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Multimodal Neural and Behavioral Data Predict Response to Rehabilitation in Chronic Poststroke Aphasia
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In: Stroke (2022)
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| 2 |
Factors affecting outcomes for semantic feature analysis treatment in post-stroke bilingual aphasia
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Behavioral and neural effects of intensive cognitive and communication rehabilitation in young college-bound adults with acquired brain injury
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Varying degrees of cognitive control and its impact on lexical access during verbal fluency tasks in bilingual persons with aphasia
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Acquired Brain Injury in Adults: A Review of Pathophysiology, Recovery, and Rehabilitation
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In: Perspect ASHA Spec Interest Groups (2021)
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Clustering and Switching in Verbal Fluency Across Varying Degrees of Cognitive Control Demands: Evidence From Healthy Bilinguals and Bilingual Patients With Aphasia
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In: Neurobiol Lang (Camb) (2021)
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| 7 |
Predicting language treatment response in bilingual aphasia using neural network-based patient models
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In: Sci Rep (2021)
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| 8 |
Telerehabilitation for Word Retrieval Deficits in Bilinguals With Aphasia: Effectiveness and Reliability as Compared to In-person Language Therapy
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In: Front Neurol (2021)
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| 9 |
Predicting language recovery in post-stroke aphasia using behavior and functional MRI
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In: Sci Rep (2021)
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| 10 |
Telerehabilitation for word retrieval deficits in bilinguals with aphasia: Effectiveness and reliability as compared to in-person language therapy
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| 11 |
A Virtual, Randomized, Control Trial of a Digital Therapeutic for Speech, Language, and Cognitive Intervention in Post-stroke Persons With Aphasia ; Frontiers in Neurology
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| 12 |
Aphasia management in growing multiethnic populations
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In: Research outputs 2014 to 2021 (2020)
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| 13 |
Epilogue: Harnessing the experimental and clinical resources to address service imperatives in multiethnic aphasia caseloads
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In: Research outputs 2014 to 2021 (2020)
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| 14 |
Predicting treatment outcomes for bilinguals with aphasia using computational modeling: Study protocol for the PROCoM randomised controlled trial
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Abstract:
Introduction Bilinguals with aphasia (BWA) present varying degrees of lexical access impairment and recovery across their two languages. Because both languages may benefit from therapy, identifying the optimal target language for treatment is a current challenge for research and clinical practice. Prior research has demonstrated that the BiLex computational model can accurately simulate lexical access in healthy bilinguals, and language impairment and treatment response in bilingual aphasia. Here, we aim to determine whether BiLex can predict treatment outcomes in BWA in the treated and the untreated language and compare these outcome predictions to determine the optimal language for rehabilitation. Methods and analysis The study involves a prospective parallel-group, double-blind, randomised controlled trial. Forty-eight Spanish–English BWA will receive 20 sessions of semantic treatment for lexical retrieval deficits in one of their languages and will complete assessments in both languages prior and after treatment. Participants will be randomly assigned to an experimental group receiving treatment in the optimal language determined by the model or a control group receiving treatment in the language opposite to the model’s recommendation. Primary treatment outcomes include naming probes while secondary treatment outcomes include tests tapping additional language domains. Treatment outcomes will be compared across the two groups using 2×2 mixed effect models for repeated measures Analysis of variance (ANOVA) on metrics of treatment effects commonly employed in rehabilitation studies (ie, effect size and percentage change). Ethics and dissemination All procedures included in this protocol (protocol number 29, issue date: 19 March 2019) were approved by the Boston University Charles River Campus Institutional Review Board at Boston, Massachusetts (reference number: 4492E). The results of this study will be published in peer-reviewed scientific journals and will be presented at national and international conferences. Trial registration number NCT02916524 .
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Keyword:
Rehabilitation medicine
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URL: http://bmjopen.bmj.com/cgi/content/short/10/11/e040495
https://doi.org/10.1136/bmjopen-2020-040495
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| 15 |
Videoconference Administration of the Western Aphasia Battery–Revised: Feasibility and Validity
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In: Am J Speech Lang Pathol (2020)
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| 16 |
Predicting treatment outcomes for bilinguals with aphasia using computational modeling: Study protocol for the PROCoM randomised controlled trial
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In: BMJ Open (2020)
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| 17 |
Verbal fluency as a measure of lexical access and cognitive control in bilingual persons with aphasia
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In: Aphasiology (2020)
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| 18 |
Functional Near-Infrared Spectroscopy in the Study of Speech and Language Impairment Across the Life Span: A Systematic Review
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In: Am J Speech Lang Pathol (2020)
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| 19 |
Pre-treatment graph measures of a functional semantic network are associated with naming therapy outcomes in chronic aphasia
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In: Brain Lang (2020)
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