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Differentiating profiles of speech impairments in Friedreich's ataxia: a perceptual and instrumental approach
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Measures of spectral change and their application to habitual, slow, and clear speaking modes
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Spectral measures of the effects of Friedreich's ataxia on speech
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Kinematic analysis of lingual movements during consonant productions in dysarthric speakers with Friedreich's ataxia: A case-by-case analysis
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Modulation of N400 in chronic non-fluent aphasia using low frequency Repetitive Transcranial Magnetic Stimulation (rTMS)
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Abstract:
Low frequency Repetitive Transcranial Magnetic Stimulation (rTMS) has previously been applied to language homologues in non-fluent populations of persons with aphasia yielding significant improvements in behavioral language function up to 43. months post stimulation. The present study aimed to investigate the electrophysiological correlates associated with the application of rTMS through measurement of the semantic based N400 Event-related brain potentials (ERP) component. Low frequency (1. Hz) rTMS was applied to the anterior portion of the homologue to Broca's area (pars triangularis), for 20. min per day for 10. days, using a stereotactic neuronavigational system. Twelve non-fluent persons with aphasia, 2-6. years post stroke were stimulated. Six participants were randomly assigned to receive real stimulation and six participants were randomly assigned to receive a blind sham control condition. ERP measures were recorded at baseline, 1. week and 2. months subsequent to stimulation. The findings demonstrate treatment related changes observed in the stimulation group when compared to the placebo control group at 2. months post stimulation indicating neuromodulation of N400 as a result of rTMS. No treatment related changes were identified in the stimulation group, when compared to the sham group from baseline to 1. week post stimulation. The electrophysiological results represent the capacity of rTMS to modulate neural language networks and measures of lexical-semantic function in participants with non-fluent aphasia and suggest that time may be an important factor in brain reorganization subsequent to rTMS. © 2010 Elsevier Inc.
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Keyword:
2805 Cognitive Neuroscience; 3205 Experimental and Cognitive Psychology; 3310 Linguistics and Language; 3616 Speech and Hearing; Audiology & Speech-Language Pathology; Experimental; Linguistics; Neurosciences; Neurosciences & Neurology; Psychology
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URL: https://espace.library.uq.edu.au/view/UQ:231025
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Differentiating Impairment Levels in Temporal Versus Spatial Aspects of Linguopalatal Contacts in Friedreich's Ataxia
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Articulatory disturbance in Friedreich's ataxia: An electropalatographic study
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In: 13th International Congress of Parkinsons Disease and Movement Disorders (2009)
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Speech production in Parkinson's disease: II. Acoustic and electropalatographic investigation of sentence, word and segment durations
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Speech production in Parkinson's disease: I. An electropalatographic investigation of tongue-palate contact patterns
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Six-month outcome for dysphagia following traumatic brain injury: Radiological assessment.
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In: Journal of Medical Speech - Language Pathology , 13 (2) pp. 109-125. (2005) (2005)
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Analysis of articulatory dynamics in dysarthria following brain injury in childhood using electromagnetic articulography and electropalatography
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Kinematic analysis of jaw function in children following traumatic brain injury
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Articulatory function following traumatic brain injury in childhood: A perceptual and instrumental analysis
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The mismatch negativity (MMN) response to complex tones and spoken words in individuals with aphasia
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Perceptual and instrumental evaluation of voice and tongue function after carotid endarterectomy
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The relationship between the mismatch negativity (MMN) and psycholinguistic models of spoken word processing
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Perceptual and instrumental analysis of laryngeal function after traumatic brain injury in childhood
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Complex language functions and subcortical mechanisms: evidence from Huntington's disease and patients with non-thalamic subcortical lesions
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Use of electromagnetic articulography in the assessment of articulatory dysfunction in patients with speech disorders subsequent to traumatic brain injury
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