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Simple Search
Hits 1 – 14 of 14
1
Improving Cross-Lingual Reading Comprehension with Self-Training ...
Huang, Wei-Cheng
;
Huang, Chien-yu
;
Lee, Hung-yi
. - : arXiv, 2021
BASE
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2
Extreme Multi-label Learning for Semantic Matching in Product Search ...
Chang, Wei-Cheng
;
Jiang, Daniel
;
Yu, Hsiang-Fu
. - : arXiv, 2021
BASE
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3
Gene-level association results from applying gene- ε to mean corpuscular volume (MCV), assayed in European-ancestry individuals in the UK Biobank.
Wei Cheng
(52808);
Sohini Ramachandran
(36819);
Lorin Crawford
(4278949). - 2020
BASE
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4
Gene-level association results from applying gene- ε to body mass index (BMI), assayed in European-ancestry individuals in the UK Biobank.
Wei Cheng
(52808);
Sohini Ramachandran
(36819);
Lorin Crawford
(4278949). - 2020
BASE
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5
Gene-level association results from applying gene- ε to waist-hip ratio (WHR), assayed in European-ancestry individuals in the UK Biobank.
Wei Cheng
(52808);
Sohini Ramachandran
(36819);
Lorin Crawford
(4278949). - 2020
BASE
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6
Gene-level association results from applying gene- ε to body height (panels A and C) and mean platelet volume (MPV; panels B and D), assayed in European-ancestry individuals in the UK Biobank.
Wei Cheng
(52808);
Sohini Ramachandran
(36819);
Lorin Crawford
(4278949). - 2020
Abstract:
Body height has been estimated to have a narrow-sense heritability h 2 in the range of 0.45 to 0.80 [ 6 , 31 – 39 ]; while, MPV has been estimated to have h 2 between 0.50 and 0.70 [ 33 , 34 , 58 ]. Manhattan plots of gene- ε gene-level association P -values using Elastic Net regularized effect sizes for (A) body height and (B) MPV. The purple dashed line indicates a log-transformed Bonferroni-corrected significance threshold ( P = 3.49×10 −6 correcting for 14,322 autosomal genes analyzed). We color code all significant genes identified by gene- ε in orange, and annotate genes overlapping with the database of Genotypes and Phenotypes (dbGaP). In (C) and (D) , we conduct gene set enrichment analysis using Enrichr [ 46 , 59 ] to identify dbGaP categories enriched for significant gene-level associations reported by gene- ε . We highlight categories with Q -values (i.e., false discovery rates) less than 0.05 and annotate corresponding genes in the Manhattan plots in (A) and (B) , respectively. For height, the only significant dbGAP category is “Body Height”, with nine of the genes identified by gene- ε appearing in this category. For MPV, the two significant dbGAP categories are “Platelet Count” and “Face”—the first of which is directly connected to trait [ 57 , 60 , 61 ].
Keyword:
Biological Sciences not elsewhere classified
;
case-control studies
;
enrichment studies
;
European-ancestry individuals
;
gene
;
Genetics
;
genome-wide SNP-level
;
Mathematical Sciences not elsewhere classified
;
Medicine
;
model assumptions
;
non-null SNP effect size distributions
;
nonzero effects
;
polygenic traits
;
Recent efforts
;
small-to-intermediate SNP effects
;
summary statistics
;
UK Biobank
;
univariate genome-wide association studies
;
variant
URL:
https://doi.org/10.1371/journal.pgen.1008855.g004
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7
Gene-level association results from applying gene- ε to platelet count (PLC), assayed in European-ancestry individuals in the UK Biobank.
Wei Cheng
(52808);
Sohini Ramachandran
(36819);
Lorin Crawford
(4278949). - 2020
BASE
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8
Crown morphology of the mandibular first molars with distolingual roots
Lee, Wei-Cheng
;
Ni, Chih-Wei
;
Lin, Fu-Gong
. - : Association for Dental Sciences of the Republic of China, 2016
BASE
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9
Policy sharing between multiple mobile robots using decision trees
Chen, Yu-Jen
;
Hwang, Kao-Shing
;
Jiang, Wei-Cheng
In:
Information sciences. - New York, NY : Elsevier Science Inc.
234 (2013), 112-120
OLC Linguistik
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10
Seeing beauty in a face: a framework for poetry translation & its criticism
Lin, Wei-Cheng
. - 2007
BASE
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11
Logische Notwendigkeit und grammatische Regeln : zur Klärung ihres Verhältnisses ohne Konventionalismus oder linguistische Theorie der notwendigen Wahrheit
Kung, Wei-cheng
. - Frankfurt am Main [u.a.] : Lang, 2000
BLLDB
UB Frankfurt Linguistik
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12
Some ethnic gays are coming home; Or, the trouble with interraciality
Chu, Wei-cheng Raymond
In:
Textual practice. - London : Routledge
11 (1997) 2, 219-236
OLC Linguistik
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13
Identification of Code-Switched Sentences and Words Using Language Modeling Approaches
Liang-Chih Yu
;
Wei-Cheng He
;
Wei-Nan Chien
...
In: http://downloads.hindawi.com/journals/mpe/2013/898714.pdf
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14
A Language Modeling Approach to Identifying Code-Switched Sentences and Words
Liang-chih Yu
;
Wei-cheng He
;
Wei-nan Chien
In: http://www.aclweb.org/anthology/W/W12/W12-6303.pdf
BASE
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