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Mapping of Language-and-Memory Networks in Patients With Temporal Lobe Epilepsy by Using the GE2REC Protocol
In: ISSN: 1662-5161 ; Frontiers in Human Neuroscience ; https://hal-cnrs.archives-ouvertes.fr/hal-03529823 ; Frontiers in Human Neuroscience, Frontiers, 2022, 15, ⟨10.3389/fnhum.2021.752138⟩ (2022)
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Mapping of Language-and-Memory Networks in Patients With Temporal Lobe Epilepsy by Using the GE2REC Protocol
In: Front Hum Neurosci (2022)
Abstract: Preoperative mapping of language and declarative memory functions in temporal lobe epilepsy (TLE) patients is essential since they frequently encounter deterioration of these functions and show variable degrees of cerebral reorganization. Due to growing evidence on language and declarative memory interdependence at a neural and neuropsychological level, we propose the GE2REC protocol for interactive language-and-memory network (LMN) mapping. GE2REC consists of three inter-related tasks, sentence generation with implicit encoding (GE) and two recollection (2REC) memory tasks: recognition and recall. This protocol has previously been validated in healthy participants, and in this study, we showed that it also maps the LMN in the left TLE (N = 18). Compared to healthy controls (N = 19), left TLE (LTLE) showed widespread inter- and intra-hemispheric reorganization of the LMN through reduced activity of regions engaged in the integration and the coordination of this meta-network. We also illustrated how this protocol could be implemented in clinical practice individually by presenting two case studies of LTLE patients who underwent efficient surgery and became seizure-free but showed different cognitive outcomes. This protocol can be advantageous for clinical practice because it (a) is short and easy to perform; (b) allows brain mapping of essential cognitive functions, even at an individual level; (c) engages language-and-memory interaction allowing to evaluate the integrative processes within the LMN; (d) provides a more comprehensive assessment by including both verbal and visual modalities, as well as various language and memory processes. Based on the available postsurgical data, we presented preliminary results obtained with this protocol in LTLE patients that could potentially inform the clinical practice. This implies the necessity to further validate the potential of GE2REC for neurosurgical planning, along with two directions, guiding resection and describing LMN neuroplasticity at an individual level.
Keyword: Neuroscience
URL: https://doi.org/10.3389/fnhum.2021.752138
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772037/
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Reconfiguration dynamics of a language-and-memory network in healthy participants and patients with temporal lobe epilepsy
In: ISSN: 2213-1582 ; Neuroimage-Clinical ; https://hal.univ-grenoble-alpes.fr/hal-03247903 ; Neuroimage-Clinical, Elsevier, 2021, 31, pp.102702. ⟨10.1016/j.nicl.2021.102702⟩ (2021)
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4
Interactive mapping of language and memory with the GE2REC protocol
In: ISSN: 1931-7557 ; EISSN: 1931-7565 ; Brain imaging and behavior (Brain Imaging Behav) ; https://hal.univ-grenoble-alpes.fr/hal-03091631 ; Brain imaging and behavior (Brain Imaging Behav), Secaucus, NJ : Springer, In press, ⟨10.1007/s11682-020-00355-x⟩ (2021)
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5
Reconfiguration dynamics of a language-and-memory network in healthy participants and patients with temporal lobe epilepsy
In: Neuroimage Clin (2021)
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6
Interactive mapping of language and memory with the GE2REC protocol
In: Brain Imaging Behav (2020)
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7
GE2REC protocol for interactive mapping of language and memory processes in temporal lobe epilepsy
In: Society for the Neurobiology of Language Annual Meeting (SNL) ; https://hal.univ-grenoble-alpes.fr/hal-03247992 ; Society for the Neurobiology of Language Annual Meeting (SNL), Aug 2019, Helsinki, Finland (2019)
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8
