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41
Glioblastoma Stem Cells
In: Journal of Health Disparities Research and Practice (2016)
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42
Unhealthy Eating Habits in the Marshall Islands Result from Deteriorating Reef Systems
In: Journal of Health Disparities Research and Practice (2016)
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43
3-Dimensional Scanning to Determine Body Volume and Composition With and Without a Wetsuit
In: Journal of Health Disparities Research and Practice (2016)
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44
Pilot Study: Placental Weight Ratio in Diabetic Women with Preeclampsia
In: Journal of Health Disparities Research and Practice (2016)
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45
An Intervention to Promote Navajo Gardening, Nutrition, and Community Wellness
In: Journal of Health Disparities Research and Practice (2016)
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46
HIV-1 Vpr Causes Synaptodendritic Damage in Neurons
In: Journal of Health Disparities Research and Practice (2016)
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47
Pyruvate Kinase type M2 (PKM2) Promotes Cancer Cell Metastasis Through Interacting with TWIST-1
In: Journal of Health Disparities Research and Practice (2016)
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48
Overground vs. Treadmill Running: Do Runners Use the Same Strategy to Adjust Stride Length and Frequency While Running at Different Velocities?
In: Journal of Health Disparities Research and Practice (2016)
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49
Mapping Snail Spatial Distribution in Guam’s Rivers
In: Journal of Health Disparities Research and Practice (2016)
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50
Exploration of Antagonist Efficacy for LPrA2 Like Peptide
In: Journal of Health Disparities Research and Practice (2016)
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51
Polymorphisms in Alcohol Dehydrogenase (ADH): A case study on the effects of ADH and ALDH on alcoholism among Native American population
In: Journal of Health Disparities Research and Practice (2016)
Abstract: Genetic variations in an individual affects the way alcohol is metabolized in the body. Alcohol Dehydrogenase (ADH) and Aldehyde Dehydrogenase (ALDH) are the two known enzymes that participate in alcohol metabolism. Polymorphisms of these enzymes are reported to make one more or less susceptible to alcoholism in some ethnic groups. The current study is a review of various articles highlighting the effects of ADH and ALDH on different populations. A study of 26 Native American, 21 Inuit, and 17 caucasian ethnic groups revealed the influence of ADH and ALDH on alcohol dependence. In one of the studies, different ADH allele populations were studied and found that the presence of ADH1B*1 allele led to increase in alcoholism whereas ADH1B*2 and ADH1B*3 alleles led to decrease in alcoholism. In another study, each participant was given alcohol intravenously until their blood alcohol was at approximately 125 mg.%. The rate of metabolism was calculated using body weight, concentration of alcohol, and the time it took for blood alcohol levels to reach a desired amount. The rate of decline of alcohol metabolism among Caucasian was 0.370 mg.% per minute, Native American 0.259 mg.% per minute, and the Inuit population 0.264 mg.% per minute. The study found that the Native American and Inuit rate of decline were similar, and the alcohol metabolism is much slower than the Caucasian counterparts. ADH polymorphism affects the ability to metabolize alcohol at different rates among different ethnicities.
Keyword: Alcohol Metabolism; Alcoholism; and Multicultural Education; Bilingual; Community College Leadership; Higher Education; Immune System Diseases; Medicine and Health Sciences; Multilingual; Native American; Polymorphism; Public Health; Translational Medical Research; Virus Diseases
URL: https://digitalscholarship.unlv.edu/jhdrp/vol9/iss5/87
https://digitalscholarship.unlv.edu/cgi/viewcontent.cgi?article=1619&context=jhdrp
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52
Dietary Restriction in Drosophila melanogaster Increases Flight Duration
In: Journal of Health Disparities Research and Practice (2016)
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53
Distribution of Crown of Thorns (Acanthaster planci) Outbreaks along the North Shore of TutuilaDistribution of Crown of Thorns (Acanthaster planci) Outbreaks along the North Shore of Tutuila
In: Journal of Health Disparities Research and Practice (2016)
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54
Comparison of Three Mosquito Traps for Lymphatic Filariasis Molecular Xenomonitoring in American Samoa Villages
In: Journal of Health Disparities Research and Practice (2016)
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55
The Association between Food Insecurity, Glycemic Control, Self-Care, and Quality of Life in Adults with Type 2 Diabetes
In: Journal of Health Disparities Research and Practice (2016)
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56
Effects of Light Attenuation on Local and Bulk Mechanical Properties of Photopolymerized PEG Hydrogels
In: Journal of Health Disparities Research and Practice (2016)
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57
Prescription Drug Costs: Does Neighborhood Matter?
In: Journal of Health Disparities Research and Practice (2016)
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58
Banded Application of GeoJute® Barriers to a Representative Area in Guam’s Pago Watershed
In: Journal of Health Disparities Research and Practice (2016)
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59
Effects of Acculturation on Quality of Life, Chronic Diseases and Health Behaviors in Persons of African Ancestry
In: Journal of Health Disparities Research and Practice (2016)
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60
Wellness from Diabetes: Community Health and Diabetes Assessment
In: Journal of Health Disparities Research and Practice (2016)
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