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All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Page: 1 2 3 Hits 1 – 20 of 47 1 Lesion site and therapy time predict responses to a therapy for anomia after stroke: a prognostic model development study Akkad, H.; Nardo, D.; Crinion, J.; Leff, A.; Ondobaka, S.; Price, C. J.; Holland, R.; Hope, T.. - 2021 Abstract: Stroke is a leading cause of disability, and language impairments (aphasia) after stroke are both common and particularly feared. Most stroke survivors with aphasia exhibit anomia (difficulties with naming common objects), but while many therapeutic interventions for anomia have been proposed, treatment effects are typically much larger in some patients than others. Here, we asked whether that variation might be more systematic, and even predictable, than previously thought. 18 patients, each at least 6 months after left hemisphere stroke, engaged in a computerised treatment for their anomia over a 6-week period. Using only: (a) the patients' initial accuracy when naming (to-be) trained items; (b) the hours of therapy that they devoted to the therapy; and (c) whole-brain lesion location data, derived from structural MRI; we developed Partial Least Squares regression models to predict the patients' improvements on treated items, and tested them in cross-validation. Somewhat surprisingly, the best model included only lesion location data and the hours of therapy undertaken. In cross-validation, this model significantly out-performed the null model, in which the prediction for each patient was simply the mean treatment effect of the group. This model also made promisingly accurate predictions in absolute terms: the correlation between empirical and predicted treatment response was 0.62 (95% CI 0.27, 0.95). Our results indicate that individuals' variation in response to anomia treatment are, at least somewhat, systematic and predictable, from the interaction between where and how much lesion damage they have suffered, and the time they devoted to the therapy. Keyword: P Philology. Linguistics; RC Internal medicine URL: https://openaccess.city.ac.uk/id/eprint/26830/ https://doi.org/10.1038/s41598-021-97916-x https://openaccess.city.ac.uk/id/eprint/26830/1/Scientific_Reports_post_stroke.pdf BASE Hide details 2 Lesion-site-dependent responses to therapy after aphasic stroke Aguilar, OM; Kerry, SJ; Ong, Y-H. - 2018 BASE Show details 3 Auditory training changes temporal lobe connectivity in ‘Wernicke’s aphasia’: a randomised trial Woodhead, ZVJ; Crinion, J; Teki, S. - 2017 BASE Show details 4 Modulation of frontal effective connectivity during speech Holland, R.; Leff, A.; Penny, W. D.. - : Elsevier, 2016 BASE Show details 5 Comparing language outcomes in monolingual and bilingual stroke patients. Hope, TM; Parker Jones, '; Grogan, A... In: Brain , 138 (Pt 4) 1070 - 1083. (2015) (2015) BASE Show details 6 An area essential for linking word meanings to word forms: Evidence from primary progressive aphasia Race, D.S.; Tsapkini, K.; Crinion, J.... In: Brain & language. - Orlando, Fla. [u.a.] : Elsevier 127 (2013) 2, 167-176 OLC Linguistik Show details 7 An area essential for linking word meanings to word forms: evidence from primary progressive aphasia. Hillis, AE; Race, DS; Gomez, Y... In: Brain Lang , 127 (2) 167 - 176. (2013) (2013) BASE Show details 8 Priming Naming Holland, R; Leff, A; Price, C... In: In: 51ST ACADEMY OF APHASIA PROCEEDINGS. (pp. 74 - 75). (2013) (2013) BASE Show details 9 Neuroimaging in aphasia treatment research: Consensus and practical guidelines for data analysis (vol 73, pg 215, 2013) Meinzer, M; Beeson, PM; Cappa, S... In: NEUROIMAGE , 81 507 - 507. (2013) (2013) BASE Show details 10 Convergence, Degeneracy, and Control Green, DW; Crinion, J; Price, CJ In: In: (2013) (2013) BASE Show details 11 An Area Essential for Linking Word Meanings to Word Forms: Evidence from Primary Progressive Aphasia Race, D.S.; Tsapkini, K.; Crinion, J.. - 2013 BASE Show details 12 Can tDCS enhance treatment of aphasia after stroke? Holland, R.; Crinion, J.. - : Taylor & Francis, 2012 BASE Show details 13 Structural correlates for lexical efficiency and number of languages in non-native speakers of English Grogan, A.; Parker Jones, ‘Ō.; Ali, N.. - : Pergamon Press, 2012 BASE Show details 14 Speech Facilitation by Left Inferior Frontal Cortex Stimulation Holland, R.; Leff, A.; Josephs, O.. - : Elsevier, 2011 BASE Show details 15 Parallel recovery in a trilingual speaker: the use of the Bilingual Aphasia Test as a diagnostic complement to the Comprehensive Aphasia Test Green, D.W.; Ruffle, L.; Grogan, A.. - : Taylor & Francis, 2011 BASE Show details 16 Speech Facilitation by Left Inferior Frontal Cortex Stimulation Holland, R; Leff, AP; Josephs, O... In: CURR BIOL , 21 (16) 1403 - 1407. (2011) (2011) BASE Show details 17 Patterns of breakdown in spelling in primary progressive aphasia. Sepelyak, K; Crinion, J; Molitoris, J... In: Cortex , 47 (3) 342 - 352. (2011) (2011) BASE Show details 18 Parallel recovery in a trilingual speaker: the use of the Bilingual Aphasia Test as a diagnostic complement to the Comprehensive Aphasia Test Green, DW; Ruffle, L; Grogan, A... In: CLIN LINGUIST PHONET , 25 (6-7) 499 - 512. (2011) (2011) BASE Show details 19 Parallel recovery in a trilingual speaker: the use of the Bilingual Aphasia Test as a diagnostic complement to the Comprehensive Aphasia Test Green, DW; RUFFLE, L; Grogan, A... In: Clinical Linguistics and Phonetics 1 - 14. (2011) (2011) BASE Show details 20 Parallel recovery in a trilingual speaker: The use of the bilingual aphasia test as a diagnostic complement to the comprehensive aphasia test Green, DW; Ruffle, L; Grogan, A... In: Clinical Linguistics and Phonetics , 25 (6-7) 499 - 512. (2011) (2011) BASE Show details Page: 1 2 3

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