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Cortical microstructure in primary progressive aphasia: a multicenter study.
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In: Alzheimer's research & therapy, vol 14, iss 1 (2022)
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Diminished preparatory physiological responses in frontotemporal lobar degeneration syndromes
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In: Brain Commun (2022)
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Uniform data set language measures for bvFTD and PPA diagnosis and monitoring.
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In: Alzheimer's & dementia (Amsterdam, Netherlands), vol 13, iss 1 (2021)
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Uniform data set language measures for bvFTD and PPA diagnosis and monitoring.
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In: Alzheimer's & dementia (Amsterdam, Netherlands), vol 13, iss 1 (2021)
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Uniform data set language measures for bvFTD and PPA diagnosis and monitoring
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Staffaroni, Adam M.; Weintraub, Sandra; Rascovsky, Katya; Rankin, Katherine P.; Taylor, Jack; Fields, Julie A.; Casaletto, Kaitlin B.; Hillis, Argye E.; Lukic, Sladjana; Gorno‐Tempini, Maria Luisa; Heuer, Hilary; Teylan, Merilee A.; Kukull, Walter A.; Miller, Bruce L.; Boeve, Bradley F.; Rosen, Howard J.; Boxer, Adam L.; Kramer, Joel H.
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In: Alzheimers Dement (Amst) (2021)
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Abstract:
INTRODUCTION: The Frontotemporal Lobar Degeneration Module (FTLD‐MOD) includes a neuropsychological battery designed to assess the clinical features of FTLD, although much is unknown about its utility. We investigated FTLD‐MOD and Uniform Data Set 3.0 (UDS) language tests for differential diagnosis and disease monitoring. METHODS: Linear regressions compared baseline performances in 1655 National Alzheimer's Coordinating Center participants (behavioral variant frontotemporal dementia (bvFTD, n = 612), semantic variant primary progressive aphasia (svPPA, n = 168), non‐fluent/agrammatic variant PPA (nfvPPA, n = 168), logopenic variant PPA (lvPPA, n = 109), and controls (n = 581)). Sample sizes to detect treatment effects were estimated using longitudinal data. RESULTS: Among PPAs, the FTLD‐MOD language tasks and UDS Multilingual Naming Test accurately discriminated svPPA. Number Span Forward best discriminated lvPPA; Phonemic:Semantic Fluency ratio was excellent for nfvPPA classification. UDS fluency and naming measures required the smallest sample size to detect meaningful change. DISCUSSION: The FTLD‐MOD and UDS differentiated among PPA subtypes. UDS 3.0 measures performed best for longitudinal monitoring.
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Keyword:
Cognitive & Behavioral Assessment
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URL: https://doi.org/10.1002/dad2.12148
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7896637/
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Association of APOE4 and Clinical Variability in Alzheimer Disease With the Pattern of Tau- and Amyloid-PET
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In: Neurology (2021)
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Hearing loss prevalence and years lived with disability, 1990–2019 : findings from the Global Burden of Disease Study 2019
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Comparing two facets of emotion perception across multiple neurodegenerative diseases.
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In: Social cognitive and affective neuroscience, vol 15, iss 5 (2020)
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Depressive Symptom Profiles Predict Specific Neurodegenerative Disease Syndromes in Early Stages.
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Utility of the global CDR® plus NACC FTLD rating and development of scoring rules: Data from the ARTFL/LEFFTDS Consortium.
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In: Alzheimer's & dementia : the journal of the Alzheimer's Association, vol 16, iss 1 (2020)
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| 11 |
Depressive Symptom Profiles Predict Specific Neurodegenerative Disease Syndromes in Early Stages.
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Utility of the global CDR® plus NACC FTLD rating and development of scoring rules: Data from the ARTFL/LEFFTDS Consortium.
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In: Alzheimer's & dementia : the journal of the Alzheimer's Association, vol 16, iss 1 (2020)
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Comparing two facets of emotion perception across multiple neurodegenerative diseases.
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In: Social cognitive and affective neuroscience, vol 15, iss 5 (2020)
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| 14 |
Utility of the global CDR® plus NACC FTLD rating and development of scoring rules: Data from the ARTFL/LEFFTDS Consortium
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In: Alzheimers Dement (2020)
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Longitudinal structural and metabolic changes in frontotemporal dementia
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In: Neurology (2020)
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Comparing two facets of emotion perception across multiple neurodegenerative diseases
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In: Soc Cogn Affect Neurosci (2020)
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| 17 |
Depressive Symptom Profiles Predict Specific Neurodegenerative Disease Syndromes in Early Stages
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In: Front Neurol (2020)
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Deformation-based shape analysis of the hippocampus in the semantic variant of primary progressive aphasia and Alzheimer’s disease
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Thalamo-cortical network hyperconnectivity in preclinical progranulin mutation carriers.
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Thalamo-cortical network hyperconnectivity in preclinical progranulin mutation carriers.
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In: Lee, Suzee E; Sias, Ana C; Kosik, Eena L; Flagan, Taru M; Deng, Jersey; Chu, Stephanie A; et al.(2019). Thalamo-cortical network hyperconnectivity in preclinical progranulin mutation carriers. NeuroImage. Clinical, 22, 101751. doi:10.1016/j.nicl.2019.101751. UCLA: Retrieved from: http://www.escholarship.org/uc/item/6vv8g8qt (2019)
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