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All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Page: 1 2 3 Hits 1 – 20 of 58 1 Digital Speech Analysis in Progressive Supranuclear Palsy and Corticobasal Syndromes Parjane, Natalia; Cho, Sunghye; Ash, Sharon... In: J Alzheimers Dis (2021) BASE Show details 2 Automated analysis of lexical features in Frontotemporal Degeneration Cho, Sunghye; Nevler, Naomi; Ash, Sharon... In: Cortex (2021) BASE Show details 3 Automated analysis of natural speech in amyotrophic lateral sclerosis spectrum disorders Nevler, Naomi; Ash, Sharon; McMillan, Corey... In: Neurology (2020) BASE Show details 4 Automated analysis of lexical features in Frontotemporal Degeneration Cho, Sunghye; Nevler, Naomi; Ash, Sharon; Shellikeri, Sanjana; Irwin, David J.; Massimo, Lauren; Rascovsky, Katya; Olm, Christopher; Grossman, Murray; Liberman, Mark In: medRxiv (2020) Abstract: We implemented an automated analysis of lexical aspects of semi-structured speech produced by healthy elderly controls (n=37) and three patient groups with frontotemporal degeneration (FTD): behavioral variant FTD (n=74), semantic variant primary progressive aphasia (svPPA, n=42), and nonfluent/agrammatic PPA (naPPA, n=22). Based on previous findings, we hypothesized that the three patient groups and controls would differ in the counts of part-of-speech (POS) categories and several lexical measures. With a natural language processing program, we automatically tagged POS categories of all words produced during a picture description task. We further counted the number of wh-words, and we rated nouns for abstractness, ambiguity, frequency, familiarity, and age of acquisition. We also computed the cross-entropy estimation, which is a measure of word predictability, and lexical diversity for each description. We validated a subset of the POS data that were automatically tagged with the Google Universal POS scheme using gold-standard POS data tagged by a linguist, and we found that the POS categories from our automated methods were more than 90% accurate. For svPPA patients, we found fewer unique nouns than in naPPA and more pronouns and wh-words than in the other groups. We also found high abstractness, ambiguity, frequency, and familiarity for nouns and the lowest cross-entropy estimation among all groups. These measures were associated with cortical thinning in the left temporal lobe. In naPPA patients, we found increased speech errors and partial words compared to controls, and these impairments were associated with cortical thinning in the left middle frontal gyrus. bvFTD patients’ adjective production was decreased compared to controls and was correlated with their apathy scores. Their adjective production was associated with cortical thinning in the dorsolateral frontal and orbitofrontal gyri. Our results demonstrate distinct language profiles in subgroups of FTD patients and validate our automated method of analyzing FTD patients’ speech. Keyword: Article URL: http://www.ncbi.nlm.nih.gov/pubmed/33173922 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7654918/ https://doi.org/10.1101/2020.09.10.20192054 BASE Hide details 5 A Longitudinal Study of Speech Production in Primary Progressive Aphasia and Behavioral Variant Frontotemporal Dementia Ash, Sharon; Nevler, Naomi; Phillips, Jeffrey... In: Brain Lang (2019) BASE Show details 6 Linguistic markers in Parkinson’s disease (Smith et al., 2018) ... Smith, Kara M.; Ash, Sharon; Xie, Sharon X.. - : Figshare, 2018 BASE Show details 7 Linguistic markers in Parkinson’s disease (Smith et al., 2018) ... Smith, Kara M.; Ash, Sharon; Xie, Sharon X.. - : ASHA journals, 2018 BASE Show details 8 Validated automatic speech biomarkers in primary progressive aphasia Nevler, Naomi; Ash, Sharon; Irwin, David J. - : John Wiley and Sons Inc., 2018 BASE Show details 9 Longitudinal Changes in Semantic Concreteness in Semantic Variant Primary Progressive Aphasia (svPPA) Cousins, Katheryn A. Q.; Ash, Sharon; Olm, Christopher A.. - : Society for Neuroscience, 2018 BASE Show details 10 Evaluation of Linguistic Markers of Word-Finding Difficulty and Cognition in Parkinson's Disease Smith, Kara M.; Ash, Sharon; Xie, Sharon X.. - : American Speech-Language-Hearing Association, 2018 BASE Show details 11 Clinical marker for Alzheimer disease pathology in logopenic primary progressive aphasia Giannini, Lucia A.A.; Irwin, David J.; McMillan, Corey T.. - : Lippincott Williams & Wilkins, 2017 BASE Show details 12 Longitudinal decline in speech production in Parkinson's disease spectrum disorders Ash, Sharon; Jester, Charles; York, Collin. - 2017 BASE Show details 13 Transcranial direct current stimulation for the treatment of primary progressive aphasia: An open-label pilot study Gervits, Felix; Ash, Sharon; Coslett, H. Branch. - 2016 BASE Show details 14 Dissociation of Quantifiers and Object Nouns in Speech in Focal Neurodegenerative Disease Ash, Sharon; Ternes, Kylie; Bisbing, Teagan. - 2016 BASE Show details 15 Dissociable substrates underlie the production of abstract and concrete nouns Cousins, Katheryn AQ; Ash, Sharon; Irwin, David J. - 2016 BASE Show details 16 Why study connected speech production? Ash, Sharon; Grossman, Murray In: Cognitive neuroscience of natural language use (Cambridge, 2015), p. 29-58 MPI für Psycholinguistik Show details 17 Why study connected speech production? Ash, Sharon; Grossman, Murray In: Cognitive neuroscience of natural language use (Cambridge, 2015), p. 29-58 MPI für Psycholinguistik Show details 18 Deficits in sentence expression in amyotrophic lateral sclerosis Ash, Sharon; Olm, Christopher; Mcmillan, Corey T.. - 2014 BASE Show details 19 Differentiating primary progressive aphasias in a brief sample of connected speech Ash, Sharon; Evans, Emily; O'Shea, Jessica. - : Lippincott Williams & Wilkins, 2013 BASE Show details 20 Grammatical comprehension deficits in non-fluent/agrammatic primary progressive aphasia Charles, Dorothy; Olm, Christopher; Powers, John. - 2013 BASE Show details Page: 1 2 3

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