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Surnames in south-eastern France: structure of the rural population during the 19th century through isonymy
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In: ISSN: 0021-9320 ; EISSN: 1469-7599 ; Journal of Biosocial Science ; https://hal.archives-ouvertes.fr/hal-03521816 ; Journal of Biosocial Science, Cambridge University Press (CUP), In press, ⟨10.1017/S0021932021000699⟩ (2022)
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Genome-wide diversity and demographic dynamics of Cameroon goats and their divergence from east African, north African, and Asian conspecifics
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Radical Social Ecology as Deep Pragmatism: A Call to the Abolition of Systemic Dissonance and the Minimization of Entropic Chaos
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In: Student Theses 2015-Present (2018)
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Regional gray matter correlates of memory for emotion-laden words in middle-aged and older adults: A voxel-based morphometry study
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Reconstructing Social Prehistory from Genomic Data in the Indo-Pacific Region
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Fine-Scale Human Population Structure in Southern Africa Reflects Ecogeographic Boundaries.
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In: Genetics, vol 204, iss 1 (2016)
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Developing and Pilot Testing a Spanish Translation of CollaboRATE for Use in the United States
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| 8 |
Auditory-Motor Mapping Training: Comparing the Effects of a Novel Speech Treatment to a Control Treatment for Minimally Verbal Children with Autism
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Revisiting the Diego Blood Group System in Amerindians: Evidence for Gene-Culture Comigration
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In: ISSN: 1932-6203 ; EISSN: 1932-6203 ; PLoS ONE ; https://hal-amu.archives-ouvertes.fr/hal-01199829 ; PLoS ONE, Public Library of Science, 2015, pp.e0132211. ⟨10.1371/journal.pone.0132211⟩ (2015)
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| 11 |
Getting the most from a surname study: semantics, DNA and computer modelling (third edition)
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| 12 |
Balancing Selection on a Regulatory Region Exhibiting Ancient Variation That Predates Human–Neandertal Divergence
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Gokcumen, Omer; Zhu, Qihui; Mulder, Lubbertus C. F.; Iskow, Rebecca C.; Austermann, Christian; Scharer, Christopher D.; Raj, Towfique; Boss, Jeremy M.; Sunyaev, Shamil R.; Price, Alkes; Stranger, Barbara; Simon, Viviana; Lee, Charles. - : Public Library of Science, 2013
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Abstract:
Ancient population structure shaping contemporary genetic variation has been recently appreciated and has important implications regarding our understanding of the structure of modern human genomes. We identified a ∼36-kb DNA segment in the human genome that displays an ancient substructure. The variation at this locus exists primarily as two highly divergent haplogroups. One of these haplogroups (the NE1 haplogroup) aligns with the Neandertal haplotype and contains a 4.6-kb deletion polymorphism in perfect linkage disequilibrium with 12 single nucleotide polymorphisms (SNPs) across diverse populations. The other haplogroup, which does not contain the 4.6-kb deletion, aligns with the chimpanzee haplotype and is likely ancestral. Africans have higher overall pairwise differences with the Neandertal haplotype than Eurasians do for this NE1 locus (p<10−15). Moreover, the nucleotide diversity at this locus is higher in Eurasians than in Africans. These results mimic signatures of recent Neandertal admixture contributing to this locus. However, an in-depth assessment of the variation in this region across multiple populations reveals that African NE1 haplotypes, albeit rare, harbor more sequence variation than NE1 haplotypes found in Europeans, indicating an ancient African origin of this haplogroup and refuting recent Neandertal admixture. Population genetic analyses of the SNPs within each of these haplogroups, along with genome-wide comparisons revealed significant FST (p = 0.00003) and positive Tajima's D (p = 0.00285) statistics, pointing to non-neutral evolution of this locus. The NE1 locus harbors no protein-coding genes, but contains transcribed sequences as well as sequences with putative regulatory function based on bioinformatic predictions and in vitro experiments. We postulate that the variation observed at this locus predates Human–Neandertal divergence and is evolving under balancing selection, especially among European populations. ; Version of Record
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Keyword:
Biology; Evolutionary Biology; Genomics; Population Biology; Population Genetics
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URL: http://nrs.harvard.edu/urn-3:HUL.InstRepos:11235975
https://doi.org/10.1371/journal.pgen.1003404
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| 14 |
Languages cool as they expand: allometric scaling and the decreasing need for new words
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| 15 |
Getting the most from a surname study: semantics, DNA and computer modelling
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| 16 |
Genomic ancestry of North Africans supports back-to-Africa migrations.
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In: PLoS genetics, vol 8, iss 1 (2012)
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You Name It – How Memory and Delay Govern First Name Dynamics
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Ancestry of the Iban is predominantly Southeast Asian: Genetic evidence from autosomal, mitochondrial, and Y chromosomes
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Graduate Committee Minutes
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In: Graduate Committee Minutes (2010)
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