Speech Lang Hear Res (2020)
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White Matter Hyperintensities Contribute to Language Deficits in Primary Progressive Aphasia
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In: Cogn Behav Neurol (2020)
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Different patterns of functional network re-organization across the variants of primary progressive aphasia: A graph theoretic analysis
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In: Neurobiol Aging (2020)
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Effects of executive attention on sentence processing in aphasia
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In: Aphasiology (2019)
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The use of spelling for variant classification in primary progressive aphasia: Theoretical and practical implications
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In: Neuropsychologia (2019)
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The Role of Word Properties in Performance on Fluency Tasks in People with Primary Progressive Aphasia
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“The effect of tDCS on functional connectivity in primary progressive aphasia” NeuroImage: Clinical, volume 19 (2018), pages 703–715
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Written Verb Naming Improves After tDCS Over the Left IFG in Primary Progressive Aphasia
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The Role of Language Severity and Education in Explaining Performance on Object and Action Naming in Primary Progressive Aphasia
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Abstract:
Despite the common assumption that atrophy in a certain brain area would compromise the function that it subserves, this is not always the case, especially in complex clinical syndromes such as primary progressive aphasia (PPA). Clinical and demographic information may contribute to PPA phenotypes and explain the manifested impairments better than atrophy. In the present study, we asked how much variance of the object and action naming impairments observed in PPA may be attributed to atrophy in the language network alone vs. additional clinical and demographic factors including language severity and education. Thirty-nine participants with PPA underwent magnetic resonance imaging (MRI) for volumetric analysis and a complete neuropsychological examination, including standardized tests of object and action naming. We used stepwise regression models to compare atrophy (volumetric model) to clinical/demographic variables (clinical-demographic model) for naming objects and actions. The clinical-demographic model was the best-fit model that explained the largest amount of variance in both object and action naming. Brain volume measurements alone explained little variance in both object and action naming. Clinical factors, particularly language severity, and demographic factors, particularly education, need to be considered in conjunction with brain volumes in PPA. The present study emphasizes the complexity of PPA as a syndrome and provides an example of how volumetric, clinical and demographic factors may interact in determining naming performance/deterioration.
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Keyword:
Neuroscience
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URL: https://doi.org/10.3389/fnagi.2018.00346 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218435/ http://www.ncbi.nlm.nih.gov/pubmed/30425638
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Cerebellar tDCS: A Novel Approach to Augment Language Treatment Post-stroke
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Transcranial Direct Current Stimulation in Post Stroke Aphasia and Primary Progressive Aphasia: Current Knowledge and Future Clinical Applications
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