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How Autism Affects Speech Understanding in Multitalker Environments
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In: DTIC (2014)
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| 23 |
Development and Utility of Automatic Language Processing Technologies. Volume 2
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In: DTIC (2014)
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| 24 |
Biological Information Processing in Single Microtubules
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In: DTIC (2014)
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| 27 |
Cortical Signatures of Heard and Imagined Speech Envelopes
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In: DTIC (2013)
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| 28 |
How Autism Affects Speech Understanding in Multitalker Environments
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In: DTIC (2013)
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| 29 |
Computational Modeling of Emotions and Affect in Social-Cultural Interaction
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In: DTIC (2013)
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| 30 |
What's Wrong With Automatic Speech Recognition (ASR) and How Can We Fix It?
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In: DTIC (2013)
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| 31 |
A Submodularity Framework for Data Subset Selection
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In: DTIC (2013)
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| 32 |
KEYNOTE 2 : Rebuilding the Tower of Babel - Better Communication with Standards
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In: DTIC (2013)
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| 33 |
Role of Autism Susceptibility Gene, CNTNAP2, in Neural Circuitry for Vocal Communication
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In: DTIC (2013)
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Abstract:
Variants of the contactin associated protein-like 2 (Cntnap2) gene are risk factors for language-related disorders including autism spectrum disorder, specific language impairment, and stuttering. Songbirds are useful models for study of human speech disorders due to their shared capacity for vocal learning, which relies on similar cortico-basal ganglia circuitry and genetic factors. We investigated Cntnap2 protein expression in the brain of the zebra finch, a songbird species in which males, but not females, learn their courtship songs. We hypothesized that Cntnap2 has overlapping functions in vocal learning species, and expected to find protein expression in song-related areas of the zebra finch brain. We found that Cntnap2 protein is enriched in several song control regions relative to surrounding tissues, particularly within the adult male, but not female, robust nucleus of the arcopallium (RA), a cortical song control region analogous to human layer 5 primary motor cortex. The onset of this sexually dimorphic expression coincides with the onset of sensorimotor learning in developing males. Enrichment in male RA appears due to expression in projection neurons within the nucleus, as well as to additional expression in nerve terminals of cortical projections to RA from the lateral magnocellular nucleus of the nidopallium. Cntnap2 protein expression in zebra finch brain supports the hypothesis that this molecule affects neural connectivity critical for vocal learning across taxonomic classes. ; The original document contains color images.
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Keyword:
*MENTAL DISORDERS; *VOICE COMMUNICATIONS; ADULTS; Anatomy and Physiology; BRAIN; GENETICS; Linguistics; Medicine and Medical Research; MOTORS; NERVE CELLS; NERVOUS SYSTEM; ORDER DISORDER TRANSFORMATIONS; PROTEINS; Psychology; RISK; SHARING; SPEECH; TISSUES(BIOLOGY)
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URL: http://oai.dtic.mil/oai/oai?&verb=getRecord&metadataPrefix=html&identifier=ADA604001
http://www.dtic.mil/docs/citations/ADA604001
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| 34 |
Raummetaphern als Brücke zwischen Internetwahrnehmung und Internetkommunikation
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In: 04-4 ; sofia-Diskussionsbeiträge zur Institutionenanalyse ; 32 (2013)
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| 35 |
The Representation and Processing of Tense, Aspect & Voice across Verbal Elements in English
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In: DTIC (2012)
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| 36 |
A Spoken Dialogue System for Command and Control
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In: DTIC (2012)
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| 37 |
Distributed Estimation in Sensor Networks with Imperfect Model Information: An Adaptive Learning-Based Approach
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In: DTIC (2012)
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| 38 |
Speech Synthesis Using Perceptually Motivated Features
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In: DTIC (2012)
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| 40 |
Machine Recognition vs Human Recognition of Voices
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In: DTIC (2012)
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