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Development of a standard of care for patients with valosin-containing protein associated multisystem proteinopathy.
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In: Orphanet journal of rare diseases, vol 17, iss 1 (2022)
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| 2 |
Family history of FXTAS is associated with age-related cognitive-linguistic decline among mothers with the FMR1 premutation.
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In: Journal of neurodevelopmental disorders, vol 14, iss 1 (2022)
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Cortical microstructure in primary progressive aphasia: a multicenter study.
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In: Alzheimer's research & therapy, vol 14, iss 1 (2022)
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Hippocampal ensembles represent sequential relationships among an extended sequence of nonspatial events.
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In: Nature communications, vol 13, iss 1 (2022)
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Neural dynamics of semantic categorization in semantic variant of primary progressive aphasia.
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| 6 |
Resting functional connectivity in the semantic appraisal network predicts accuracy of emotion identification.
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| 7 |
Development of thalamus mediates paternal age effect on offspring reading: A preliminary investigation.
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In: Human brain mapping, vol 42, iss 14 (2021)
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| 8 |
B Cell-Restricted Depletion of Dnmt3a Activates Notch Signaling and Causes Chronic Lymphocytic Leukemia
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In: Blood, vol 138, iss Supplement 1 (2021)
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Comparing two facets of emotion perception across multiple neurodegenerative diseases.
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In: Social cognitive and affective neuroscience, vol 15, iss 5 (2020)
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Abstract:
Deficits in emotion perception (the ability to infer others' emotions accurately) can occur as a result of neurodegeneration. It remains unclear how different neurodegenerative diseases affect different forms of emotion perception. The present study compares performance on a dynamic tracking task of emotion perception (where participants track the changing valence of a film character's emotions) with performance on an emotion category labeling task (where participants label specific emotions portrayed by film characters) across seven diagnostic groups (N = 178) including Alzheimer's disease (AD), behavioral variant frontotemporal dementia (bvFTD), semantic variant primary progressive aphasia (svPPA), non-fluent variant primary progressive aphasia (nfvPPA), progressive supranuclear palsy (PSP), corticobasal syndrome and healthy controls. Consistent with hypotheses, compared to controls, the bvFTD group was impaired on both tasks. The svPPA group was impaired on the emotion labeling task, whereas the nfvPPA, PSP and AD groups were impaired on the dynamic tracking task. Smaller volumes in bilateral frontal and left insular regions were associated with worse labeling, whereas smaller volumes in bilateral medial frontal, temporal and right insular regions were associated with worse tracking. Findings suggest labeling and tracking facets of emotion perception are differentially affected across neurodegenerative diseases due to their unique neuroanatomical correlates.
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Keyword:
2.1 Biological and endogenous factors; Acquired Cognitive Impairment; Aged; Aging; Alzheimer's Disease; Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD); Aphasia; Basic Behavioral and Social Science; Behavioral and Social Science; Brain Disorders; Cerebral Cortex; Clinical Research; cognitive empathy; Cognitive Sciences; dementia; emotion recognition; Emotions; empathic accuracy; Experimental Psychology; Female; Humans; lesion; Magnetic Resonance Imaging; Male; Middle Aged; Neurodegenerative; Neurodegenerative Diseases; Neurological; Neuropsychological Tests; Neurosciences; Perception; Psychology; Rare Diseases
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URL: https://escholarship.org/uc/item/4dn9m1gh
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| 10 |
Amount and delay insensitivity during intertemporal choice in three neurodegenerative diseases reflects dorsomedial prefrontal atrophy.
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| 11 |
Depressive Symptom Profiles Predict Specific Neurodegenerative Disease Syndromes in Early Stages.
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| 12 |
Depressive Symptom Profiles Predict Specific Neurodegenerative Disease Syndromes in Early Stages.
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| 13 |
Deformation-based shape analysis of the hippocampus in the semantic variant of primary progressive aphasia and Alzheimer's disease.
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| 14 |
Graded, multidimensional intra- and intergroup variations in primary progressive aphasia and post-stroke aphasia.
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In: Brain : a journal of neurology, vol 143, iss 10 (2020)
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| 15 |
Regional and hemispheric susceptibility of the temporal lobe to FTLD-TDP type C pathology.
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| 16 |
Amount and delay insensitivity during intertemporal choice in three neurodegenerative diseases reflects dorsomedial prefrontal atrophy.
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| 17 |
A neurophysiological model of speech production deficits in fragile X syndrome.
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In: Brain communications, vol 2, iss 1 (2020)
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The Relationship between Expressive Language Sampling and Clinical Measures in Fragile X Syndrome and Typical Development.
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In: Brain sciences, vol 10, iss 2 (2020)
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| 19 |
Contributions of common genetic variants to risk of schizophrenia among individuals of African and Latino ancestry.
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In: Molecular psychiatry, vol 25, iss 10 (2020)
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| 20 |
Contributions of common genetic variants to risk of schizophrenia among individuals of African and Latino ancestry.
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In: Molecular psychiatry, vol 25, iss 10 (2020)
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