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All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Page: 1 2 3 4 5...10 Hits 1 – 20 of 199 1 A 'Mini Linguistic State Examination' to classify primary progressive aphasia. ... Patel, Nikil; Peterson, Katie A; Ingram, Ruth U. - : Apollo - University of Cambridge Repository, 2022 BASE Show details 2 A 'Mini Linguistic State Examination' to classify primary progressive aphasia. ... Patel, Nikil; Peterson, Katie A; Ingram, Ruth U. - : Apollo - University of Cambridge Repository, 2022 BASE Show details 3 Language Disorder in Progressive Supranuclear Palsy and Corticobasal Syndrome: Neural Correlates and Detection by the MLSE Screening Tool. ... Peterson, Katie A; Jones, P Simon; Patel, Nikil. - : Apollo - University of Cambridge Repository, 2021 BASE Show details 4 Language Disorder in Progressive Supranuclear Palsy and Corticobasal Syndrome: Neural Correlates and Detection by the MLSE Screening Tool. ... Peterson, Katie; Jones, Simon; Patel, Nikil. - : Apollo - University of Cambridge Repository, 2021 BASE Show details 5 Predicting loss of independence and mortality in frontotemporal lobar degeneration syndromes. ... Murley, Alexander; Rouse, Matthew; Coyle-Gilchrist, Ian TS. - : Apollo - University of Cambridge Repository, 2021 BASE Show details 6 Language impairment in progressive supranuclear palsy and corticobasal syndrome. ... Peterson, Katie; Patterson, Karalyn; Rowe, James. - : Apollo - University of Cambridge Repository, 2021 BASE Show details 7 Language Disorder in Progressive Supranuclear Palsy and Corticobasal Syndrome: Neural Correlates and Detection by the MLSE Screening Tool ... Peterson, Katie A.; Jones, P. Simon; Patel, Nikil. - : Apollo - University of Cambridge Repository, 2021 BASE Show details 8 Language Disorder in Progressive Supranuclear Palsy and Corticobasal Syndrome: Neural Correlates and Detection by the MLSE Screening Tool Peterson, Katie A.; Jones, P. Simon; Patel, Nikil... In: Front Aging Neurosci (2021) BASE Show details 9 Language impairment in progressive supranuclear palsy and corticobasal syndrome. Peterson, Katie; Patterson, Karalyn; Rowe, James. - : Springer Science and Business Media LLC, 2021. : J Neurol, 2021 BASE Show details 10 Language impairment in progressive supranuclear palsy and corticobasal syndrome Peterson, Katie A.; Patterson, Karalyn; Rowe, James B.. - : Springer Berlin Heidelberg, 2021. : Journal of Neurology, 2021 BASE Show details 11 Language Disorder in Progressive Supranuclear Palsy and Corticobasal Syndrome: Neural Correlates and Detection by the MLSE Screening Tool Peterson, Katie A.; Jones, P. Simon; Patel, Nikil. - : Frontiers Media S.A., 2021. : Frontiers in Aging Neuroscience, 2021 BASE Show details 12 Language Disorder in Progressive Supranuclear Palsy and Corticobasal Syndrome: Neural Correlates and Detection by the MLSE Screening Tool. Peterson, Katie A; Jones, P Simon; Patel, Nikil; Tsvetanov, Kamen A; Ingram, Ruth; Cappa, Stefano F; Lambon Ralph, Matthew A; Patterson, Karalyn; Garrard, Peter; Rowe, James B In: essn: 1663-4365 ; nlmid: 101525824 (2021) Abstract: Background : Progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS) affect speech and language as well as motor functions. Clinical and neuropathological data indicate a close relationship between these two disorders and the non-fluent variant of primary progressive aphasia (nfvPPA). We use the recently developed Mini Linguistic State Examination tool (MLSE) to study speech and language disorders in patients with PSP, CBS, and nfvPPA, in combination with structural magnetic resonance imaging (MRI). Methods : Fifty-one patients (PSP N = 13, CBS N = 19, nfvPPA N = 19) and 30 age-matched controls completed the