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Ready. Speak. Action. Action word production difficulties in Parkinson's disease ...
Oosterhuis, Elise. - : Open Science Framework, 2022
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2
Uma revisão scoping : a influência da reserva cognitiva na proteção do estado cognitivo pós-lesão cerebral adquirida
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3
Education differentially contributes to cognitive reserve across racial/ethnic groups
Avila, Justina F.; Rentería, Miguel Arce; Jones, Richard N.. - : Wiley Periodicals, Inc., 2021. : Minnesota Population Center, 2021
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Bilingualism's Effects on Resting-State Functional Connectivity in Mild Cognitive Impairment
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Bilingualism as a Proxy of Cognitive Reserve
Abstract: Previous studies have reported bilingualism to be a proxy of cognitive reserve (CR) based on evidence that bilinguals express dementia symptoms ~4 years later than monolinguals yet present with greater neuropathology at time of diagnosis when clinical levels are similar. This dissertation presents two studies that provide further evidence for the contribution of bilingualism to CR. The first study uses a novel brain health matching paradigm. Forty cognitively normal bilinguals with diffusion-weighted magnetic resonance images recruited from the community were matched with monolinguals drawn from a pool of 165 individuals in the Alzheimers Disease Neuroimaging Initiative (ADNI) database. White matter integrity was calculated for all participants using fractional anisotropy, axial diffusivity, and radial diffusivity scores. Propensity scores were obtained using white matter measures, sex, age, and education as predictive covariates, and then used in one-to-one matching between language groups, creating a matched sample of 32 participants per group. Matched monolinguals had poorer clinical diagnoses than that predicted by chance from a theoretical null distribution, and poorer cognitive performances than matched bilinguals as measured by scores on the MMSE. The findings support the interpretation that bilingualism acts as a proxy of CR such that monolinguals have poorer clinical and cognitive outcomes than bilinguals for similar levels of white matter integrity even before clinical symptoms appear. The second study examines the role of biomarkers and genetic factors associated with Alzheimer disease in a sample of 641 individuals from the ADNI database. Gradient boosted regression modelling was used to examine the influence of 10 predictive factors on clinical diagnosis in 3 different models. Weighted propensity scores were applied to analyses of white matter integrity and cognitive performance between clinical groups in two models and between language groups in one model. Analyses revealed a strong influence of biomarkers and genetic factors on clinical diagnosis in monolingual participants, but underrepresentation of bilingual participants in the sample limited interpretations of the findings between language groups. The results of the second study indicate that information about biomarkers and genetic factors improves analyses exploring the role of CR on dementia outcomes.
Keyword: ADNI; Aging; Alzheimer's disease; Amyloid beta; APOE; Bilingualism; Bilinguals; Brain health; Cognitive reserve; Dementia; Language; Monolinguals; Tau
URL: http://hdl.handle.net/10315/38767
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6
The Effects of Bilingualism on Memory and Brain Integrity Across the Adult Lifespan
Macbeth, Alessandra Kaitlyn. - : eScholarship, University of California, 2020
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7
Дизайн исследования структуры письменной речи лиц пожилого и старческого возрастов ; Design of Research of Written Speech Structure in Elderly and Senile Age Groups
Khristolubov, A.; Dorogina, O.; Христолюбов, А. А.. - : Издательство Уральского университета, 2020
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8
Active bilingualism delays the onset of mild cognitive impairment
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9
A cross-sectional and longitudinal study on the protective effect of bilingualism against dementia using brain atrophy and cognitive measures.
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10
A Systematic Review on the Possible Relationship Between Bilingualism, Cognitive Decline, and the Onset of Dementia
In: Behavioral Sciences ; Volume 9 ; Issue 7 (2019)
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11
Cognitive Reserve in older adult Bilinguals: Cognitive Control Level ...
Ζήση, Ευαγγελία Χρήστου. - : Aristotle University of Thessaloniki, 2019
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12
The Mental Health Impact of Aphasia: Risk Factors and Moderating Factors
MURTAGH, AOIFE MARIE. - : Trinity College Dublin. School of Psychology. Discipline of Psychology, 2019
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13
Editorial: Intra- and inter-individual variability of executive functions: Determinant and modulating factors in healthy and pathological conditions
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14
Efectos neuroprotectores del bilingüismo contra la demencia. Un estudio de morfometría basada en el voxel
Marin-Marin, Lidón; Costumero, Víctor; Aguirre, Naiara. - : Publicacions de la Universitat Jaume I. Servei de Comunicació i Publicacions, 2019
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15
Editorial: Intra- and Inter-individual Variability of Executive Functions: Determinant and Modulating Factors in Healthy and Pathological Conditions
MacPherson, Sarah E.; Gillebert, Celine R.; Robinson, Gail A.. - : Frontiers Research Foundation, 2019
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16
A diffusion model approach to analyzing performance on the Flanker task: the role of the DLPFC
Soares, Sergio Miguel Pereira; Ong, Gabriel; Abutalebi, J. U.B.I.N.. - : Cambridge University Press, 2018
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17
Biculturalism, Bilingualism, & Executive Function Among U.S. Latinos: Implications for Cognitive Reserve
In: Dissertations (1934 -) (2017)
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18
Cognitive reserve and cognitive performance of patients with focal frontal lesions.
In: Neuropsychologia , 96 pp. 19-28. (2017) (2017)
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19
Bilingualism Across the Adult Life-Span: Age and Language Usage Are Continuous Variables
In: ETD Archive (2016)
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20
КОГНИТИВНЫЙ РЕЗЕРВ КАК ПСИХОЛОГИЧЕСКИЙ И ПСИХОФИЗИОЛОГИЧЕСКИЙ РЕСУРС В ПЕРИОД СТАРЕНИЯ
СТРИЖИЦКАЯ ОЛЬГА ЮРЬЕВНА. - : Федеральное государственное бюджетное образовательное учреждение высшего образования «Санкт-Петербургский государственный университет», 2016
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