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1
Neural substrates of verbal repetition deficits in primary progressive aphasia.
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2
Breakdowns in Informativeness of Naturalistic Speech Production in Primary Progressive Aphasia
In: MDPI (2021)
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3
Breakdowns in Informativeness of Naturalistic Speech Production in Primary Progressive Aphasia
In: Multidisciplinary Digital Publishing Institute (2021)
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4
A category-selective semantic memory deficit for animate objects in semantic variant primary progressive aphasia
In: Brain Commun (2021)
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5
Neural substrates of verbal repetition deficits in primary progressive aphasia
In: Brain Commun (2021)
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6
Differential Diagnosis of Apraxia of Speech in Children and Adults: A Scoping Review
In: Speech Pathology and Audiology Faculty Research and Publications (2020)
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7
Differential Diagnosis of Apraxia of Speech in Children and Adults: A Scoping Review
In: J Speech Lang Hear Res (2020)
Abstract: PURPOSE: Despite having distinct etiologies, acquired apraxia of speech (AOS) and childhood apraxia of speech (CAS) share the same central diagnostic challenge (i.e., isolating markers specific to an impairment in speech motor planning/programming). The purpose of this review was to evaluate and compare the state of the evidence on approaches to differential diagnosis for AOS and CAS and to identify gaps in each literature that could provide directions for future research aimed to improve clinical diagnosis of these disorders. METHOD: We conducted a scoping review of literature published between 1997 and 2019, following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews guidelines. For both AOS and CAS, literature was charted and summarized around four main methodological approaches to diagnosis: speech symptoms, quantitative speech measures, impaired linguistic–motor processes, and neuroimaging. RESULTS: Results showed that similar methodological approaches have been used to study differential diagnosis of apraxia of speech in adults and children; however, the specific measures that have received the most research attention differ between AOS and CAS. Several promising candidate markers for AOS and CAS have been identified; however, few studies report metrics that can be used to assess their diagnostic accuracy. CONCLUSIONS: Over the past two decades, there has been a proliferation of research identifying potential diagnostic markers of AOS and CAS. In order to improve clinical diagnosis of AOS and CAS, there is a need for studies testing the diagnostic accuracy of multiple candidate markers, better control over language impairment comorbidity, more inclusion of speech-disordered control groups, and an increased focus on translational work moving toward clinical implementation of promising measures.
Keyword: Speech
URL: http://www.ncbi.nlm.nih.gov/pubmed/32783767
https://doi.org/10.1044/2020_JSLHR-20-00061
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7890226/
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8
Quantitative assessment of motor speech impairment in primary progressive aphasia
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9
Table e-3. Operational guidelines for motor speech severity ratings ...
Cordella, Claire; Quimby, Megan; Touroutoglou, Alexandra. - : Dryad Digital Repository, 2019
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10
Table e-4. Motor speech features and criteria for diagnosing AOS, Dysarthria ...
Cordella, Claire; Quimby, Megan; Touroutoglou, Alexandra. - : Dryad Digital Repository, 2019
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11
Figure e-1. Motor speech regions of interest labelled using SpeechLabel parcellation paradigm ...
Cordella, Claire; Quimby, Megan; Touroutoglou, Alexandra. - : Dryad Digital Repository, 2019
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12
Data from: Quantification of motor speech impairment and its anatomic basis in primary progressive aphasia ...
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13
Table e-1. Baseline speech/language characteristics per patient ...
Cordella, Claire; Quimby, Megan; Touroutoglou, Alexandra. - : Dryad Digital Repository, 2019
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14
Table e-2. Supplemental CDR language domain as defined by Knopman, Weintraub, and Pankratz (2011) ...
Cordella, Claire; Quimby, Megan; Touroutoglou, Alexandra. - : Dryad Digital Repository, 2019
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15
Table e-5. Motor speech characterizations (consensus ratings) per patient ...
Cordella, Claire; Quimby, Megan; Touroutoglou, Alexandra. - : Dryad Digital Repository, 2019
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16
Quantification of motor speech impairment and its anatomic basis in primary progressive aphasia
Cordella, Claire; Quimby, Megan; Touroutoglou, Alexandra. - : Lippincott Williams & Wilkins, 2019
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17
Slowed articulation rate is a sensitive diagnostic marker for identifying non-fluent primary progressive aphasia
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