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Test of a motor theory of long-term auditory memory.
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In: Proc Natl Acad Sci U S A , 109 (18) 7121 - 7125. (2012) (2012)
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| 2 |
Role of cerebellum in fine speech control in childhood: Persistent dysarthria after surgical treatment for posterior fossa tumour
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Role of cerebellum in fine speech control in childhood: Persistent dysarthria after surgical treatment for posterior fossa tumour
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In: BRAIN LANG , 117 (2) 69 - 76. (2011) (2011)
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Endophenotypes of FOXP2: Dysfunction within the human articulatory network
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In: EUR J PAEDIATR NEURO , 15 (4) 283 - 288. (2011) (2011)
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Speech and oral motor profile after childhood hemispherectomy
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Abstract:
Hemispherectomy (disconnection or removal of an entire cerebral hemisphere) is a rare surgical procedure used for the relief of drug-resistant epilepsy in children. After hemispherectomy, contralateral hemiplegia persists whereas gross expressive and receptive language functions can be remarkably spared. Motor speech deficits have rarely been examined systematically, thus limiting the accuracy of postoperative prognosis. We describe the speech profiles of hemispherectomized participants characterizing their intelligibility, articulation, phonological speech errors, dysarthric features, and execution and sequencing of orofacial speech and non-speech movements. Thirteen participants who had undergone hemispherectomy (six left, seven right; nine with congenital, four with acquired hemiplegia; operated between four months and 13 years) were investigated. Results showed that all participants were intelligible but showed a mild dysarthric profile characterized by neuromuscular asymmetry and reduced quality and coordination of movements, features that are characteristic of adult-onset unilateral upper motor neuron dysarthria, flaccid-ataxic variant. In addition, one left and four right hemispherectomy cases presented with impaired production of speech and non-speech sequences. No participant showed evidence of verbal or oral dyspraxia. It is concluded that mild dysarthria is persistent after left or right hemispherectomy, irrespective of age at onset of hemiplegia. These results indicate incomplete functional re-organization for the control of fine speech motor movements throughout childhood, and provide no evidence of hemispheric differences.
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URL: https://doi.org/10.1016/j.bandl.2009.12.004
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000280975600008&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=d4d813f4571fa7d6246bdc0dfeca3a1c
http://hdl.handle.net/11343/221228
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| 6 |
Speech and oral motor profile after childhood hemispherectomy
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| 7 |
Is the hippocampus necessary for visual and verbal binding in working memory?
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In: NEUROPSYCHOLOGIA , 48 (4) 1089 - 1095. (2010) (2010)
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| 8 |
Speech and oral motor profile after childhood hemispherectomy
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In: BRAIN LANG , 114 (2) 126 - 134. (2010) (2010)
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| 9 |
Speaking with a single cerebral hemisphere: fMRI language organization after hemispherectomy in childhood
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In: BRAIN LANG , 106 (3) 195 - 203. (2008) (2008)
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| 10 |
Cortical abnormalities and language function in young patients with basal ganglia stroke
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In: NEUROIMAGE , 36 (2) 431 - 440. (2007) (2007)
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| 11 |
Identification of FOXP2 truncation as a novel cause of developmental speech and language deficits.
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In: Symplectic Elements at Oxford ; Europe PubMed Central ; PubMed (http://www.ncbi.nlm.nih.gov/pubmed/) ; Web of Science (Lite) (http://apps.webofknowledge.com/summary.do) ; Scopus (http://www.scopus.com/home.url) ; CrossRef (2005)
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| 12 |
Identification of FOXP2 truncation as a novel cause of developmental speech and language deficits
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In: American Journal of Human Genetics , 76 (6) pp. 1074-1080. (2005) (2005)
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| 13 |
Identification of FOXP2 truncation as a novel cause of developmental speech and language deficits
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In: AM J HUM GENET , 76 (6) 1074 - 1080. (2005) (2005)
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| 14 |
Identification of FOXP2 Truncation as a novel cause of developmental speech and language deficits
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In: American Journal of Human Genetics , 76 (6) pp.1074 - 1080. (2005) (2005)
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| 15 |
Language reorganization in children with early-onset lesions of the left hemisphere: an fMRI study
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In: BRAIN , 127 1229 - 1236. (2004) (2004)
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Cortical lateralization during verb generation: a combined ERP and fMRI study
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In: NEUROIMAGE , 22 (2) 665 - 675. (2004) (2004)
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Functional MRI abnormalities during covert speech associated with FOXP2 gene mutation
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In: Nature Neuroscience , 6 (11 ) pp.1230 - 1237 . (2003) (2003)
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Language fMRI abnormalities associated with FOXP2 gene mutation
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In: NAT NEUROSCI , 6 (11) 1230 - 1237. (2003) (2003)
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Behavioural analysis of an inherited speech and language disorder: comparison with acquired aphasia
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Behavioural analysis of an inherited speech and language disorder: comparison with acquired aphasia.
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In: Symplectic Elements at Oxford ; Europe PubMed Central ; PubMed (http://www.ncbi.nlm.nih.gov/pubmed/) ; Web of Science (Lite) (http://apps.webofknowledge.com/summary.do) ; Scopus (http://www.scopus.com/home.url) ; CrossRef (2002)
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