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Cortical microstructure in primary progressive aphasia: a multicenter study.
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In: Alzheimer's research & therapy, vol 14, iss 1 (2022)
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A Preliminary Report of Network Electroencephalographic Measures in Primary Progressive Apraxia of Speech and Aphasia
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In: Brain Sciences; Volume 12; Issue 3; Pages: 378 (2022)
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Primary and Secondary Progressive Aphasia in Posterior Cortical Atrophy
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In: Life; Volume 12; Issue 5; Pages: 662 (2022)
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A 'Mini Linguistic State Examination' to classify primary progressive aphasia. ...
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A 'Mini Linguistic State Examination' to classify primary progressive aphasia. ...
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| 6 |
Improving the diagnostic accuracy of primary progressive aphasia using cognitive tests
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Foxe, David Gordon. - : The University of Sydney, 2022. : Faculty of Science, School of Psychology, 2022
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| 7 |
Neural substrates of verbal repetition deficits in primary progressive aphasia.
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| 8 |
Resting functional connectivity in the semantic appraisal network predicts accuracy of emotion identification.
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Neural dynamics of semantic categorization in semantic variant of primary progressive aphasia.
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| 10 |
Uniform data set language measures for bvFTD and PPA diagnosis and monitoring.
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In: Alzheimer's & dementia (Amsterdam, Netherlands), vol 13, iss 1 (2021)
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| 11 |
Resting functional connectivity in the semantic appraisal network predicts accuracy of emotion identification.
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| 12 |
What Do We Mean by Behavioral Disinhibition in Frontotemporal Dementia?
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| 13 |
Uniform data set language measures for bvFTD and PPA diagnosis and monitoring.
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Staffaroni, Adam M; Weintraub, Sandra; Rascovsky, Katya; Rankin, Katherine P; Taylor, Jack; Fields, Julie A; Casaletto, Kaitlin B; Hillis, Argye E; Lukic, Sladjana; Gorno-Tempini, Maria Luisa; Heuer, Hilary; Teylan, Merilee A; Kukull, Walter A; Miller, Bruce L; Boeve, Bradley F; Rosen, Howard J; Boxer, Adam L; Kramer, Joel H
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In: Alzheimer's & dementia (Amsterdam, Netherlands), vol 13, iss 1 (2021)
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Abstract:
IntroductionThe Frontotemporal Lobar Degeneration Module (FTLD-MOD) includes a neuropsychological battery designed to assess the clinical features of FTLD, although much is unknown about its utility. We investigated FTLD-MOD and Uniform Data Set 3.0 (UDS) language tests for differential diagnosis and disease monitoring.MethodsLinear regressions compared baseline performances in 1655 National Alzheimer's Coordinating Center participants (behavioral variant frontotemporal dementia (bvFTD, n=612), semantic variant primary progressive aphasia (svPPA, n=168), non-fluent/agrammatic variant PPA (nfvPPA, n=168), logopenic variant PPA (lvPPA, n=109), and controls (n=581)). Sample sizes to detect treatment effects were estimated using longitudinal data.ResultsAmong PPAs, the FTLD-MOD language tasks and UDS Multilingual Naming Test accurately discriminated svPPA. Number Span Forward best discriminated lvPPA; Phonemic:Semantic Fluency ratio was excellent for nfvPPA classification. UDS fluency and naming measures required the smallest sample size to detect meaningful change.DiscussionThe FTLD-MOD and UDS differentiated among PPA subtypes. UDS 3.0 measures performed best for longitudinal monitoring.
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Keyword:
Acquired Cognitive Impairment; Aging; Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD); Alzheimer's Disease Related Dementias (ADRD); Aphasia; Brain Disorders; Clinical Research; clinical trials; Clinical Trials and Supportive Activities; cognition; Dementia; differential diagnosis; endpoints; frontotemporal dementia; Frontotemporal Dementia (FTD); FTLD module; Genetics; longitudinal; Neurodegenerative; neuropsychology; Neurosciences; primary progressive aphasia; Rare Diseases; speech
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URL: https://escholarship.org/uc/item/31v6d3qh
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| 14 |
What Do We Mean by Behavioral Disinhibition in Frontotemporal Dementia?
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| 15 |
Primary Progressive Aphasia: Use of Graphical Markers for an Early and Differential Diagnosis
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In: Brain Sciences ; Volume 11 ; Issue 9 (2021)
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Survival in the Three Common Variants of Primary Progressive Aphasia: A Retrospective Study in a Tertiary Memory Clinic
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In: Brain Sciences ; Volume 11 ; Issue 9 (2021)
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| 17 |
Application of Machine Learning to Electroencephalography for the Diagnosis of Primary Progressive Aphasia: A Pilot Study
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In: Brain Sciences ; Volume 11 ; Issue 10 (2021)
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| 18 |
Longitudinal Changes in Cognition, Behaviours, and Functional Abilities in the Three Main Variants of Primary Progressive Aphasia: A Literature Review
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In: Brain Sciences ; Volume 11 ; Issue 9 (2021)
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Verbal Short-Term Memory Disturbance in the Primary Progressive Aphasias: Challenges and Distinctions in a Clinical Setting
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In: Brain Sciences ; Volume 11 ; Issue 8 (2021)
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| 20 |
Treatment for Anomia in Bilingual Speakers with Progressive Aphasia
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In: Brain Sciences ; Volume 11 ; Issue 11 (2021)
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