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1
Processing of Degraded Speech in Brain Disorders
Jiang, J; Benhamou, E; Waters, S. - : MDPI AG, 2021
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2
Findings of Impaired Hearing in Patients With Nonfluent/Agrammatic Variant Primary Progressive Aphasia.
Hardy, CJD; Frost, C; Sivasathiaseelan, H. - : American Medical Association, 2019
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3
Hearing and dementia
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4
Impaired Interoceptive Accuracy in Semantic Variant Primary Progressive Aphasia
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5
Behavioural and neuroanatomical correlates of auditory speech analysis in primary progressive aphasias
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6
Primary progressive aphasia: a clinical approach
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7
Teaching NeuroImages: Nonfluent variant primary progressive aphasia A distinctive clinico-anatomical syndrome
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8
The TMEM106B risk allele is associated with lower cortical volumes in a clinically diagnosed frontotemporal dementia cohort.
In: J Neurol Neurosurg Psychiatry (2017) (2017)
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9
Processing emotion from abstract art in frontotemporal lobar degeneration
In: Neuropsychologia , 81 pp. 245-254. (2016) (2016)
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10
Hearing and dementia.
In: Journal of Neurology (2016) (2016)
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11
Binary reversals in primary progressive aphasia
In: Cortex , 82 pp. 287-289. (2016) (2016)
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12
Dementias show differential physiological responses to salient sounds.
In: Front Behav Neurosci , 9 , Article 73. (2015) (2015)
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13
Pain and temperature processing in dementia: a clinical and neuroanatomical analysis
In: Brain , 138 (11) pp. 3360-3372. (2015) (2015)
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14
The Language Profile of Behavioral Variant Frontotemporal Dementia
In: Journal of Alzheimer's Disease , 50 (2) pp. 359-371. (2015) (2015)
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15
Delayed auditory feedback simulates features of nonfluent primary progressive aphasia.
In: J Neurol Sci , 347 (1-2) 345 - 348. (2014) (2014)
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16
Delayed auditory feedback simulates features of nonfluent primary progressive aphasia
In: Journal of the Neurological Sciences , 347 (1-2) 345 - 348. (2014) (2014)
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17
'THE MIND IS ITS OWN PLACE': AMELIORATION OF CLAUSTROPHOBIA IN A PATIENT WITH SEMANTIC DEMENTIA
Clarke, Camilla; Fletcher, P; Cifelli, A; Warren, JD. - : BMJ Publishing Group Ltd, 2013
Abstract: Specific phobia is defined as marked, persistent and excessive or unreasonable fear when in the presence of, or when anticipating an encounter with, a specific object or situation.1 Here we describe amelioration of one common and disabling example, claustrophobia, following the onset of semantic dementia. Our patient had a clinical diagnosis of claustrophobia dating from her 20s and severe enough to cause her difficulties in daily life. She had habitually avoided lifts, windowless rooms, train travel and flying on account of her intense fear of being enclosed. At the age of 61, she developed a typical syndrome of semantic dementia led by progressive loss of facial recognition, anomic aphasia with loss of verbal and nonverbal knowledge and characteristic asymmetric (predominantly right sided) anterior temporal lobe atrophy on brain MRI. Around 7 years after onset of first symptoms her family reported that her previously severe claustrophobia had essentially disappeared: she would now enter small rooms without evident distress and happily participated in a longitudinal research study involving regular MRI scans. Specific phobias are thought to be mediated neuroanatomically via limbic and paralimbic circuitry, including the amygdala, anterior cingulate and insula.2 These regions are all targeted in semantic dementia, while altered fronto–limbic connectivity has been described in frontotemporal lobar degeneration.3 Our patient's newfound fearlessness may reflect an interaction of damaged limbic and autonomic responsivity with loss of the cognitive meaning of previously threatening situations. More broadly, her case illustrates how the brain constructs a private model of the world and invests this with emotional significance, and how this process can be modulated by pathological mental states: as recognised long ago by John Milton, and others.
Keyword: 23-24 October 2013; Association of British Neurologists (ABN) joint meeting with the Royal College of Physicians (RCP); London
URL: https://doi.org/10.1136/jnnp-2013-306573.82
http://jnnp.bmj.com/cgi/content/short/84/11/e2-gt
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18
Intact reading in patients with profound early visual dysfunction.
In: Cortex , 49 (9) 2294 - 2306. (2013) (2013)
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19
Flavour identification in frontotemporal lobar degeneration.
In: J Neurol Neurosurg Psychiatry , 84 (1) 88 - 93. (2013) (2013)
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20
Patterns of longitudinal brain atrophy in the logopenic variant of primary progressive aphasia
In: Brain and Language , 127 (2) 121 - 126. (2013) (2013)
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