The ConDialInt Model: Condensation, Dialogality, and Intentionality Dimensions of Inner Speech Within a Hierarchical Predictive Control Framework
In: EISSN: 1664-1078 ; Frontiers in Psychology ; https://hal.archives-ouvertes.fr/hal-02290943 ; Frontiers in Psychology, Frontiers, 2019, Exploring the Nature, Content, and Frequency of Intrapersonal Communication, 10, pp.2019. ⟨10.3389/fpsyg.2019.02019⟩ ; https://www.frontiersin.org/article/10.3389/fpsyg.2019.02019 (2019)
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9
Neural correlates of inner speaking, imitating and hearing: an fMRI study
In: ICPhS 2019 - 19th International Congress of Phonetic Sciences ; https://hal.archives-ouvertes.fr/hal-02367806 ; ICPhS 2019 - 19th International Congress of Phonetic Sciences, Aug 2019, Melbourne, Australia ; https://www.icphs2019.org (2019)
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10
The ConDialInt Model: Condensation, Dialogality, and Intentionality Dimensions of Inner Speech Within a Hierarchical Predictive Control Framework
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11
Aging Modulates the Hemispheric Specialization during Word Production
Hoyau, Elena; Boudiaf, Naila; Cousin, Emilie. - : Frontiers Media S.A., 2017
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12
NEREC, an effective brain mapping protocol for combined language and long-term memory functions
In: ISSN: 1525-5050 ; EISSN: 1525-5069 ; Epilepsy & Behavior ; https://hal.archives-ouvertes.fr/hal-01413830 ; Epilepsy & Behavior, [San Diego CA]: Elsevier B.V., 2015, 53, pp.140 - 148. ⟨10.1016/j.yebeh.2015.09.017⟩ (2015)
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13
Hemispheric specialization for language according to grapho-phonemic transformation and gender: a divided visual field experiment
In: Brain and cognition. - San Diego, Calif. [u.a.] : Elsevier Science 69 (2009) 3, 465-471
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14
Hemispheric specialization for language according to grapho-phonemic transformation and gender. A divided visual field experiment
In: Brain and cognition. - San Diego, Calif. [u.a.] : Elsevier Science 69 (2009) 3, 465-471
OLC Linguistik
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15
Some aspects of language plasticity in epileptic patients as assessed by functional MRI
In: Some Aspects of Speech and the Brain (Frankfurt am Main, 2009), p. 91-114
MPI für Psycholinguistik
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16
Hemispheric specialization for language according to grapho-phonemic transformation and gender. A divided visual field experiment.
In: ISSN: 0278-2626 ; EISSN: 1090-2147 ; Brain and Cognition ; https://hal.archives-ouvertes.fr/hal-00967645 ; Brain and Cognition, Elsevier, 2009, 69 (3), pp.465-71. ⟨10.1016/j.bandc.2008.10.001⟩ (2009)
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Modulation de la spécialisation hémisphérique du langage par le degré de transparence grapho-phonémique et le sexe. Etude comportementale en champ visuel divisé
In: ISSN: 2101-6739 ; Revue de neuropsychologie, neurosciences cognitives et cliniques ; https://hal.archives-ouvertes.fr/hal-00862010 ; Revue de neuropsychologie, neurosciences cognitives et cliniques, John Libbey Eurotext, 2009, 4 (1), pp.288-98. ⟨10.1684/nrp.2009.0051⟩ (2009)
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18
Functional MRI approach for assessing hemispheric predominance of regions activated by a phonological and a semantic task.
In: ISSN: 0720-048X ; European Journal of Radiology ; https://hal.archives-ouvertes.fr/hal-00798632 ; European Journal of Radiology, Elsevier, 2007, pp.63(2):274-85 (2007)
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19
Functional MRI approach for assessing hemispheric predominance of regions activated by a phonological and a semantic task
In: ISSN: 0720-048X ; European Journal of Radiology ; https://hal.archives-ouvertes.fr/hal-00169574 ; European Journal of Radiology, Elsevier, 2007, 63, pp.274-285 (2007)
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20
Hemispheric predominance assessment of phonology and semantics : a divided visual field experiment
In: Brain and cognition. - San Diego, Calif. [u.a.] : Elsevier Science 61 (2006) 3, 298-304
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