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Three-dimensional vocal fold structural change due to implant insertion in medialization laryngoplasty.
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In: PloS one, vol 15, iss 1 (2020)
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Phonovibratory Influences from Offset to Onset in Repeated Phonation: A Study of Sung Gestures using High-Speed Digital Imaging
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Phonovibratory Influences from Offset to Onset in Repeated Phonation: A Study of Sung Gestures using High-Speed Digital Imaging ...
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Control of the glottal configuration in ex vivo human models: quantitative anatomy for clinical and experimental practices.
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In: Surgical and radiologic anatomy : SRA ; https://hal.archives-ouvertes.fr/hal-03550302 ; Surgical and radiologic anatomy : SRA, 2017, 39 (3), pp.257--262. ⟨10.1007/s00276-016-1738-2⟩ (2017)
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High-Resolution, Non-Invasive Imaging of Upper Vocal Tract Articulators Compatible with Human Brain Recordings.
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In: PloS one, vol 11, iss 3 (2016)
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Effects of Vocal Fold Nodules on Glottal Cycle Measurements Derived from High-Speed Videoendoscopy in Children
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In: Electrical and Computer Engineering Faculty Publications (2016)
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Lésions bénignes courantes des cordes vocales : critères diagnostiques et prise en charge [Common benign lesions of the vocal fold : diagnostic criteria and management]
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In: Revue medicale suisse, vol. 12, no. 533, pp. 1661-1664 (2016)
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Lesões de massa : sintomas vocais e repercussões na qualidade de vida em voz em pacientes de um serviço de otorrinolaringologia de referência da região sul do Brasil
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Gli3 and the developmental biology of the mammalian voice
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Abstract:
Vocal communication is essential to human behavior, but the developmental biology of the larynx is largely unexplored. Many human congenital syndromes present with laryngeal malformations as well as voice defects including Greig cephalopolysyndactyly (GCPS) patients (Sataloff et al., 1995; Papay & Arnold, 2002). GCPS is caused by null mutations and deletions in the Gli3 gene, a member of the hedgehog signaling pathway (Hui & Joyner, 1993; Johnson, 1967). Loss of Gli3 is often associated with catastrophic changes in neural crest-derived structures in face and skull (XXX). In this study, we aim to shed light on the development of the larynx, the origins of laryngeal tissues, and the role of Gli3 in the development of the neural crest-derived laryngeal components. Here we show that the thyroid cartilage and vocal ligament are derived from the neural crest whereas the other laryngeal cartilages and musculature are mesoderm-derived. We characterize molecular markers for various tissue types in the larynx including muscle, cartilage, neurons, and vocal ligament. We used the Gli3 null mouse to understand the role of Gli3 in laryngeal development and to better understand how congenital malformations of the larynx affect vocalizations. In Gli3 [superscript xt/xt] null embryos, we detected the increase of neural crest-derived vocal ligament tissue at the expense of the thyroarytenoid muscle and the glottic opening. Finally, we detected a vocal phenotype consisting of changes in bandwidth and amplitude when comparing Gli3 [superscript +/xt] pups and their wild type littermates. ; Cellular and Molecular Biology
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Keyword:
Elastin; Gli3; Larynx; Neural crest; Pup isolation calls; Ultrasonic vocalizations; Vocal cords; Vocal ligament
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URL: https://doi.org/10.15781/T2HQ3S45T http://hdl.handle.net/2152/47207
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Primate feedstock for the evolution of consonants.
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In: Trends in cognitive sciences, vol 18, iss 2 (2014)
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Microstructure characterization of a decellularized vocal fold scaffold for laryngeal tissue engineering.
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In: The Laryngoscope, vol 124, iss 8 (2014)
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O espectro médio de longo termo na pesquisa e na clínica fonoaudiológica.
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The diagnostic role of high-speed vocal fold vibratory imaging.
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In: Journal of voice : official journal of the Voice Foundation, vol 27, iss 5 (2013)
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Morphologic Differences in the Vocal Tract Resonance Cavities of Voice Professionals: An MRI-Based Study
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