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Polygenic scores for intelligence, educational attainment and schizophrenia are differentially associated with core autism features, IQ, and adaptive behaviour in autistic individuals
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In: https://hal-pasteur.archives-ouvertes.fr/pasteur-03261146 ; 2021 (2021)
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Atypical Brain Asymmetry in Autism-A Candidate for Clinically Meaningful Stratification
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In: Floris, Dorothea L; Wolfers, Thomas; Zabihi, Mariam; Holz, Nathalie E; Zwiers, Marcel P; Charman, Tony; Tillmann, Julian; Ecker, Christine; Dell'Acqua, Flavio; Banaschewski, Tobias; Moessnang, Carolin; Baron-Cohen, Simon; Holt, Rosemary; Durston, Sarah; Loth, Eva; Murphy, Declan G M; Marquand, Andre; Buitelaar, Jan K; Beckmann, Christian F; EU-AIMS Longitudinal European Autism Project Group (2021). Atypical Brain Asymmetry in Autism-A Candidate for Clinically Meaningful Stratification. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 6(8):802-812. (2021)
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Face individual identity recognition: a potential endophenotype in autism
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In: Mol Autism (2020)
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Child, Maternal and Demographic Factors Influencing Caregiver-Reported Autistic Trait Symptomatology in Toddlers. ...
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Child, Maternal and Demographic Factors Influencing Caregiver-Reported Autistic Trait Symptomatology in Toddlers.
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Savant syndrome has a distinct psychological profile in autism
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A cross-cultural study of autistic traits across India, Japan and the UK
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Repetition suppression and memory for faces is reduced in adults with autism spectrum conditions
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Repetition Suppression and Memory for Faces is Reduced in Adults with Autism Spectrum Conditions
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Early development of infants with neurofibromatosis type 1: A case series
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Randomised trial of a parent-mediated intervention for infants at high risk for autism: longitudinal outcomes to age 3 years
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Basic and complex emotion recognition in children with autism: cross-cultural findings
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Reduced Volume of the Arcuate Fasciculus in Adults with High-Functioning Autism Spectrum Conditions ...
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Reduced Volume of the Arcuate Fasciculus in Adults with High-Functioning Autism Spectrum Conditions
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Lost for emotion words: What motor and limbic brain activity reveals about autism and semantic theory
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Abstract:
Autism spectrum conditions (ASC) are characterised by deficits in understanding and expressing emotions and are frequently accompanied by alexithymia, a difficulty in understanding and expressing emotion words. Words are differentially represented in the brain according to their semantic category and these difficulties in ASC predict reduced activation to emotion-related words in limbic structures crucial for affective processing. Semantic theories view ‘emotion actions’ as critical for learning the semantic relationship between a word and the emotion it describes, such that emotion words typically activate the cortical motor systems involved in expressing emotion actions such as facial expressions. As ASC are also characterised by motor deficits and atypical brain structure and function in these regions, motor structures would also be expected to show reduced activation during emotion-semantic processing. Here we used event-related fMRI to compare passive processing of emotion words in comparison to abstract verbs and animal names in typically-developing controls and individuals with ASC. Relatively reduced brain activation in ASC for emotion words, but not matched control words, was found in motor areas and cingulate cortex specifically. The degree of activation evoked by emotion words in the motor system was also associated with the extent of autistic traits as revealed by the Autism Spectrum Quotient. We suggest that hypoactivation of motor and limbic regions for emotion word processing may underlie difficulties in processing emotional language in ASC. The role that sensorimotor systems and their connections might play in the affective and social-communication difficulties in ASC is discussed.
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URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265725 http://www.ncbi.nlm.nih.gov/pubmed/25278250 https://doi.org/10.1016/j.neuroimage.2014.09.046
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Neuroanatomy of Individual Differences in Language in Adult Males with Autism
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Neuroanatomy of Individual Differences in Language in Adult Males with Autism
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Lost for emotion words: what motor and limbic brain activity reveals about autism and semantic theory
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A pooled genome-wide association study of Asperger Syndrome
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Brain routes for reading in adults with and without autism: EMEG evidence
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