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Cross-Lingual Text-to-Speech Using Multi-Task Learning and Speaker Classifier Joint Training ...
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Global genetic differentiation of complex traits shaped by natural selection in humans.
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In: Nature communications, vol. 9, no. 1, pp. 1865 (2018)
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Using Network-Text Analysis to Characterise Learner Engagement in Active Video Watching
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EEG oscillations during word processing predict MCI conversion to Alzheimer's disease
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A hidden knowledge discovering approach for past tense and plural problems to language cognition
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Childhood intelligence is heritable, highly polygenic and associated with FNBP1L
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Childhood intelligence is heritable, highly polygenic and associated with FNBP1L
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Childhood intelligence is heritable, highly polygenic and associated with FNBP1L.
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In: Mol Psychiatry , 19 (2) 253 - 258. (2014) (2014)
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Childhood intelligence is heritable, highly polygenic and associated with FNBP1L
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Childhood intelligence is heritable, highly polygenic and associated with FNBP1L
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Childhood intelligence is heritable, highly polygenic and associated with FNBP1L
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DNA evidence for strong genome-wide pleiotropy of cognitive and learning abilities.
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In: Behav Genet , 43 (4) 267 - 273. (2013) (2013)
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Abstract:
Very different neurocognitive processes appear to be involved in cognitive abilities such as verbal and non-verbal ability as compared to learning abilities taught in schools such as reading and mathematics. However, twin studies that compare similarity for monozygotic and dizygotic twins suggest that the same genes are largely responsible for genetic influence on these diverse aspects of cognitive function. It is now possible to test this evidence for strong pleiotropy using DNA alone from samples of unrelated individuals. Here we used this new method with 1.7 million DNA markers for a sample of 2,500 unrelated children at age 12 to investigate for the first time the extent of pleiotropy between general cognitive ability (aka intelligence) and learning abilities (reading, mathematics and language skills). We also compared these DNA results to results from twin analyses using the same sample and measures. The DNA-based method revealed strong genome-wide pleiotropy: Genetic correlations were greater than 0.70 between general cognitive ability and language, reading, and mathematics, results that were highly similar to twin study estimates of genetic correlations. These results indicate that genes related to diverse neurocognitive processes have general rather than specific effects.
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Keyword:
Child; Cognition; DNA; England; Female; Genetic Markers; Genetic Pleiotropy; Genome; Genome-Wide Association Study; Human; Humans; Intelligence; Intelligence Tests; Language; Learning; Longitudinal Studies; Male; Multivariate Analysis; Neuropsychological Tests; Wales
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URL: http://discovery.ucl.ac.uk/1392978/
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Cardiorenal end points in a trial of aliskiren for type 2 diabetes.
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In: New England Journal of Medicine, vol. 367, no. 23, pp. 2204-2213 (2012)
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Children's perceptions of the impact of participation in an intercultural educational programme
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