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Functional Connectivity and Speech Entrainment Speech Entrainment Improves Connectivity Between Anterior and Posterior Cortical Speech Areas in Non-fluent Aphasia ...
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Functional Connectivity and Speech Entrainment Speech Entrainment Improves Connectivity Between Anterior and Posterior Cortical Speech Areas in Non-fluent Aphasia ...
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3
Speech Entrainment Improves Connectivity Between Anterior and Posterior Cortical Speech Areas in Non-Fluent Aphasia
In: Neurorehabil Neural Repair (2022)
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Neural correlates of impaired vocal feedback control in post-stroke aphasia
In: Neuroimage (2022)
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sj-docx-1-nnr-10.1177_1545968321999052 – Supplemental material for Indirect White Matter Pathways Are Associated With Treated Naming Improvement in Aphasia ...
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Indirect White Matter Pathways Are Associated With Treated Naming Improvement in Aphasia ...
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Indirect White Matter Pathways Are Associated With Treated Naming Improvement in Aphasia ...
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sj-docx-1-nnr-10.1177_1545968321999052 – Supplemental material for Indirect White Matter Pathways Are Associated With Treated Naming Improvement in Aphasia ...
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9
Cortical microstructural changes associated with treated aphasia recovery
In: Ann Clin Transl Neurol (2021)
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10
Isolating the white matter circuitry of the dorsal language stream: Connectome‐Symptom Mapping in stroke induced aphasia
In: Hum Brain Mapp (2021)
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11
Protocol for Escitalopram and Language Intervention for Subacute Aphasia (ELISA): A randomized, double blind, placebo-controlled trial
In: PLoS One (2021)
Abstract: In this forthcoming multicenter, prospective, randomized, double-blind placebo-controlled trial, we will investigate the augmentative effects of a selective serotonin reuptake inhibitor, escitalopram, on language therapy in individuals with post-stroke aphasia. We hypothesize that, when combined with language therapy, daily escitalopram will result in greater improvement than placebo in an untrained picture naming task (Philadelphia Naming Test short form) administered one week after the end of language therapy. We also will examine whether escitalopram’s effect on language is independent of its effect on depression, varies with lesion location, or is associated with increased functional connectivity within the left hemisphere. Finally, we will examine whether individuals with BDNF met alleles show reduced response to treatment and reduced changes in connectivity. We expect to enroll 88 participants over four years. Participants are given escitalopram or placebo within one week of their stroke for 90 days and receive fifteen 45-minute computer-delivered sessions of language treatment beginning 60 days from the start of drug therapy. Patients then complete a comprehensive assessment of language at one, five, and twenty weeks after the last language therapy session. ELISA is the first randomized, controlled trial evaluating the effect of a selective serotonin reuptake inhibitor on the improvement of language in people with aphasia undergoing language treatment during the acute to subacute post-stroke period. Trial registration: The trial is registered with ClinicalTrials.gov NCT03843463.
Keyword: Study Protocol
URL: https://doi.org/10.1371/journal.pone.0261474
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699636/
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12
Independent contributions of structural and functional connectivity: Evidence from a stroke model
In: Netw Neurosci (2021)
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13
Indirect white matter pathways are associated with treated naming improvement in aphasia
In: Neurorehabil Neural Repair (2021)
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14
2018 ASHA Research Symposium: Julius Fridricksson, BDNF Genotype & Brain Activation in Aphasia ...
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2018 ASHA Research Symposium: Julius Fridricksson, BDNF Genotype & Brain Activation in Aphasia ...
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16
Clinical Implementation of Transcranial Direct Current Stimulation in Aphasia: A Survey of Speech-Language Pathologists
In: Am J Speech Lang Pathol (2020)
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17
Machine learning‐based multimodal prediction of language outcomes in chronic aphasia
In: Hum Brain Mapp (2020)
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Progression of aphasia severity (Johnson et al., 2019) ...
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Progression of aphasia severity (Johnson et al., 2019) ...
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Progression of aphasia severity (Johnson et al., 2019) ...
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