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All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Page: 1 2 3 4 5...9 Hits 1 – 20 of 166 1 A new genus of land planarian (Platyhelminthes, Geoplanidae) for a new ‘blind’ species ... Negrete, Lisandro; Francavilla, Marina Lenguas; Damborenea, Cristina. - : Taylor & Francis, 2022 BASE Show details 2 A new genus of land planarian (Platyhelminthes, Geoplanidae) for a new ‘blind’ species ... Negrete, Lisandro; Francavilla, Marina Lenguas; Damborenea, Cristina. - : Taylor & Francis, 2022 BASE Show details 3 Polygenic scores for intelligence, educational attainment and schizophrenia are differentially associated with core autism features, IQ, and adaptive behaviour in autistic individuals Warrier, Varun; Leblond, Claire,; Cliquet, Freddy... In: https://hal-pasteur.archives-ouvertes.fr/pasteur-03261146 ; 2021 (2021) BASE Show details 4 Recent selection of candidate genes for mammal domestication in Europeans and language change in Europe: a hypothesis ... Benítez-Burraco, Antonio; Chekalin, Evgeny; Bruskin, Sergey. - : Taylor & Francis, 2021 BASE Show details 5 Recent selection of candidate genes for mammal domestication in Europeans and language change in Europe: a hypothesis ... Benítez-Burraco, Antonio; Chekalin, Evgeny; Bruskin, Sergey. - : Taylor & Francis, 2021 BASE Show details 6 Powered air-purifying respirators used during the SARS-CoV-2 pandemic significantly reduce speech perception ... Weiss, Roxanne; Guchlerner, Leon; Weissgerber, Tobias. - : figshare, 2021 BASE Show details 7 Additional file 1 of Powered air-purifying respirators used during the SARS-CoV-2 pandemic significantly reduce speech perception ... Weiss, Roxanne; Guchlerner, Leon; Weissgerber, Tobias. - : figshare, 2021 BASE Show details 8 Additional file 1 of Powered air-purifying respirators used during the SARS-CoV-2 pandemic significantly reduce speech perception ... Weiss, Roxanne; Guchlerner, Leon; Weissgerber, Tobias. - : figshare, 2021 BASE Show details 9 Powered air-purifying respirators used during the SARS-CoV-2 pandemic significantly reduce speech perception ... Weiss, Roxanne; Guchlerner, Leon; Weissgerber, Tobias. - : figshare, 2021 BASE Show details 10 Evidence for dual-route morphological processing across the lifespan: data from Russian noun plurals ... Savinova, Elena; Malyutina, Svetlana. - : Taylor & Francis, 2021 BASE Show details 11 Evidence for dual-route morphological processing across the lifespan: data from Russian noun plurals ... Savinova, Elena; Malyutina, Svetlana. - : Taylor & Francis, 2021 BASE Show details 12 Subcellular relocalization and nuclear redistribution of the RNA methyltransferases TRMT1 and TRMT1L upon neuronal activation ... Jonkhout, Nicky; Cruciani, Sonia; Vieira, Helaine Graziele Santos. - : Taylor & Francis, 2021 BASE Show details 13 Subcellular relocalization and nuclear redistribution of the RNA methyltransferases TRMT1 and TRMT1L upon neuronal activation ... Jonkhout, Nicky; Cruciani, Sonia; Vieira, Helaine Graziele Santos. - : Taylor & Francis, 2021 BASE Show details 14 Additional file 5 of The protein-protein interaction ontology: for better representing and capturing the biological context of protein interaction ... Li, Mansheng; He, Qiang; Yang, Chunyuan. - : figshare, 2021 BASE Show details 15 Additional file 5 of The protein-protein interaction ontology: for better representing and capturing the biological context of protein interaction ... Li, Mansheng; He, Qiang; Yang, Chunyuan. - : figshare, 2021 BASE Show details 16 Molecular Biomarkers Predictive of Sertraline Treatment Response in Young Children With Autism Spectrum Disorder. Alolaby, Reem Rafik; Jiraanont, Poonnada; Durbin-Johnson, Blythe. - : eScholarship, University of California, 2020 BASE Show details 17 Molecular Biomarkers Predictive of Sertraline Treatment Response in Young Children With Autism Spectrum Disorder. Alolaby, Reem Rafik; Jiraanont, Poonnada; Durbin-Johnson, Blythe; Jasoliya, Mittal; Tang, Hiu-Tung; Hagerman, Randi; Tassone, Flora. - : eScholarship, University of California, 2020 Abstract: Sertraline is one among several selective serotonin reuptake inhibitors (SSRIs) that exhibited improvement of language development in Autism Spectrum Disorder (ASD); however, the molecular mechanism has not been elucidated. A double blind, randomized, 6-month, placebo-controlled, clinical trial of low-dose sertraline in children ages (3-6 years) with ASD was conducted at the UC Davis MIND Institute. It aimed at evaluating the efficacy and benefit with respect to early expressive language development and global clinical improvement. This study aimed to identify molecular biomarkers that might be key players in the serotonin pathway and might be predictive of a clinical response to sertraline. Fifty eight subjects with the diagnosis of ASD were randomized to sertraline or placebo. Eight subjects from the sertraline arm and five from the placebo arm discontinued from the study. Furthermore, four subjects did not have a successful blood draw. Hence, genotypes for 41 subjects (20 on placebo and 21 on sertraline) were determined for several genes involved in the serotonin pathway including the serotonin transporter-linked polymorphic region (5-HTTLPR), the tryptophan hydroxylase 2 (TPH2), and the Brain-Derived Neurotrophic Factor (BDNF). In addition, plasma levels of BDNF, Matrix metallopeptidase 9 (MMP-9) and a selected panel of cytokines were determined at baseline and post-treatment. Intent-to-treat analysis revealed several primary significant correlations between molecular changes and the Mullen Scales of Early Learning (MSEL) and Clinical Global Impression Scale - Improvement (CGI-I) of treatment and control groups but they were not significant after adjustment for multiple testing. Thus, sertraline showed no benefit for treatment of young children with ASD in language development or changes in molecular markers in this study. These results indicate that sertraline may not be beneficial for the treatment of children with ASD; however, further investigation of larger groups as well as longer term follow-up studies are warranted. Keyword: Autism Spectrum Disorders; Clinical Sciences; Genetics; Law; molecular biomarkers; selective serotonin reuptake inhibitor; serotonin; sertraline URL: https://escholarship.org/uc/item/3n6774pz BASE Hide details 18 Cleaning up translation failures: how Ribosome-associated Quality Control maintains cellular proteostasis Hickey, Kelsey. - : eScholarship, University of California, 2020 BASE Show details 19 ОБРАТНАЯ ТРАНСЛЯЦИЯ С АНГЛИЙСКОГО ЯЗЫКА НА ДНК: КАК ЗАКОДИРОВАТЬ ПОСЛАНИЕ В ГЕНОМЕ ... АНДРЕЕВ П.Ю.; ИЛЬИНА И.С.. - : Международный журнал гуманитарных и естественных наук, 2020 BASE Show details 20 Additional file 1 of Usefulness of interferon-γ release assay for the diagnosis of sputum smear-negative pulmonary and extra-pulmonary TB in Zhejiang Province, China ... Ji, Lei; Lou, Yong-Liang; Zhong-Xiu Wu. - : figshare, 2020 BASE Show details Page: 1 2 3 4 5...9

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