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Family history of FXTAS is associated with age-related cognitive-linguistic decline among mothers with the FMR1 premutation.
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In: Journal of neurodevelopmental disorders, vol 14, iss 1 (2022)
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Spectatoriale Geschlechterkonstruktionen: Geschlechtsspezifische Wissens- und Welterzeugung in den französisch- und spanischsprachigen Moralischen Wochenschriften des 18. Jahrhunderts
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Völkl, Yvonne. - : transcript Verlag, 2022. : DEU, 2022. : Bielefeld, 2022
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In: Gender Studies ; 355 (2022)
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Impact of factors specific to forced migration on German language acquisition: Family constellation, health status and housing situation
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In: 4-2020 ; BAMF-Brief Analysis ; 13 (2022)
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Neural dynamics of semantic categorization in semantic variant of primary progressive aphasia.
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Resting functional connectivity in the semantic appraisal network predicts accuracy of emotion identification.
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Adolescent Protective and Risk Factors for Incarceration through Early Adulthood
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In: JOURNAL OF CHILD AND FAMILY STUDIES, vol 30, iss 6 (2021)
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Development of thalamus mediates paternal age effect on offspring reading: A preliminary investigation.
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In: Human brain mapping, vol 42, iss 14 (2021)
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The effect of distance and frequency factors on the prominence of referential entities ; L’effet des facteurs de distance et de fréquence sur la saillance des entités référentielles
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In: ISSN: 0458-726X ; EISSN: 1958-9549 ; Langages ; https://hal.archives-ouvertes.fr/hal-03474751 ; Langages, Armand Colin (Larousse jusqu'en 2003), 2021, Un corpus annoté en chaînes de référence et son exploitation : le projet Democrat, pp.109-128 ; https://www.revues.armand-colin.com/lettres-langues/langages/langages-no-224-42021/ (2021)
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Evidence of the interplay of genetics and culture in Ethiopia. ...
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Web indirect language assessment on monolingual Italian toddlers ...
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Infant and Toddler Child-Care Quality and Stability in Relation to Proximal and Distal Academic and Social Outcomes.
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Sexualität - Geschlecht - Affekt: Sexuelle Scripts als Palimpsest in literarischen Erzähltexten und zeitgenössischen theoretischen Debatten
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In: Gender Studies ; 326 (2021)
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Do women and men use language differently in spoken face-to-face interaction? A scoping review
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In: Review of Communication Research ; 9 ; 43-79 (2021)
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The emotional impact of mixed proficiency levels in the corporate language in multinational teams
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Evidence of the interplay of genetics and culture in Ethiopia.
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In: essn: 2041-1723 ; nlmid: 101528555 (2021)
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Problems in Foreign Language Education in the Turkish Education System: Pre-Service Teachers’ Accounts
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In: Eurasian Journal of Applied Linguistics, Vol 7, Iss 1, Pp 397-419 (2021) (2021)
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Cognitive and environmental predictors of academic skills in French middle school students ; Prédicteurs cognitifs et environnementaux des apprentissages scolaires chez les élèves de collège en France
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In: https://tel.archives-ouvertes.fr/tel-03375054 ; Psychology. Sorbonne Université, 2020. English. ⟨NNT : 2020SORUS240⟩ (2020)
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Expressive language development in adolescents with Down syndrome and fragile X syndrome: change over time and the role of family-related factors.
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In: Journal of neurodevelopmental disorders, vol 12, iss 1 (2020)
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Comparing two facets of emotion perception across multiple neurodegenerative diseases.
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In: Social cognitive and affective neuroscience, vol 15, iss 5 (2020)
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Amount and delay insensitivity during intertemporal choice in three neurodegenerative diseases reflects dorsomedial prefrontal atrophy.
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Beagle, Alexander J; Zahir, Ali; Borzello, Mia; Kayser, Andrew S; Hsu, Ming; Miller, Bruce L; Kramer, Joel H; Chiong, Winston. - : eScholarship, University of California, 2020
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Abstract:
Patients with Alzheimer's disease and other dementias often make poor financial decisions, but it remains unclear whether this reflects specific failures in decision-making or more general deficits in episodic and working memory. We investigated how patients with Alzheimer's disease, behavioral variant frontotemporal dementia (bvFTD), and semantic variant primary progressive aphasia (svPPA) apply information in an intertemporal choice task between smaller intermediate and larger delayed rewards, with minimal memory demands. Multilevel modeling estimated subject-level sensitivities to three attributes of choice (the relative difference in reward magnitude, delay length, and absolute reward magnitudes) as well as baseline impulsivity. While baseline impulsivity in patients with Alzheimer's disease did not differ from controls, patients with bvFTD and svPPA were more impulsive than controls overall. Patients with Alzheimer's disease or bvFTD were less sensitive than controls to all three choice attributes, whereas patients with svPPA were less sensitive than controls to two attributes. Attenuated sensitivity to information presented during the choice was associated across all subjects with dorsomedial prefrontal atrophy for all three choice attributes. Given the minimal memory demands of our task, these findings suggest specific mechanisms underlying decision-making failures beyond episodic and working memory deficits in dementia.
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Keyword:
2.1 Biological and endogenous factors; Acquired Cognitive Impairment; Aging; Alzheimer Disease; Alzheimer's disease; Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD); Aphasia; Atrophy; Behavioral and Social Science; Brain Disorders; Clinical Research; Cognitive Sciences; Delay discounting; Dementia; Experimental Psychology; Frontotemporal Dementia; Humans; Intertemporal decision making; Neurodegenerative; Neurodegenerative Diseases; Neuroeconomics; Neurological; Neurosciences; Primary Progressive; Psychology
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URL: https://escholarship.org/uc/item/6b27153v
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