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Semantic Feature Disturbance in Alzheimer Disease: Evidence from an Object Decision Task
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Alzheimer's disease is associated with distinctive semantic feature loss
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Lexical-semantic representation in bilingual aphasia: Findings from semantic priming and cognate repetition priming
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The Influence of Dopamine on Automatic and Controlled Semantic Activation in Parkinson's Disease
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Effect of aging on learning new names and descriptions for objects
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The influence of dopamine on automatic and controlled semantic activation in Parkinson's disease.
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Investigation of the non-markovity spectrum as a cognitive processing measure of deep brain microelectrode recordings
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Decreased semantic competitive inhibition in Parkinson's disease: Evidence from an investigation of word search performance
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Bilingualism and aging: reversal of the cognate advantage on older bilingual adults
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Semantic activation in Parkinson's disease patients on and off levodopa
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Abstract:
Research suggests that dopamine may exert a neuromodulatory influence on automatic spreading activation within semantic networks. In order to investigate the influence of dopamine depletion on semantic activation in Parkinson's disease (PD), nine patients with PD performed a lexical decision task when on and off levodopa medication. Eleven healthy controls matched to the PD patients in terms of sex, age and education also participated in the study. Both directly related word pairs (e.g., tiger - stripe) and indirectly related word pairs (word pairs related via a mediating word, e.g., chalk - black) were used to measure semantic activation across stimulus onset asynchronies (SOAs) of 270 msec, 520 msec and 1020 msec. Analysis of variance statistics revealed that the activation of directly related and indirectly related targets was slower for the PD group relative to the control group. Within group comparisons revealed further changes to semantic activation in PD patients off medication, with no activation of directly or indirectly related target words evident in PD patients off medication. These results further clarify the nature of dopamine's neuromodulatory influence on semantic activation, and suggest that the nature of altered semantic activation in PD may depend on the magnitude of dopamine depletion. (C) 2009 Elsevier Srl. All rights reserved.
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Keyword:
170204 Linguistic Processes (incl. Speech Production and Comprehension); 920201 Allied Health Therapies (excl. Mental Health Services); Automatic spreading activation; C1; Dopamine; Language; Parkinson's disease; Semantic priming; Spreading activation
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URL: https://espace.library.uq.edu.au/view/UQ:180359
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Hemispheric contributions to semantic activation: A divided visual field and event-related potential investigation of time-course.
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Verbal fluency, semantics, context and symptom complexes in schizophrenia
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Bilingualism and aging: Reversal of the cognate advantage in older bilingual adults
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Impaired semantic inhibition during lexical ambiguity repetition in parkinson's disease
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The influence of aging and aphasia on bilingual semantic organization
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