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Conceptual framework for the definition of preclinical and prodromal frontotemporal dementia. ...
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Language training for oral and written naming impairment in primary progressive aphasia: a review
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In: Transl Neurodegener (2021)
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Conceptual framework for the definition of preclinical and prodromal frontotemporal dementia.
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Benussi, Alberto; Alberici, Antonella; Samra, Kiran; Russell, Lucy L; Greaves, Caroline V; Bocchetta, Martina; Ducharme, Simon; Finger, Elizabeth; Fumagalli, Giorgio; Galimberti, Daniela; Jiskoot, Lize C; Le Ber, Isabelle; Masellis, Mario; Nacmias, Benedetta; Rowe, James; Sanchez-Valle, Raquel; Seelaar, Harro; Synofzik, Matthis; GENFI Consortium; Rohrer, Jonathan D; Borroni, Barbara. - : Wiley, 2021. : Department of Clinical Neurosciences, 2021. : Alzheimers Dement, 2021
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Abstract:
The presymptomatic stages of frontotemporal dementia (FTD) are still poorly defined and encompass a long accrual of progressive biological (preclinical) and then clinical (prodromal) changes, antedating the onset of dementia. The heterogeneity of clinical presentations and the different neuropathological phenotypes have prevented a prior clear description of either preclinical or prodromal FTD. Recent advances in therapeutic approaches, at least in monogenic disease, demand a proper definition of these predementia stages. It has become clear that a consensus lexicon is needed to comprehensively describe the stages that anticipate dementia. The goal of the present work is to review existing literature on the preclinical and prodromal phases of FTD, providing recommendations to address the unmet questions, therefore laying out a strategy for operationalizing and better characterizing these presymptomatic disease stages.
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Keyword:
definition; frontotemporal dementia; frontotemporal lobar degeneration; mild cognitive and/or behavioral and/or motor impairment; mild cognitive impairment; preclinical; presymptomatic; prodromal
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URL: https://doi.org/10.17863/CAM.79392 https://www.repository.cam.ac.uk/handle/1810/331943
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Modelling the cascade of biomarker changes in GRN-related frontotemporal dementia
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In: J Neurol Neurosurg Psychiatry (2021)
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C9orf72, age at onset, and ancestry help discriminate behavioral from language variants in FTLD cohorts.
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In: Neurology, vol 95, iss 24 (2020)
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C9orf72, age at onset, and ancestry help discriminate behavioral from language variants in FTLD cohorts
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C9orf72, age at onset, and ancestry help discriminate behavioral from language variants in FTLD cohorts
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In: Neurology (2020)
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C9orf72, age at onset, and ancestry help discriminate behavioral from language variants in FTLD cohorts
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The role of the motor system in action naming in patients with neurodegenerative extrapyramidal syndromes
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Grey Matter Density Predicts the Improvement of Naming Abilities After tDCS Intervention in Agrammatic Variant of Primary Progressive Aphasia
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Anodal transcranial direct current stimulation of parietal cortex enhances action naming in corticobasal syndrome
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Understanding Emotions in Frontotemporal Dementia: The Explicit and Implicit Emotional Cue Mismatch
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Balconi, Michela (orcid:0000-0002-8634-1951); Cotelli, Maria; Brambilla, Michela. - : IOS Press:Nieuwe Hemweg 6B, 1013 BG Amsterdam Netherlands:011 31 20 6883355, EMAIL: r.tosendjojo@iospress.nl, INTERNET: http://www.iospress.nl, Fax: 011 31 20 6203419, 2015
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Anodal transcranial direct current stimulation of parietal cortex enhances action naming in Corticobasal Syndrome
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Right Hemisphere Involvement in Non-Fluent Primary Progressive Aphasia
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