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All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Hits 1 – 9 of 9 1 tRNA(Ini) (CAT) inhibits proliferation and promotes apoptosis of laryngeal squamous cell carcinoma cells Li, Jun; Shen, Zhisen; Luo, Lin; Ye, Dong; Deng, Hongxia; Gu, Shanshan; Zhou, Chongchang In: J Clin Lab Anal (2021) Abstract: BACKGROUND: Laryngeal squamous cell carcinoma (LSCC) brings a heavy blow to the patient's voice. Transfer RNA (tRNA) is a common RNA, the roles of tRNAs in LSCC are largely unknown. METHODS: The tRNA expression profile in LSCC tissues and adjacent normal tissues was measured by a tRNA qRT‐PCR array. The expression level of tRNA(Ini) (CAT) in LSCC tissues and plasmas was detected by qRT‐PCR. The receiver operating characteristic (ROC) curve was established. tRNA(Ini) (CAT) was upregulated by a lentivirus vector in the LSCC cell line. Moreover, tRNA(Ini) (CAT) was upregulated in LSCC xenograft nude mouse model and the xenografts were used for pathological analysis and transmission electron microscope (TEM) observation. RESULTS: The top 10 upregulated tRNAs were tRNA(Lys) (CTT)‐1, tRNA(Leu) (TAA), tRNA(Phe) (GAA), tRNA(Leu) (CAG), tRNA(Tyr) (ATA), tRNA(Met) (CAT), tRNA(Tyr) (GTA)‐1, tRNA(Thr) (CGT), tRNA(Tyr) (GTA)‐2, tRNA(Ala) (AGC); and the top 10 downregulated tRNAs were tRNA(Ini) (CAT), mt‐tRNA(Glu) (TTC), tRNA(Val) (CAC)‐3, mt‐tRNA(Trp) (TCA), mt‐tRNA(Tyr) (GTA), mt‐tRNA(Lys) (TTT), mt‐tRNA(Thr) (TGT), mt‐tRNA(Asp) (GTC), mt‐tRNA(Asn) (GTT), mt‐tRNA(Pro) (TGG). tRNA(Ini) (CAT) was downregulated in LSCC tissues and plasma. The area under the ROC curve (AUC) in LSCC tissues and the plasma of patients with LSCC was 0.717 and 0.808, respectively. tRNA(Ini) (CAT) inhibited LSCC cell proliferation and promoted apoptosis. The in vivo results showed that tRNA(Ini) (CAT) inhibited the growth of the xenografts and promoted apoptosis. CONCLUSIONS: This is the first study to provide tRNA expression profiles for LSCC tissues. tRNA(Ini) (CAT) may be used as a new biomarker for the early diagnosis of LSCC. tRNA(Ini) (CAT) inhibits cell proliferation and promotes apoptosis in vitro and in vivo. Keyword: Research Articles URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8274982/ http://www.ncbi.nlm.nih.gov/pubmed/34048096 https://doi.org/10.1002/jcla.23821 BASE Hide details 2 Effects of Bilingualism and Aging on Executive Function and Working Memory Bialystok, Ellen; Poarch, Gregory; Luo, Lin. - 2014 BASE Show details 3 Proficiency and Control in Verbal Fluency Performance across the Lifespan for Monolinguals and Bilinguals Friesen, Deanna C.; Luo, Lin; Luk, Gigi. - 2014 BASE Show details 4 Proficiency and control in verbal fluency performance across the lifespan for monolinguals and bilinguals Friesen, Deanna C.; Luo, Lin; Luk, Gigi. - : Informa UK Limited, 2013 BASE Show details 5 Effect of language proficiency and executive control on verbal fluency performance in bilinguals Luo, Lin; Luk, Gigi; Bialystok, Ellen In: Cognition. - Amsterdam [u.a] : Elsevier 114 (2010) 1, 29-41 OLC Linguistik Show details 6 Does bilingualism help memory? Competing effects of verbal ability and executive control Wodniecka, Zofia; Luo, Lin; Bialystok, Ellen... In: International journal of bilingual education and bilingualism. - Abingdon : Routledge, Taylor & Francis Group 13 (2010) 5, 575-595 BLLDB OLC Linguistik Show details 7 Effect of language proficiency and executive control on verbal fluency performance in bilinguals Luo, Lin; Luk, Gigi; Bialystok, Ellen In: Cognition. - Amsterdam [u.a] : Elsevier 114 (2010) 1, 29-41 BLLDB Show details 8 Effect of language proficiency and executive control on verbal fluency performance in bilinguals Luo, Lin; Luk, Gigi; Bialystok, Ellen. - : Elsevier BV, 2010 BASE Show details 9 Age differences in recollection: specificity effects at retrieval Craik, Fergus I. M.; Luo, Lin In: Journal of memory and language. - Amsterdam [u.a.] : Elsevier 60 (2009) 4, 421-436 BLLDB OLC Linguistik Show details

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