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A 'Mini Linguistic State Examination' to classify primary progressive aphasia. ...
Patel, Nikil; Peterson, Katie A; Ingram, Ruth U. - : Apollo - University of Cambridge Repository, 2022
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A 'Mini Linguistic State Examination' to classify primary progressive aphasia. ...
Patel, Nikil; Peterson, Katie A; Ingram, Ruth U. - : Apollo - University of Cambridge Repository, 2022
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3
Content Word Production during Discourse in Aphasia: Deficits in Word Quantity, Not Lexical-Semantic Complexity. ...
Alyahya, Reem SW; Halai, Ajay D; Conroy, Paul. - : Apollo - University of Cambridge Repository, 2021
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Content Word Production during Discourse in Aphasia: Deficits in Word Quantity, Not Lexical-Semantic Complexity.
Halai, Ajay D; Alyahya, Reem SW; Conroy, Paul. - : MIT Press - Journals, 2021. : Department of Psychiatry, 2021. : J Cogn Neurosci, 2021
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5
Graded, multidimensional intra- and intergroup variations in primary progressive aphasia and post-stroke aphasia.
In: Brain : a journal of neurology, vol 143, iss 10 (2020)
Abstract: Language impairments caused by stroke (post-stroke aphasia, PSA) and neurodegeneration (primary progressive aphasia, PPA) have overlapping symptomatology, nomenclature and are classically divided into categorical subtypes. Surprisingly, PPA and PSA have rarely been directly compared in detail. Rather, previous studies have compared certain subtypes (e.g. semantic variants) or have focused on a specific cognitive/linguistic task (e.g. reading). This study assessed a large range of linguistic and cognitive tasks across the full spectra of PSA and PPA. We applied varimax-rotated principal component analysis to explore the underlying structure of the variance in the assessment scores. Similar phonological, semantic and fluency-related components were found for PSA and PPA. A combined principal component analysis across the two aetiologies revealed graded intra- and intergroup variations on all four extracted components. Classification analysis was used to test, formally, whether there were any categorical boundaries for any subtypes of PPA or PSA. Semantic dementia formed a true diagnostic category (i.e. within group homogeneity and distinct between-group differences), whereas there was considerable overlap and graded variations within and between other subtypes of PPA and PSA. These results suggest that (i) a multidimensional rather than categorical classification system may be a better conceptualization of aphasia from both causes; and (ii) despite the very different types of pathology, these broad classes of aphasia have considerable features in common.
Keyword: 2.1 Biological and endogenous factors; Acquired Cognitive Impairment; Aged; Aging; Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD); Alzheimer's Disease Related Dementias (ADRD); Aphasia; Brain Disorders; classification; Clinical Research; Dementia; Female; Frontotemporal Dementia (FTD); Humans; Male; Medical and Health Sciences; Middle Aged; neurodegeneration; Neurodegenerative; Neurology & Neurosurgery; Neurosciences; Observer Variation; Phonetics; Primary Progressive; Principal Component Analysis; Psychology and Cognitive Sciences; Rare Diseases; Semantics; Stroke
URL: https://escholarship.org/uc/item/6r78p9jx
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6
A unified model of post-stroke language deficits including discourse production and their neural correlates. ...
Alyahya, Reem SW; Halai, Ajay; Conroy, Paul. - : Apollo - University of Cambridge Repository, 2020
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7
Evaluating the granularity and statistical structure of lesions and behaviour in post-stroke aphasia ...
Zhao, Ying; Lambon Ralph, Matthew; Halai, Ajay. - : Apollo - University of Cambridge Repository, 2020
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8
The verbal, nonverbal and structural bases of functional communication abilities in aphasia ...
Schmacher, Rahel; Bruehl, Stefanie; Halai, Ajay. - : Apollo - University of Cambridge Repository, 2020
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9
Graded, multidimensional intra- and intergroup variations in primary progressive aphasia and post-stroke aphasia. ...
Ingram, Ruth U; Halai, Ajay; Pobric, Gorana. - : Apollo - University of Cambridge Repository, 2020
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10
The verbal, non-verbal and structural bases of functional communication abilities in aphasia ...
Schumacher, Rahel; Bruehl, Stefanie; Halai, Ajay D. - : Oxford University Press, 2020
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11
Graded, multidimensional intra- and intergroup variations in primary progressive aphasia and post-stroke aphasia.
Ingram, Ruth U; Halai, Ajay; Pobric, Gorana. - : Oxford University Press (OUP), 2020. : Brain, 2020
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12
Evaluating the granularity and statistical structure of lesions and behaviour in post-stroke aphasia
Zhao, Ying; Lambon Ralph, Matthew; Halai, Ajay. - : Oxford University Press (OUP), 2020. : Brain Communications, 2020
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13
A unified model of post-stroke language deficits including discourse production and their neural correlates.
Conroy, Paul; Halai, Ajay; Alyahya, Reem SW. - : Oxford University Press (OUP), 2020. : Brain, 2020
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14
The verbal, nonverbal and structural bases of functional communication abilities in aphasia
Halai, Ajay; Schmacher, Rahel; Lambon Ralph, Matthew. - : Oxford University Press (OUP), 2020. : Brain Communications, 2020
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15
Investigating the effect of changing parameters when building prediction models in post-stroke aphasia
In: Nat Hum Behav (2020)
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16
The verbal, non-verbal and structural bases of functional communication abilities in aphasia
In: Brain Commun (2020)
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17
Evaluating the granularity and statistical structure of lesions and behaviour in post-stroke aphasia
In: Brain Commun (2020)
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18
A unified model of post-stroke language deficits including discourse production and their neural correlates
In: Brain (2020)
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19
Assessing and mapping language, attention and executive multidimensional deficits in stroke aphasia. ...
Schumacher, Rahel; Halai, Ajay; Lambon Ralph, Matthew. - : Apollo - University of Cambridge Repository, 2019
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20
Assessing and mapping language, attention and executive multidimensional deficits in stroke aphasia ...
Schumacher, Rahel; Halai, Ajay D; Lambon Ralph, Matthew A. - : Oxford University Press, 2019
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