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Speech- and Language-Based Classification of Alzheimer’s Disease: A Systematic Review
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In: Bioengineering; Volume 9; Issue 1; Pages: 27 (2022)
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A Meta-Analysis of Semantic Memory in Mild Cognitive Impairment
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In: ISSN: 1040-7308 ; EISSN: 1573-6660 ; Neuropsychology Review ; https://hal.archives-ouvertes.fr/hal-03015335 ; Neuropsychology Review, Springer Verlag, 2021, ⟨10.1007/s11065-020-09453-5⟩ (2021)
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Association Between Greater Cerebellar Network Connectivity and Improved Phonemic Fluency Performance After Exercise Training in Older Adults
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In: Psychology Faculty Research and Publications (2021)
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Un estudio tipológico de la metonimia en los chengyu derivados de Libro de los montes y los mares
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In: Tonos Digital; NÚMERO 42 - ENERO 2022 (2021)
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Semantic loss marks early Alzheimer's disease-related neurodegeneration in older adults without dementia
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VONK, J. M. J.; Bouteloup, Vincent; Mangin, J. F.; Dubois, B.; Blanc, F.; Gabelle, A.; Ceccaldi, Mathieu; Annweiler, Cédric; Krolak-Salmon, P.; Belin, C.; Rivasseau-Jonveaux, Thérèse; JULIAN, A.; Sellal, F.; Magnin, E.; Chupin, Marie; HABERT, M. O.; Chene, Genevieve; Dufouil, Carole
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In: ISSN: 2352-8729 ; Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring ; https://hal.archives-ouvertes.fr/hal-03148797 ; Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, Wiley, 2020, 12 (1), pp.1-14. ⟨10.1002/dad2.12066⟩ (2020)
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Abstract:
International audience ; Objective: To assess progression of semantic loss in early stages of cognitive decline using semantic and letter fluency performance, and its relation with Alzheimer's disease (AD)‐specific neurodegeneration using longitudinal multimodal neuroimaging measures.Methods: Change in verbal fluency was analyzed among 2261 non‐demented individuals with a follow‐up diagnosis of no mild cognitive impairment (MCI), amnestic MCI (aMCI), non‐amnestic MCI (naMCI), or incident dementia, using linear mixed models across 4 years of follow‐up, and relations with magnetic resonance imaging (MRI; n = 1536) and 18F‐fluorodeoxyglucose brain positron emission tomography (18F‐FDG‐PET) imaging (n = 756) using linear regression models across 2 years of follow‐up.Results: Semantic fluency declined—fastest in those at higher risk for AD (apolipoprotein E [APOE] e4 carriers, Clinical Dementia Rating score of .5, aMCI, or incident dementia)—while letter fluency did not except for those with incident dementia. Lower baseline semantic fluency was associated with an increase in white matter hyperintensities and total mean cortical thinning over time, and regionally with less hippocampal volume as well as more cortical thinning and reduced 18F‐FDG‐PET uptake in the inferior parietal lobule, entorhinal cortex, isthmus cingulate, and precuneus–posterior cingulate area. In contrast, baseline letter fluency was not associated with change in total nor regional neurodegeneration. Whole‐brain neurodegeneration over time was associated with faster decline in both fluencies, while AD‐specific regions were associated with a faster rate of decline in semantic but not letter fluency.Interpretation: This study provides strong evidence of distinctive degeneration of semantic abilities early on in relation to both cognitive decline and AD‐specific neurodegeneration.
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Keyword:
[SDV.NEU.SC]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Cognitive Sciences; Alzheimer’s disease; amnestic; biomarkers; category fluency; cognitive aging; cohort studies; letter fluency; MCI; neuroimaging; semantic fluency; verbal fluency
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URL: https://hal.archives-ouvertes.fr/hal-03148797 https://hal.archives-ouvertes.fr/hal-03148797/file/BPH_ADDADM_2020_Vonk.pdf https://hal.archives-ouvertes.fr/hal-03148797/document https://doi.org/10.1002/dad2.12066
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Development of Gaussian Learning Algorithms for Early Detection of Alzheimer's Disease
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In: FIU Electronic Theses and Dissertations (2020)
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EFECTOS DE PROTOTIPICIDAD DE NEÓNIMOS EN CONTEXTO
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In: Debate Terminológico. ISSN: 1813-1867; n. 18 (2020); 19-34 ; Debate Terminológico; n. 18 (2020); 19-34 ; 1813-1867 (2020)
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Exploitation vs. exploration—computational temporal and semantic analysis explains semantic verbal fluency impairment in Alzheimer's disease
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In: ISSN: 0028-3932 ; EISSN: 1873-3514 ; Neuropsychologia ; https://hal.archives-ouvertes.fr/hal-02339134 ; Neuropsychologia, Elsevier, 2019, 131, pp.53-61. ⟨10.1016/j.neuropsychologia.2019.05.007⟩ (2019)
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What is the lived experience of older migrants with mild cognitive impairment
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What is the lived experience of older migrants with mild cognitive impairment
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What is the lived experience of older migrants with mild cognitive impairment
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What is the lived experience of older migrants with mild cognitive impairment? A proposed phenomenological study
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What is the lived experience of older migrants with mild cognitive impairment? A proposed phenomenological study
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What is the lived experience of older migrants with mild cognitive impairment? A proposed phenomenological study
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Use of Speech Analyses within a mobile application for the Assessment of cognitive impairment in elderly people
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In: ISSN: 1567-2050 ; Current Alzheimer Research ; https://hal.inria.fr/hal-01672580 ; Current Alzheimer Research, Bentham Science Publishers, 2017, 14, pp.120 - 129. ⟨10.2174/1567205014666170829111942⟩ (2017)
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Contribution of language studies to the understanding of cognitive impairment and its progression over time in Parkinson’s disease
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In: URLS in this field will appear hyperlinked in eScholarship. (2017)
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Contribution of language studies to the understanding of cognitive impairment and its progression over time in Parkinson’s disease
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In: https://www.sciencedirect.com/science/article/pii/S0149763417301331?via%3Dihub (2017)
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Differential Performance across Discourse Types in MCI and Dementia
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In: http://rave.ohiolink.edu/etdc/view?acc_num=osu1343676787 (2012)
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Task Deactivation Reductions and Atrophy within Parietal Default Mode Regions Are Overlapping but Only Weakly Correlated in Mild Cognitive Impairment
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In: Neuroscience Faculty Publications (2011)
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Functional Response in Ventral Temporal Cortex Differentiates Mild Cognitive Impairment from Normal Aging
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In: Neuroscience Faculty Publications (2010)
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