MLSE, the short form of the Boston Diagnostic Aphasia Examination (BDAE), and the Addenbrooke's Cognitive Examination III. Thirty-eight patients and all controls underwent structural MRI at 3 Tesla, with T1 and T2-weighted images processed by surface-based and subcortical segmentation within FreeSurfer 6.0.0 to extract cortical thickness and subcortical volumes. Morphometric differences were compared between groups and correlated with the severity of speech and language impairment. Results : CBS and PSP patients showed impaired MLSE performance, compared to controls, with a similar language profile to nfvPPA, albeit less severe. All patient groups showed reduced cortical thickness in bilateral frontal regions and striatal volume. PSP and nfvPPA patients also showed reduced superior temporal cortical thickness, with additional thalamic and amygdalo-hippocampal volume reductions in nfvPPA. Multivariate analysis of brain-wide cortical thickness and subcortical volumes with MLSE domain scores revealed associations between performance on multiple speech and language domains with atrophy of left-lateralised fronto-temporal cortex, amygdala, hippocampus, putamen, and caudate. Conclusions : The effect of PSP and CBS on speech and language overlaps with nfvPPA. These three disorders cause a common anatomical pattern of atrophy in the left frontotemporal language network and striatum. The MLSE is a short clinical screening tool that can identify the language disorder of PSP and CBS, facilitating clinical management and patient access to future clinical trials. Keyword: Aphasia; Corticobasal Syndrome; Language; Progressive Supranuclear Palsy; Speech URL: https://doi.org/10.17863/CAM.75354 https://www.repository.cam.ac.uk/handle/1810/327900 BASE Hide details 13 Language Disorder in Progressive Supranuclear Palsy and Corticobasal Syndrome: Neural Correlates and Detection by the MLSE Screening Tool. Peterson, Katie; Jones, Simon; Patel, Nikil. - : Frontiers Media SA, 2021. : Front Aging Neurosci, 2021 BASE Show details 14 Graded, multidimensional intra- and intergroup variations in primary progressive aphasia and post-stroke aphasia. Ingram, Ruth U; Halai, Ajay D; Pobric, Gorana... In: Brain : a journal of neurology, vol 143, iss 10 (2020) BASE Show details 15 Anterior temporal lobe is necessary for efficient lateralised processing of spoken word identity. ... Cope, Thomas; Shtyrov, Yury; MacGregor, Lucy. - : Apollo - University of Cambridge Repository, 2020 BASE Show details 16 Anterior temporal lobe is necessary for efficient lateralised processing of spoken word identity ... Cope, Thomas E.; Shtyrov, Yury; MacGregor, Lucy J.. - : Freie Universität Berlin, 2020 BASE Show details 17 Redefining the multidimensional clinical phenotypes of frontotemporal lobar degeneration syndromes ... Murley, Alexander; Coyle-Gilchrist, Ian; Rouse, Matthew. - : Apollo - University of Cambridge Repository, 2020 BASE Show details 18 Graded, multidimensional intra- and intergroup variations in primary progressive aphasia and post-stroke aphasia. ... Ingram, Ruth U; Halai, Ajay; Pobric, Gorana. - : Apollo - University of Cambridge Repository, 2020 BASE Show details 19 Predicting loss of independence and mortality in frontotemporal lobar degeneration syndromes ... Murley, Alexander; Rouse, Matthew; Coyle-Gilchrist, Ian. - : Apollo - University of Cambridge Repository, 2020 BASE Show details 20 Predicting loss of independence and mortality in frontotemporal lobar degeneration syndromes Murley, Alexander; Rouse, Matthew; Coyle-Gilchrist, Ian. - : Cold Spring Harbor Laboratory, 2020. : Journal of Neurology, Neurosurgery and Psychiatry, 2020 BASE Show details Page: 1 2 3 4 5...10

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