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All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Hits 1 – 12 of 12 1 Cooking from cold to hot: goal-directedness in simulation and language Welke, Tinka [Verfasser]; Raisig, Susanne [Verfasser]; Nowack, Kati [Verfasser]. - Berlin : Humboldt-Universität zu Berlin, 2021 DNB Subject Category Language Show details 2 Associated functional network development and language abilities in children ... Qi, Ting; Schaadt, Gesa; Friederici, Angela D.. - : Freie Universität Berlin, 2021 BASE Show details 3 Associated functional network development and language abilities in children Qi, Ting; Schaadt, Gesa; Friederici, Angela D. In: Neuroimage (2021) BASE Show details 4 Aberrant Prestimulus Oscillations in Developmental Dyslexia Support an Underlying Attention Shifting Deficit Meyer, Lars; Schaadt, Gesa In: Cereb Cortex Commun (2020) BASE Show details 5 Cortical thickness lateralization and its relation to language abilities in children Qi, Ting; Schaadt, Gesa; Friederici, Angela D.. - : Elsevier, 2019 BASE Show details 6 Dyslexia risk gene relates to representation of sound in the auditory brainstem Neef, Nicole E.; Müller, Bent; Liebig, Johanna. - : Elsevier, 2017 BASE Show details 7 Dyslexia risk gene relates to representation of sound in the auditory brainstem Neef, Nicole E.; Müller, Bent; Liebig, Johanna. - : Elsevier, 2017 BASE Show details 8 ATP2C2 and DYX1C1 are putative modulators of dyslexia-related MMR Müller, Bent; Schaadt, Gesa; Boltze, Johannes; Emmrich, Frank; Skeide, Michael A.; Neef, Nicole E.; Kraft, Indra; Brauer, Jens; Friederici, Angela D.; Kirsten, Holger; Wilcke, Arndt. - : John Wiley & Sons Ltd., 2017 Abstract: Background Dyslexia is a specific learning disorder affecting reading and spelling abilities. Its prevalence is ~5% in German‐speaking individuals. Although the etiology of dyslexia largely remains to be determined, comprehensive evidence supports deficient phonological processing as a major contributing factor. An important prerequisite for phonological processing is auditory discrimination and, thus, essential for acquiring reading and spelling skills. The event‐related potential Mismatch Response (MMR) is an indicator for auditory discrimination capabilities with dyslexics showing an altered late component of MMR in response to auditory input. Methods In this study, we comprehensively analyzed associations of dyslexia‐specific late MMRs with genetic variants previously reported to be associated with dyslexia‐related phenotypes in multiple studies comprising 25 independent single‐nucleotide polymorphisms (SNPs) within 10 genes. Results First, we demonstrated validity of these SNPs for dyslexia in our sample by showing that additional inclusion of a polygenic risk score improved prediction of impaired writing compared with a model that used MMR alone. Secondly, a multifactorial regression analysis was conducted to uncover the subset of the 25 SNPs that is associated with the dyslexia‐specific late component of MMR. In total, four independent SNPs within DYX1C1 and ATP2C2 were found to be associated with MMR stronger than expected from multiple testing. To explore potential pathomechanisms, we annotated these variants with functional data including tissue‐specific expression analysis and eQTLs. Conclusion Our findings corroborate the late component of MMR as a potential endophenotype for dyslexia and support tripartite relationships between dyslexia‐related SNPs, the late component of MMR and dyslexia. Keyword: RC Internal medicine URL: http://wrap.warwick.ac.uk/118687/1/WRAP-ATP2C2-DYX1C1-putative-modulators-dyslexia-related-MMR-Boltze-2017.pdf https://doi.org/10.1002/brb3.851 http://wrap.warwick.ac.uk/118687/ BASE Hide details 9 Phonological abilities in literacy-impaired children: Brain potentials reveal deficient phoneme discrimination, but intact prosodic processing Männel, Claudia; Schaadt, Gesa; Illner, Franziska K.. - : Elsevier, 2016 BASE Show details 10 Genetic dyslexia risk variant is related to neural connectivity patterns underlying phonological awareness in children Skeide, Michael A.; Kirsten, Holger; Kraft, Indra. - : Elsevier, 2015 BASE Show details 11 Cooking from cold to hot: goal-directedness in simulation and language Welke, Tinka; Raisig, Susanne; Nowack, Kati. - : Humboldt-Universität zu Berlin, 2014 BASE Show details 12 Impact of phonological processing skills on written language acquisition in illiterate adults Landgraf, Steffen; Beyer, Reinhard; Hild, Isabella. - : Elsevier, 2011 BASE Show details

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