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Cross-Lingual Text-to-Speech Using Multi-Task Learning and Speaker Classifier Joint Training ...
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Global genetic differentiation of complex traits shaped by natural selection in humans.
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In: Nature communications, vol. 9, no. 1, pp. 1865 (2018)
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Using Network-Text Analysis to Characterise Learner Engagement in Active Video Watching
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EEG oscillations during word processing predict MCI conversion to Alzheimer's disease
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Abstract:
Only a subset of mild cognitive impairment (MCI) patients progress to develop a form of dementia. A prominent feature of Alzheimer's disease (AD) is a progressive decline in language. We investigated if subtle anomalies in EEG activity of MCI patients during a word comprehension task could provide insight into the likelihood of conversion to AD. We studied 25 amnestic MCI patients, a subset of whom developed AD within 3-years, and 11 elderly controls. In the task, auditory category descriptions (e.g., ‘a type of wood’) were followed by a single visual target word either semantically congruent (i.e., oak) or incongruent with the preceding category. We found that the MCI convertors group (i.e. patients that would go on to convert to AD in 3-years) had a diminished early posterior-parietal theta (3–5 Hz) activity induced by first presentation of the target word (i.e., access to lexico-syntactic properties of the word), compared to MCI non-convertors and controls. Moreover, MCI convertors exhibited oscillatory signatures for processing the semantically congruent words that were different from non-convertors and controls. MCI convertors thus showed basic anomalies for lexical and meaning processing. In addition, both MCI groups showed anomalous oscillatory signatures for the verbal learning/memory of repeated words: later alpha suppression (9–11 Hz), which followed first presentation of the target word, was attenuated for the second and third repetition in controls, but not in either MCI group. Our findings suggest that a subtle breakdown in the brain network subserving language comprehension can be foretelling of conversion to AD.
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Keyword:
QP Physiology (Living systems); R Medicine (General)
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URL: https://kar.kent.ac.uk/64541/1/Mazaheri_Neuroimage_Clinical.pdf https://kar.kent.ac.uk/64541/ https://doi.org/10.1016/j.nicl.2017.10.009
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A hidden knowledge discovering approach for past tense and plural problems to language cognition
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Childhood intelligence is heritable, highly polygenic and associated with FNBP1L
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Childhood intelligence is heritable, highly polygenic and associated with FNBP1L
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Childhood intelligence is heritable, highly polygenic and associated with FNBP1L.
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In: Mol Psychiatry , 19 (2) 253 - 258. (2014) (2014)
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Childhood intelligence is heritable, highly polygenic and associated with FNBP1L
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Childhood intelligence is heritable, highly polygenic and associated with FNBP1L
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Childhood intelligence is heritable, highly polygenic and associated with FNBP1L
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DNA evidence for strong genome-wide pleiotropy of cognitive and learning abilities.
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In: Behav Genet , 43 (4) 267 - 273. (2013) (2013)
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Cardiorenal end points in a trial of aliskiren for type 2 diabetes.
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In: New England Journal of Medicine, vol. 367, no. 23, pp. 2204-2213 (2012)
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Children's perceptions of the impact of participation in an intercultural educational programme
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