• Refine your search:
  • 
    Keyword:
    
    • Genètica de poblacions humanes -- Àfrica del Nord (1)
  • 
    Creator / Publisher:
    
    • Bertranpetit, Jaume, 1952- (1)
    • Comas, David, 1969- (1)
    • Dobón Berenguer, Begoña, 1987- (1)
    • Hassan, Hisham Y. (1)
    • Laayouni, Hafid, 1968- (1)
    • Luisi, Pierre, 1985- (1)
    • Netea, Mihai G (1)
    • Ricaño Ponce, Isis (1)
    • Tahir, Hanan (1)
    • Wijmenga, Cisca (1)
    •   more
  • 
    Year
  • 
    Medium:
    
    • Online (1)
  • 
    Type:
    
    • Article (1)
  • 
    BLLDB-Access

Search in the Catalogues and Directories

All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Hits 1 – 1 of 1 1 The genetics of East African populations: a Nilo-Saharan component in the African genetic landscape Dobón Berenguer, Begoña, 1987-; Hassan, Hisham Y.; Laayouni, Hafid, 1968-; Luisi, Pierre, 1985-; Ricaño Ponce, Isis; Zhernakova, Alexandra; Wijmenga, Cisca; Tahir, Hanan; Comas, David, 1969-; Netea, Mihai G; Bertranpetit, Jaume, 1952-. - : Nature Publishing Group Abstract: East Africa is a strategic region to study human genetic diversity due to the presence of ethnically, linguistically, and geographically diverse populations. Here, we provide new insight into the genetic history of populations living in the Sudanese region of East Africa by analysing nine ethnic groups belonging to three African linguistic families: Niger-Kordofanian, Nilo-Saharan and Afro-Asiatic. A total of 500 individuals were genotyped for 200,000 single-nucleotide polymorphisms. Principal component analysis, clustering analysis using ADMIXTURE, FST statistics, and the three-population test were used to investigate the underlying genetic structure and ancestry of the different ethno-linguistic groups. Our analyses revealed a genetic component for Sudanese Nilo-Saharan speaking groups (Darfurians and part of Nuba populations) related to Nilotes of South Sudan, but not to other Sudanese populations or other sub-Saharan populations. Populations inhabiting the North of the region showed close genetic affinities with North Africa, with a component that could be remnant of North Africans before the migrations of Arabs from Arabia. In addition, we found very low genetic distances between populations in genes important for anti-malarial and anti-bacterial host defence, suggesting similar selective pressures on these genes and stressing the importance of considering functional pathways to understand the evolutionary history of populations. ; M.G.N. was supported by a Vici Grant of the Netherlands Organization for Scientific Research, and an ERC Consolidator Grant (nr. 310372). J.B. was supported by grant BFU2013-43726-P awarded by Ministerio de Economía y Competitividad (Spain) and with the support of Secretaria d’Universitats i Recerca del Departament d’Economia i Coneixement de la Generalitat de Catalunya (GRC 2014 SGR 866). B.D. is supported by F.P.U. grant FPU13/06813 from the Ministerio de Educación, Cultura y Deporte (Spain). C.W. is supported by the European Research Council under the European Union’s Seventh Frame-work Programme (FP/2007-2013)/ERC Grant Agreement [n. 2012-322698]. A.Z. holds a Rosalind Franklin fellowship from the University of Groningen. We thank the National Institute of Bioinformatics (http://www.inab.org) for computational support. Keyword: Genètica de poblacions humanes -- Àfrica del Nord URL: https://doi.org/10.1038/srep09996 http://hdl.handle.net/10230/25768 BASE Hide details

Mobile view All Catalogues UB Frankfurt Linguistik 0 IDS Mannheim 0 OLC Linguistik 0 UB Frankfurt Retrokatalog 0 DNB Subject Category Language 0 Institut für Empirische Sprachwissenschaft 0 Leibniz-Centre General Linguistics (ZAS) 0 Bibliographies BLLDB 0 BDSL 0 IDS Bibliografie zur deutschen Grammatik 0 IDS Bibliografie zur Gesprächsforschung 0 IDS Konnektoren im Deutschen 0 IDS Präpositionen im Deutschen 0 IDS OBELEX meta 0 MPI-SHH Linguistics Collection 0 MPI for Psycholinguistics 0 Linked Open Data catalogues Annohub 0 Online resources Link directory 0 Journal directory 0 Database directory 0 Dictionary directory 0 Open access documents BASE 1 Linguistik-Repository 0 IDS Publikationsserver 0 Online dissertations 0 Language Description Heritage 0