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Uniform data set language measures for bvFTD and PPA diagnosis and monitoring.
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In: Alzheimer's & dementia (Amsterdam, Netherlands), vol 13, iss 1 (2021)
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Uniform data set language measures for bvFTD and PPA diagnosis and monitoring.
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In: Alzheimer's & dementia (Amsterdam, Netherlands), vol 13, iss 1 (2021)
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German Language Adaptation of the NAVS (NAVS-G) and of the NAT (NAT-G): Testing Grammar in Aphasia
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In: Brain Sci (2021)
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Uniform data set language measures for bvFTD and PPA diagnosis and monitoring
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In: Alzheimers Dement (Amst) (2021)
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German language adaptation of the NAVS (NAVS-G) and of the NAT (NAT-G): testing grammar in aphasia
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In: Brain sciences. - 11, 4 (2021) , 474, ISSN: 2076-3425 (2021)
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Utility of the global CDR® plus NACC FTLD rating and development of scoring rules: Data from the ARTFL/LEFFTDS Consortium.
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In: Alzheimer's & dementia : the journal of the Alzheimer's Association, vol 16, iss 1 (2020)
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Utility of the global CDR® plus NACC FTLD rating and development of scoring rules: Data from the ARTFL/LEFFTDS Consortium.
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In: Alzheimer's & dementia : the journal of the Alzheimer's Association, vol 16, iss 1 (2020)
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Data from: ApoE is a correlate of phenotypic heterogeneity in Alzheimer’s disease in a national cohort ...
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Utility of the global CDR® plus NACC FTLD rating and development of scoring rules: Data from the ARTFL/LEFFTDS Consortium
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In: Alzheimers Dement (2020)
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APOE is a correlate of phenotypic heterogeneity in Alzheimer disease in a national cohort
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In: Neurology (2020)
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Measurement and characterization of distinctive clinical phenotypes using the Frontotemporal Lobar Degeneration Module (FTLD-MOD)
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In: Alzheimers Dement (2020)
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Familial language network vulnerability in primary progressive aphasia
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In: Neurology (2020)
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Montreal Cognitive Assessment (MoCA) Performance and Domain-Specific Index Scores in Amnestic versus Aphasic Dementia
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In: J Int Neuropsychol Soc (2020)
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Abstract:
OBJECTIVE: The Montreal Cognitive Assessment (MoCA) is a popular and simple-to-administer screening instrument to detect cognitive impairment. The MoCA generates a total score and six domain-specific index scores: (1) Memory, (2) Executive Functioning, (3) Attention, (4) Language, (5) Visuospatial, and (6) Orientation. It is unclear whether these MoCA scores can differentiate between distinct clinical dementia syndromes. This study compared MoCA Index scores between amnestic dementia of the Alzheimer’s type (DAT) and primary progressive aphasia (PPA), a language-based dementia. METHOD: Baseline MoCA data were analyzed from 33 DAT, 37 PPA, and 83 cognitively normal individuals enrolled in the Clinical Core of the Northwestern Alzheimer’s Disease Center. A one-way analysis of covariance adjusted for age was used to compare MoCA scores among groups. A logistic regression model was implemented to observe individual likelihood of group affiliation based on MoCA Index scores. RESULTS: The mean MoCA total score was significantly higher in controls compared to both patient groups (p < .001) but did not differ between DAT and PPA groups. However, in accordance with salient clinical features commonly observed in DAT versus PPA, Memory and Orientation Index scores were lowest in the DAT group (p < .001), whereas Language and Attention Index scores were lowest in the PPA group (p < .001). Multivariate logistic regression analysis showed that the individual effects of Memory (p = .001), Language (p = .002), and Orientation (p = .025) Indices were significant. CONCLUSIONS: MoCA Index scores can help differentiate among distinct cognitive syndromes, suggesting it may be a useful brief screening tool to detect domain-specific cognitive impairment.
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Article
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URL: https://doi.org/10.1017/S135561772000048X
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554137/
http://www.ncbi.nlm.nih.gov/pubmed/32423505
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Genetic screen in a large series of patients with primary progressive aphasia
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PREFERENTIAL DISRUPTION OF AUDITORY WORD REPRESENTATIONS IN PRIMARY PROGRESSIVE APHASIA WITH THE NEUROPATHOLOGY OF FTLD-TDP TYPE A
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Northwestern Anagram Test-Italian (Nat-I) for primary progressive aphasia
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In: Cortex (2019)
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Clinical and cortical decline in the aphasic variant of Alzheimer’s disease
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Neuropathologic basis of in vivo cortical atrophy in the aphasic variant of Alzheimer’s disease
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In: Brain Pathol (2019)
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Word comprehension in temporal cortex and Wernicke area: A PPA perspective
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Morphology and Distribution of TDP-43 Pre-inclusions in Primary Progressive Aphasia
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