1 |
Functional connectivity in the developing language network in 4-year-old children predicts future reading ability
|
|
|
|
In: Dev Sci (2020)
|
|
BASE
|
|
Show details
|
|
2 |
From BDNF to Reading: Neural Activation and Phonological Processing as Multiple Mediators
|
|
|
|
In: Behav Brain Res (2020)
|
|
Abstract:
The BDNF gene is a prominent promoter of neuronal development, maturation and plasticity. Its Val(66)Met polymorphism affects brain morphology and function within several areas and is associated with several cognitive functions and neurodevelopmental disorder susceptibility. Recently, it has been associated with reading, reading-related traits and altered neural activation in reading–related brain regions. However, it remains unknown if the intermediate phenotypes (IPs, such as brain activation and phonological skills) mediate the pathway from gene to reading or reading disability. By conducting a serial multiple mediation model in a sample of 94 children (age 5–13), our findings revealed no direct effects of genotype on reading. Instead, we found that genotype is associated with brain activation in reading-related and more domain general regions which in turn is associated with phonological processing which is associated with reading. These findings suggest that the BDNF-Val(66)Met polymorphism is related to reading via phonological processing and functional activation. These results support brain imaging data and neurocognitive traits as viable IPs for complex behaviors.
|
|
Keyword:
Article
|
|
URL: http://www.ncbi.nlm.nih.gov/pubmed/32810467 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7572787/ https://doi.org/10.1016/j.bbr.2020.112859
|
|
BASE
|
|
Hide details
|
|
3 |
Common variation within the SETBP1 gene is associated with reading-related skills and patterns of functional neural activation
|
|
|
|
In: Neuropsychologia (2018)
|
|
BASE
|
|
Show details
|
|
4 |
Neuroimaging Field Methods Using Functional Near Infrared Spectroscopy (NIRS) Neuroimaging to Study Global Child Development: Rural Sub-Saharan Africa
|
|
|
|
BASE
|
|
Show details
|
|
5 |
The BDNF Val66Met Polymorphism Influences Reading Ability and Patterns of Neural Activation in Children
|
|
|
|
BASE
|
|
Show details
|
|
6 |
Shedding New Light on Reading in Spanish-English and French-English Bilingual School Children: an fNIRS Investigation ...
|
|
|
|
BASE
|
|
Show details
|
|
7 |
Does early exposure to a visual signed language “hurt” auditory language tissue development: Evidence from fNIRS neuroimaging of language processing in deaf individuals with cochlear implants! ...
|
|
|
|
BASE
|
|
Show details
|
|
8 |
The BDNF Val66Met Polymorphism Influences Reading Ability and Patterns of Neural Activation in Children.
|
|
|
|
BASE
|
|
Show details
|
|
|
|