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All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Page: 1 2 3 Hits 1 – 20 of 47 1 Lesion site and therapy time predict responses to a therapy for anomia after stroke: a prognostic model development study Akkad, H.; Nardo, D.; Crinion, J.. - 2021 BASE Show details 2 Lesion-site-dependent responses to therapy after aphasic stroke Aguilar, OM; Kerry, SJ; Ong, Y-H. - 2018 BASE Show details 3 Auditory training changes temporal lobe connectivity in ‘Wernicke’s aphasia’: a randomised trial Woodhead, ZVJ; Crinion, J; Teki, S; Penny, W; Price, CJ; Leff, AP. - 2017 Abstract: Introduction Aphasia is one of the most disabling sequelae after stroke, occurring in 25%–40% of stroke survivors. However, there remains a lack of good evidence for the efficacy or mechanisms of speech comprehension rehabilitation. Trial Design This within-subjects trial tested two concurrent interventions in 20 patients with chronic aphasia with speech comprehension impairment following left hemisphere stroke: (1) phonological training using ‘Earobics’ software and (2) a pharmacological intervention using donepezil, an acetylcholinesterase inhibitor. Donepezil was tested in a double-blind, placebo-controlled, cross-over design using block randomisation with bias minimisation. Methods The primary outcome measure was speech comprehension score on the comprehensive aphasia test. Magnetoencephalography (MEG) with an established index of auditory perception, the mismatch negativity response, tested whether the therapies altered effective connectivity at the lower (primary) or higher (secondary) level of the auditory network. Results Phonological training improved speech comprehension abilities and was particularly effective for patients with severe deficits. No major adverse effects of donepezil were observed, but it had an unpredicted negative effect on speech comprehension. The MEG analysis demonstrated that phonological training increased synaptic gain in the left superior temporal gyrus (STG). Patients with more severe speech comprehension impairments also showed strengthening of bidirectional connections between the left and right STG. Conclusions Phonological training resulted in a small but significant improvement in speech comprehension, whereas donepezil had a negative effect. The connectivity results indicated that training reshaped higher order phonological representations in the left STG and (in more severe patients) induced stronger interhemispheric transfer of information between higher levels of auditory cortex. Keyword: magnetoencephalography; pharmacological trial; phonological training; speech comprehension; Wernicke’s aphasia URL: https://doi.org/10.1136/jnnp-2016-314621 BASE Hide details 4 Modulation of frontal effective connectivity during speech Holland, R.; Leff, A.; Penny, W. D.. - : Elsevier, 2016 BASE Show details 5 Comparing language outcomes in monolingual and bilingual stroke patients. Hope, TM; Parker Jones, '; Grogan, A... In: Brain , 138 (Pt 4) 1070 - 1083. (2015) (2015) BASE Show details 6 An area essential for linking word meanings to word forms: Evidence from primary progressive aphasia Race, D.S.; Tsapkini, K.; Crinion, J.... In: Brain & language. - Orlando, Fla. [u.a.] : Elsevier 127 (2013) 2, 167-176 OLC Linguistik Show details 7 An area essential for linking word meanings to word forms: evidence from primary progressive aphasia. Hillis, AE; Race, DS; Gomez, Y... In: Brain Lang , 127 (2) 167 - 176. (2013) (2013) BASE Show details 8 Priming Naming Holland, R; Leff, A; Price, C... In: In: 51ST ACADEMY OF APHASIA PROCEEDINGS. (pp. 74 - 75). (2013) (2013) BASE Show details 9 Neuroimaging in aphasia treatment research: Consensus and practical guidelines for data analysis (vol 73, pg 215, 2013) Meinzer, M; Beeson, PM; Cappa, S... In: NEUROIMAGE , 81 507 - 507. (2013) (2013) BASE Show details 10 Convergence, Degeneracy, and Control Green, DW; Crinion, J; Price, CJ In: In: (2013) (2013) BASE Show details 11 An Area Essential for Linking Word Meanings to Word Forms: Evidence from Primary Progressive Aphasia Race, D.S.; Tsapkini, K.; Crinion, J.. - 2013 BASE Show details 12 Can tDCS enhance treatment of aphasia after stroke? Holland, R.; Crinion, J.. - : Taylor & Francis, 2012 BASE Show details 13 Structural correlates for lexical efficiency and number of languages in non-native speakers of English Grogan, A.; Parker Jones, ‘Ō.; Ali, N.. - : Pergamon Press, 2012 BASE Show details 14 Speech Facilitation by Left Inferior Frontal Cortex Stimulation Holland, R.; Leff, A.; Josephs, O.. - : Elsevier, 2011 BASE Show details 15 Parallel recovery in a trilingual speaker: the use of the Bilingual Aphasia Test as a diagnostic complement to the Comprehensive Aphasia Test Green, D.W.; Ruffle, L.; Grogan, A.. - : Taylor & Francis, 2011 BASE Show details 16 Speech Facilitation by Left Inferior Frontal Cortex Stimulation Holland, R; Leff, AP; Josephs, O... In: CURR BIOL , 21 (16) 1403 - 1407. (2011) (2011) BASE Show details 17 Patterns of breakdown in spelling in primary progressive aphasia. Sepelyak, K; Crinion, J; Molitoris, J... In: Cortex , 47 (3) 342 - 352. (2011) (2011) BASE Show details 18 Parallel recovery in a trilingual speaker: the use of the Bilingual Aphasia Test as a diagnostic complement to the Comprehensive Aphasia Test Green, DW; Ruffle, L; Grogan, A... In: CLIN LINGUIST PHONET , 25 (6-7) 499 - 512. (2011) (2011) BASE Show details 19 Parallel recovery in a trilingual speaker: the use of the Bilingual Aphasia Test as a diagnostic complement to the Comprehensive Aphasia Test Green, DW; RUFFLE, L; Grogan, A... In: Clinical Linguistics and Phonetics 1 - 14. (2011) (2011) BASE Show details 20 Parallel recovery in a trilingual speaker: The use of the bilingual aphasia test as a diagnostic complement to the comprehensive aphasia test Green, DW; Ruffle, L; Grogan, A... In: Clinical Linguistics and Phonetics , 25 (6-7) 499 - 512. (2011) (2011) BASE Show details Page: 1 2 3

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