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What's "up"? Impaired Spatial Preposition Processing in Posterior Cortical Atrophy.
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Play-based interventions to support social and communication development in autistic children aged 2–8 years: A scoping review ...
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Структура когнитивных нарушений при депрессивных расстройствах и принципы их терапии ... : Structure of Cognitive Impairments in Depressive Disorders and Principles of their Therapy ...
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What's "up"? Impaired Spatial Preposition Processing in Posterior Cortical Atrophy. ...
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Influence of TTS Systems Performance on Reaction Times in People with Aphasia
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In: Applied Sciences; Volume 11; Issue 23; Pages: 11320 (2021)
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Capacity of the CCC-2 to Discriminate ASD from Other Neurodevelopmental Disorders
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Play-based interventions to support social and communication development in autistic children aged 2–8 years: A scoping review
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Prostate-Specimen Antigen (PSA) Screening and Shared Decision Making Among Deaf and Hearing Male Patients.
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In: Journal of cancer education : the official journal of the American Association for Cancer Education, vol 35, iss 1 (2020)
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The Relationship between Expressive Language Sampling and Clinical Measures in Fragile X Syndrome and Typical Development.
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In: Brain sciences, vol 10, iss 2 (2020)
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Waiting for speech-language pathology services: a randomised controlled trial comparing therapy, advice and device
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The effect of a coding strategy that removes temporally masked pulses on speech perception by cochlear implant users. ...
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The Relationship between Expressive Language Sampling and Clinical Measures in Fragile X Syndrome and Typical Development
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In: Brain Sciences ; Volume 10 ; Issue 2 (2020)
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Специфика обследования и коррекции речевых нарушений у пациентки с подкорковой афазией ... : Examination and rehabilitation of speech disorders in a patient with subcortical aphasia ...
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Comprehension of the Presupposition Trigger Ye "Also" by Mandarin-Speaking Preschoolers With and Without Autism Spectrum Disorders
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In: Frontiers in Psychology ; 11 (2020). - 570453. - Frontiers Research Foundation. - eISSN 1664-1078 (2020)
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The effect of a coding strategy that removes temporally masked pulses on speech perception by cochlear implant users.
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Neuro-Clinical Signatures of Language Impairments after Acute Stroke: A VBQ Analysis of Quantitative Native CT Scans.
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Muller, S.; Dauyey, K.; Ruef, A.; Lorio, S.; Eskandari, A.; Schneider, L.; Beaud, V.; Roggenhofer, E.; Draganski, B.; Michel, P.; Kherif, F.
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In: Current topics in medicinal chemistry, vol. 20, no. 9, pp. 792-799 (2020)
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Abstract:
Ischemic stroke affects language production and/or comprehension and leads to devastating long-term consequences for patients and their families. Previous studies have shown that neuroimaging can increase our knowledge of the basic mechanisms of language recovery. Currently, models for predicting patients' outcomes have limited use in the clinic for the evaluation and optimization of rehabilitative strategies mostly because that are often based on high-resolution magnetic resonance imaging (MRI) data, which are not always possible to carry out in the clinical routine. Here, we investigate the use of Voxel-Based Morphometry (VBM), multivariate modelling and native Computed Tomography (nCT) scans routinely acquired in the acute stage of stroke for identifying biological signatures that explicate the relationships between brain anatomy and types of impairments. 80 stroke patients and 30 controls were included. nCT-scans were acquired in the acute ischemia stage and bedside clinical assessment from board-certified neurologist based on the NIH stroke scale. We use a multivariate Principal Component Analyses (PCA) to identify the brain signatures group the patients according to the presence or absence of impairment and identify the association between local Grey Matter (GM) and White Matter (WM) nCT values with the presence or absence of the impairment. Individual patient's nCT scans were compared to a group of controls' with no radiological signs of stroke to provide an automated delineation of the lesion. Consistently across the whole group the regions that presented significant difference GM and WM values overlap with known areas that support language processing. In summary, the method applied to nCT scans performed in the acute stage of stroke provided robust and accurate information about brain lesions' location and size, as well as quantitative values. We found that nCT and VBQ analyses are effective for identifying neural signatures of concomitant language impairments at the individual level, and neuroanatomical maps of aphasia at the population level. The signatures explicate the neurophysiological mechanisms underlying aetiology of the stroke. Ultimately, similar analyses with larger cohorts could lead to a more integrated multimodal model of behaviour and brain anatomy in the early stage of ischemic stroke.
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Keyword:
Brain biological signature stroke recovery; CT scans; Function-to-structure Mapping; Functional neuroimaging; ischemic stroke; language impairments; magnetic resonance imaging; Neuro-Clinical signatures; Stroke; Theoretical framework; VBQ analysis
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URL: https://serval.unil.ch/notice/serval:BIB_5CC695A3DED4
https://doi.org/10.2174/1568026620666200211113824
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Testing the therapeutic effects of transcranial direct current stimulation (tDCS) in semantic dementia: a double blind, sham controlled, randomized clinical trial
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In: ISSN: 1745-6215 ; Trials ; https://hal.sorbonne-universite.fr/hal-02407657 ; Trials, BioMed Central, 2019, 20 (1), pp.632. ⟨10.1186/s13063-019-3613-z⟩ (2019)
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Comprehension of conventional gestures in typical children, children with autism spectrum disorders and children with language disorders
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In: ISSN: 0222-9617 ; Neuropsychiatrie de l'Enfance et de l'Adolescence ; https://hal.sorbonne-universite.fr/hal-03179130 ; Neuropsychiatrie de l'Enfance et de l'Adolescence, Elsevier Masson, 2019, 67 (1), pp.1-9. ⟨10.1016/j.neurenf.2018.03.002⟩ (2019)
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Promotion of Healthy Humor Cancer Education Messages for the Deaf Community.
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In: Journal of cancer education : the official journal of the American Association for Cancer Education, vol 34, iss 2 (2019)
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Genetic testing and eHealth usage among Deaf women.
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In: Journal of genetic counseling, vol 28, iss 5 (2019)
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