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1
Investigating the effects of noise exposure on self-report, behavioral and electrophysiological indices of hearing damage in musicians with normal audiometric thresholds
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2
Extended high frequency hearing and speech perception implications in adults and children
In: Hear Res (2020)
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3
Effects of Age and Noise Exposure on Proxy Measures of Cochlear Synaptopathy
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4
Acoustic middle-ear-muscle-reflex thresholds in humans with normal audiograms:No relations to tinnitus, speech perception in noise, or noise exposure
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5
Timing Of Primary Surgery for cleft palate (TOPS): protocol for a randomised trial of palate surgery at 6 months versus 12 months of age
Shaw, William; Semb, Gunvor; Lohmander, Anette. - : BMJ Publishing Group, 2019
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6
Timing Of Primary Surgery for cleft palate (TOPS): protocol for a randomised trial of palate surgery at 6 months versus 12 months of age.
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7
Timing Of Primary Surgery for cleft palate (TOPS): protocol for a randomised trial of palate surgery at 6 months versus 12 months of age.
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8
Impaired speech perception in noise with a normal audiogram:No evidence for cochlear synaptopathy and no relation to lifetime noise exposure
Abstract: In rodents, noise exposure can destroy synapses between inner hair cells and auditory nerve fibers (“cochlear synaptopathy”) without causing hair cell loss. Noise-induced cochlear synaptopathy usually leaves cochlear thresholds unaltered, but is associated with long-term reductions in auditory brainstem response (ABR) amplitudes at medium-to-high sound levels. This pathophysiology has been suggested to degrade speech perception in noise (SPiN), perhaps explaining why SPiN ability varies so widely among audiometrically normal humans. The present study is the first to test for evidence of cochlear synaptopathy in humans with significant SPiN impairment. Individuals were recruited on the basis of self-reported SPiN difficulties and normal pure tone audiometric thresholds. Performance on a listening task identified a subset with “verified” SPiN impairment. This group was matched with controls on the basis of age, sex, and audiometric thresholds up to 14 kHz. ABRs and envelope-following responses (EFRs) were recorded at high stimulus levels, yielding both raw amplitude measures and within-subject difference measures. Past exposure to high sound levels was assessed by detailed structured interview. Impaired SPiN was not associated with greater lifetime noise exposure, nor with any electrophysiological measure. It is conceivable that retrospective self-report cannot reliably capture noise exposure, and that ABRs and EFRs offer limited sensitivity to synaptopathy in humans. Nevertheless, the results do not support the notion that noise-induced synaptopathy is a significant etiology of SPiN impairment with normal audiometric thresholds. It may be that synaptopathy alone does not have significant perceptual consequences, or is not widespread in humans with normal audiograms.
URL: https://doi.org/10.1016/j.heares.2018.03.008
https://eprints.lancs.ac.uk/id/eprint/123880/1/SPiN_difficulties_paper_for_Pure_pics_SM.pdf
https://eprints.lancs.ac.uk/id/eprint/123880/
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9
Impaired speech perception in noise with a normal audiogram: No evidence for cochlear synaptopathy and no relation to lifetime noise exposure
Guest, Hannah; Munro, Kevin J.; Prendergast, Garreth. - : Elsevier/North-Holland Biomedical Press, 2018
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10
No evidence for enhanced processing of speech that is low-pass filtered near the edge frequency of cochlear dead regions in children
Malicka, Alicja N.; Wilson, Wayne J.; Baer, Thomas. - : Taylor & Francis, 2018
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11
Tinnitus and sleep difficulties after cochlear implantation
Pierzycki, Robert H.; Edmondson-Jones, Mark; Dawes, Piers. - : Lippincott, Williams & Wilkins, 2016
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12
Effects of broadband noise on cortical evoked auditory responses at different loudness levels in young adults
Sharma, Mridula; Purdy, Suzanne C; Munro, Kevin J. - : Lippincott Williams and Wilkins, 2014
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13
The effect of low-pass filtering on identification of nonsense syllables in quiet by school-age children with and without cochlear dead regions
Malicka, Alicja N.; Munro, Kevin J.; Baer, Thomas. - : Lippincott Williams & Wilkins, 2013
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14
Listening effort at signal-to-noise ratios that are typical of the school classroom
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15
Reorganization of the Adult Auditory System: Perceptual and Physiological Evidence From Monaural Fitting of Hearing Aids
Munro, Kevin J.. - : SAGE Publications, 2008
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16
Reorganization of the Adult Auditory System: Perceptual and Physiological Evidence From Monaural Fitting of Hearing Aids
Munro, Kevin J.. - : SAGE Publications, 2008
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