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All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Hits 1 – 19 of 19 1 Genetic Structure of IQ, Phonemic Decoding Skill, and Academic Achievement Lazaroo, Nikita K.; Bates, Timothy C.; Hansell, Narelle K.. - : Frontiers Media S.A., 2019 BASE Show details 2 Genetic structure of IQ, phonemic decoding skill, and academic achievement Lazaroo, Nikita K.; Bates, Timothy C.; Hansell, Narelle K.. - : Frontiers Research Foundation, 2019 BASE Show details 3 Genome-wide screening for DNA variants associated with reading and language traits Gialluisi, Alessandro; Newbury, Dianne F; Wilcutt, Erik G. - 2015 BASE Show details 4 Genetic variance in a component of the language acquisition device: ROBO1 polymorphisms associated with phonological buffer deficits Bates, Timothy C.; Luciano, Michelle; Medland, Sarah E.; Montgomery, Grant W.; Wright, Margaret J.; Martin, Nicholas G.. - : Springer, 2011 Abstract: The region containing ROBO1 (Chromosome 3p12.3) has been implicated as a susceptibility gene for reading disorder and language deficit by translocation and linkage data. No association studies have yet been reported supporting any candidate gene. Here we report the first association of this gene with language deficits, specifically with phonological buffer deficits (a phenotype implicated in language acquisition, Specific Language Impairment and Speech Sound Disorder) and dyslexia (reading and spelling ability traits) in an unselected sample of adolescent twins and their siblings. Family-based analyses were performed on 144 tag SNPs in ROBO1, typed in 538 families with up to five offspring and tested for association with a developmental marker of language impairment (phonological buffer capacity, assessed using non word repetition).A reading and spelling ability measure-based on validated measures of lexical processing (irregular word) and grapheme-phoneme decoding (pseudo word)-and measures of short-term and working memory were also analysed. Significant association for phonological buffer capacity was observed for 21 of 144 SNPs tested, peaking at 8.70 x 10(-05) and 9.30 x 10(-05) for SNPs rs6803202 and rs4535189 respectively for nonword repetition, values that survive correction for multiple testing. Twenty-two SNPs showed significant associations for verbal storage (forward digit span)-a trait linked to phonological span. By contrast, just 5 SNPs reached nominal significance for working-memory, not surviving correction, and, importantly, only one SNP in the 144 tested reached nominal significance (0.04) for association with reading and spelling ability. These results provide strong support for ROBO1 as a gene involved in a core trait underpinning language acquisition, with a specific function in supporting a short-term buffer for arbitrary phonological strings. These effects of ROBO1 appear to be unrelated to brain mechanisms underpinning reading ability, at least by adolescence. While replication will be critical, the present results strongly support ROBO1 as the first gene discovered to be associated with language deficits affecting normal variation in language ability. Its functional role in neuronal migration underlying bilateral symmetry and lateralization of neuronal function further suggests a role in the evolution of human language ability. Keyword: 1105 Ecology; 1311 Genetics; 2716 Genetics (clinical); Association; Behavior and Systematics; Dyslexia; Evolution; Family-based; Language; Reading ability; ROBO1; Specific language impairment; Spelling ability URL: https://espace.library.uq.edu.au/view/UQ:612048 BASE Hide details 5 Dyslexia and DCDC2: normal variation in reading and spelling is associated with DCDC2 polymorphisms in an Australian population sample Lind, Penelope A; Luciano, Michelle; Wright, Margaret J. - : Nature Publishing Group, 2010 BASE Show details 6 Dyslexia and DCDC2: Normal variation in reading and spelling is associated with DCDC2 polymorphisms in an Australian population sample Lind, Penelope A.; Luciano, Michelle; Wright, Margaret J.. - : Nature Publishing Group, 2010 BASE Show details 7 Genes for a component of the language acquisition mechanism: ROBO1 polymorphisms associated with phonological buffer deficits Bates, Timothy C.; Luciano, Michelle; Montgomery, Grant W.. - : Springer New York LLC, 2010 BASE Show details 8 Genetic covariation between the author recognition test and reading and verbal abilities: What can we learn from the analysis of high performance? Martin, Nicolas W.; Hansell, Narelle K.; Wainwright, Mark A.. - : Springer New York, 2009 BASE Show details 9 Genetic and environmental bases of reading and spelling : a unified genetic dual route model Luciano, Michelle; Martin, Nicholas G.; Castles, Anne... In: Reading and writing. - New York, NY : Springer Science+Business Media 20 (2007) 1-2, 147-171 BLLDB OLC Linguistik Show details 10 Genetic and environmental bases of reading and spelling : a unified genetic dual route model Bates, Timothy C; Castles, Anne; Luciano, Michelle. - : Springer Netherlands, 2007 BASE Show details 11 The ongoing adaptive evolution of ASPM and microcephalin is not explained by increased intelligence Mekel-Bobrov, Nitzan; Posthuma, Danielle; Gilbert, Sandra L.. - : Oxford University Press, 2007 BASE Show details 12 Genetic and environmental bases of reading and spelling: a unified genetic dual route model Bates, Timothy C.; Castles, Anne; Luciano, Michelle. - : Springer Netherlands, 2007 BASE Show details 13 Genetic architecture of language: Phonological and lexical storage capacity deficits in specific language impairment & dyslexia Bates, Timothy C.; Luciano, Michelle; Wright, Margaret J.. - : SPRINGER, 2007 BASE Show details 14 John Marshall and the developmental dyslexias Coltheart, Max; Bates, Timothy C.; Castles, Anne In: Aphasiology. - London [u.a.] : Routledge, Taylor & Francis Group 20 (2006) 9-11, 871-892 BLLDB OLC Linguistik Show details 15 John Marshall and the developmental dyslexias Castles, Anne; Bates, Timothy C; Coltheart, Max. - : Psychology Press, 2006 BASE Show details 16 The effects of local and global processing demands on perception and action Hughes, Laura E.; Bates, Timothy C.; Davies, Anne M.Aimola In: Brain and cognition. - San Diego, Calif. [u.a.] : Elsevier Science 59 (2005) 1, 71-81 OLC Linguistik Show details 17 Behaviour genetic analyses of reading and spelling: a component processes approach Bates, Timothy C.; Castles, Anne; Coltheart, Max. - : John Wiley & Sons, 2004 BASE Show details 18 Crystallized intelligence as a product of speed and drive for experience : the relationship of inspection time and openness to g and Gc Bates, Timothy C; Shieles, Alexandra. - : Elsevier, 2003 BASE Show details 19 Intelligence arguments and Australian psychology: a reply to Stankov and an alternative view Bates, Timothy, C.; Stough, Con In: Australian Psychologist, Vol. 35, no. 1 (Mar 2000), pp. 68-72 (2000) BASE Show details

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