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Advancements in Oncology with Artificial Intelligence—A Review Article
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In: Cancers; Volume 14; Issue 5; Pages: 1349 (2022)
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Management and Outcome of Young Women (≤40 Years) with Breast Cancer in Switzerland
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In: Cancers; Volume 14; Issue 5; Pages: 1328 (2022)
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Metaphors of cancer in the Arabic language: An analysis of the use of metaphors in the online narratives of breast cancer patients
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In: Open Linguistics, Vol 8, Iss 1, Pp 27-45 (2022) (2022)
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Assessment of the Relevance of a Breast Cancer Rehabilitation Program based on a Neutrosophic Linguistic Scale ...
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Assessment of the Relevance of a Breast Cancer Rehabilitation Program based on a Neutrosophic Linguistic Scale ...
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Assessment of the Relevance of a Breast Cancer Rehabilitation Program based on a Neutrosophic Linguistic Scale ...
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Assessment of the Relevance of a Breast Cancer Rehabilitation Program based on a Neutrosophic Linguistic Scale ...
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Incorporating the Breast Imaging Reporting and Data System Lexicon with a Fully Convolutional Network for Malignancy Detection on Breast Ultrasound
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In: Diagnostics; Volume 12; Issue 1; Pages: 66 (2021)
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Assessing PD-L1 Expression Status Using Radiomic Features from Contrast-Enhanced Breast MRI in Breast Cancer Patients: Initial Results
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In: Cancers; Volume 13; Issue 24; Pages: 6273 (2021)
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Culture and breast cancer surgical decisions and experiences
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Characterization of circulating breast cancer cells with tumorigenic and metastatic capacity
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Koch, Claudia; Kuske, Andra; Joosse, Simon A.; Yigit, Gökhan; Sflomos, George; Thaler, Sonja; Smith, Daniel J.; Werner, Stefan; Borgmann, Kerstin; Gärtner, Sebastian; Mossahebi Mohammadi, Parinaz; Battista, Laura; Cayrefourcq, Laure; Altmüller, Janine; Salinas-Riester, Gabriela; Raithatha, Kaamini; Zibat, Arne; Goy, Yvonne; Ott, Leonie; Bartkowiak, Kai; Tan, Tuan Zea; Zhou, Qing; Speicher, Michael; Müller, Volkmar; Gorges, Tobias M.; Jücker, Manfred; Thiery, Jean-Paul; Brisken, Cathrin; Riethdorf, Sabine; Alix-Panabières, Catherine; Pantel, Klaus
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In: ISSN: 1757-4676 ; EISSN: 1757-4684 ; EMBO Molecular Medicine ; https://hal.archives-ouvertes.fr/hal-03602489 ; EMBO Molecular Medicine, Wiley Open Access, 2020, 12 (9), pp.e11908. ⟨10.15252/emmm.201911908⟩ (2020)
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Abstract:
International audience ; Functional studies giving insight into the biology of circulating tumor cells (CTCs) remain scarce due to the low frequency of CTCs and lack of appropriate models. Here, we describe the characterization of a novel CTC-derived breast cancer cell line, designated CTC-ITB-01, established from a patient with metastatic estrogen receptor-positive (ER+ ) breast cancer, resistant to endocrine therapy. CTC-ITB-01 remained ER+ in culture, and copy number alteration (CNA) profiling showed high concordance between CTC-ITB-01 and CTCs originally present in the patient with cancer at the time point of blood draw. RNA-sequencing data indicate that CTC-ITB-01 has a predominantly epithelial expression signature. Primary tumor and metastasis formation in an intraductal PDX mouse model mirrored the clinical progression of ER+ breast cancer. Downstream ER signaling was constitutively active in CTC-ITB-01 independent of ligand availability, and the CDK4/6 inhibitor Palbociclib strongly inhibited CTC-ITB-01 growth. Thus, we established a functional model that opens a new avenue to study CTC biology.
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Keyword:
[SDV.CAN]Life Sciences [q-bio]/Cancer; [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology; Breast cancer; Circulating; Circulating tumor cells; Functional studies; Liquid biopsy; MESH: Animals; MESH: Biomarkers; MESH: Breast Neoplasms; MESH: Carcinogenesis; MESH: DNA Copy Number Variations; MESH: Female; MESH: Humans; MESH: Mice; MESH: Neoplasm Metastasis; MESH: Neoplastic Cells; Metastasis; Tumor
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URL: https://hal.archives-ouvertes.fr/hal-03602489/document https://doi.org/10.15252/emmm.201911908 https://hal.archives-ouvertes.fr/hal-03602489/file/EMBO%20Mol%20Med%20-%202020%20-%20Koch%20-%20Characterization%20of%20circulating%20breast%20cancer%20cells%20with%20tumorigenic%20and%20metastatic%20capacity.pdf https://hal.archives-ouvertes.fr/hal-03602489
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Breast cancer patients' language use across four stages ...
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Pattern Recognition of Non-Mass Enhancements on Breast MRI – A Pictorial Review with Radiologic-Pathologic Correlation. ...
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Role of BD4BREAST in supporting the categorization of mammographic findings according to the BI-RADS mammographic lexicon ...
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Can MRI Biomarkers Predict Triple-Negative Breast Cancer?
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In: Diagnostics; Volume 10; Issue 12; Pages: 1090 (2020)
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Exploring Intimacy in Collaborative Photographic Narratives of Breast Cancer
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In: Humanities ; Volume 9 ; Issue 1 (2020)
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Using artificial intelligence to analyse and teach communication in healthcare
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In: Breast (2020)
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Genetic testing and eHealth usage among Deaf women.
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In: Journal of genetic counseling, vol 28, iss 5 (2019)
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