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Alcohol consumption and neurocognitive deficits in people with well-treated HIV in Switzerland. ...
Abstract: BACKGROUND Hazardous alcohol consumption and HIV infection increase the risk of neurocognitive impairment (NCI). We examined the association between alcohol consumption and specific neurocognitive domain function in people with HIV (PWH) taking modern antiretroviral therapy. METHODS The Neurocognitive Assessment in the Metabolic and Aging Cohort (NAMACO) study is a prospective, longitudinal, multicentre and multilingual (French, German and Italian) study of patients aged ≥45 years old enrolled in the Swiss HIV Cohort Study (SHCS). Baseline data from 981 study participants were examined. Five neurocognitive domains were evaluated: motor skills, speed of information processing, attention/working memory, executive function and verbal episodic memory. NCI was examined as binary (presence/absence) and continuous (mean z-score) outcomes against Alcohol Use Disorders Identification Test for Consumption (AUDIT-C) scores using logistic and linear regression models, respectively. RESULTS Most participants (96.2%) had ...
Keyword: 610 Medicine & health
URL: https://boris.unibe.ch/153477/
https://dx.doi.org/10.48350/153477
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Alcohol consumption and neurocognitive deficits in people with well-treated HIV in Switzerland
In: PLoS One (2021)
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