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Serum homocysteine and folate concentrations are associated with prevalent age-related hearing loss
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Incidence, persistence, and progression of tinnitus symptoms in older adults : the Blue Mountains hearing study
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43 |
Role of general practitioners in managing age-related hearing loss
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Dietary glycemic load is a predictor of age-related hearing loss in older adults
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Hearing loss impacts on the use of community and informal supports
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Consumption of omega-3 fatty acids and fish and risk of age-related hearing loss
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Identification of different subtypes of auditory neuropathy using electrocochleography
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Abstract:
Currently, the physiological mechanisms underlying auditory neuropathy are unclear, and there are likely to be multiple sites of lesion. A better understanding of the disruption in individual cases may lead to more effective management and device selection. Frequency-specifi c round-window electrocochleography (ECochG) waveforms were used to assess local hair cell, dendritic, and axonal currents generated within the cochlea in 15 subjects with auditory neuropathy (16 ears). These results were compared with electrically evoked auditory brainstem response (EABR) measured after cochlear implantation. The results of this study demonstrate that predominantly two patterns of ECochG waveforms can be identifi ed: (i) a prolonged latency of the hair cell summating potential (SP) waveform with or without residual CAP activity and (ii) a normal latency SP, typically followed by a dendritic potential (DP). We show that seven of eight subjects with a prolonged SP showed a normal EABR waveform, consistent with a presynaptic lesion, whereas six of seven subjects with a normal latency SP showed poor morphology or absent EABR waveforms, consistent with a postsynaptic lesion. We suggest that a presynaptic and postsynaptic type of auditory neuropathy exist, which may have implications for the fi tting of cochlear implants. ; 16 page(s)
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Keyword:
119900 Other Medical and Health Sciences; auditory neuropathy; cochlear implantation; cochlear microphonic; electrocochleography; summating potential
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URL: http://hdl.handle.net/1959.14/130682
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The contribution of Spectral Envelope and Spectral Fine-Structures Cues TOP Lexical Tone Perception in Mandarin
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Hearing Aids for Meniere's Syndrome: Implications of Hearing Fluctuation
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Frequency-specific electrocochleography indicates that presynaptic and postsynaptic mechanisms of auditory neuropathy exist
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52 |
The contribution of family history to hearing loss in an older population
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Correlation between speech perception and electrically-evoked auditory potentials measured in subjects with Auditory Neuropathy after cochlear implantation
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The Fluctuations of symptoms in Menieres Disease and their implications in the fitting of hearing aids
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The Use of cortical auditory evoked potentials to evaluate neural encoding of speech sounds in adults
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Development of a technique to measure asynchronous neural activity in auditory neuropathy subjects
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Ringing cochlear microphonic waveforms in auditory neuropathy : mechanisms and outcome of cochlear implantation
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Ringing cochlear microphonic waveform ini auditory neuropathy subjects : characteristics and outcomes of cochlear implantation
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Determinants of the spectrum of the neural electrical activity at the round window: transmitter release and neural depolarisation
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