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1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans
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Genome-Wide Association Study of Circulating Interleukin 6 Levels Identifies Novel Loci
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In: ISSN: 0964-6906 ; EISSN: 1460-2083 ; Human Molecular Genetics ; https://hal.univ-lorraine.fr/hal-03177225 ; Human Molecular Genetics, Oxford University Press (OUP), 2021, ⟨10.1093/hmg/ddab023⟩ (2021)
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Novel genetic loci associated with hippocampal volume
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In: ISSN: 2041-1723 ; EISSN: 2041-1723 ; Nature Communications ; https://hal.archives-ouvertes.fr/hal-01488337 ; Nature Communications, Nature Publishing Group, 2017, 8, pp.13624. ⟨10.1038/ncomms13624⟩ (2017)
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Novel genetic loci underlying human intracranial volume identified through genome-wide association
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In: ISSN: 1097-6256 ; EISSN: 1546-1726 ; Nature Neuroscience ; https://hal.archives-ouvertes.fr/hal-01382716 ; Nature Neuroscience, Nature Publishing Group, 2016, 19 (12), pp.1569-1582. ⟨10.1038/nn.4398⟩ (2016)
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Common genetic variants influence human subcortical brain structures.
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In: ISSN: 0028-0836 ; EISSN: 1476-4679 ; Nature ; https://hal.archives-ouvertes.fr/hal-01196805 ; Nature, Nature Publishing Group, 2015, 520 (7546), pp.224-9. ⟨10.1038/nature14101⟩ (2015)
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The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data
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Thompson, Paul,; Stein, Jason,; Medland, Sarah; Hibar, Derrek,; Vasquez, Alejandro,; Renteria, Miguel,; Toro, Roberto; Jahanshad, Neda,; Schumann, Gunter; Franke, Barbara; Wright, Margaret; Martin, Nicholas,; Agartz, Ingrid; Alda, Martin; Alhusaini, Saud; Almasy, Laura; Almeida, Jorge; Alpert, Kathryn; Andreasen, Nancy,; Andreassen, Ole,; Apostolova, Liana,; Appel, Katja; Armstrong, Nicola,; Aribisala, Benjamin; Bastin, Mark; Bauer, Michael; Bearden, Carrie,; Bergmann, Ørjan; Binder, Elisabeth; Blangero, John; Bockholt, Henry,; Bøen, Erlend; Bois, Catherine; Boomsma, Dorret; Booth, Tom; Bowman, Ian,; Bralten, Janita; Brouwer, Rachel,; Brunner, Han,; Brohawn, David,; Buckner, Randy,; Buitelaar, Jan; Bulayeva, Kazima,; Bustillo, Juan,; Calhoun, Vince,; Cannon, Dara,; Cantor, Rita; Carless, Melanie,; Caseras, Xavier; Cavalleri, Gianpiero,; Chakravarty, M. Mallar; Chang, Kiki,; Ching, Christopher; Christoforou, Andrea; Cichon, Sven; Clark, Vincent,; Conrod, Patricia; Coppola, Giovanni; Crespo-Facorro, Benedicto; Curran, Joanne,; Czisch, Michael; Deary, Ian; De Geus, Eco; den Braber, Anouk; Delvecchio, Giuseppe; Depondt, Chantal; De Haan, Lieuwe; De Zubicaray, Greig,; Dima, Danai; Dimitrova, Rali; Djurovic, Srdjan; Dong, Hongwei; Donohoe, Gary; Duggirala, Ravindranath; Dyer, Thomas; Ehrlich, Stefan; Ekman, Carl,; Elvsåshagen, Torbjørn; Emsell, Louise; Erk, Susanne; Espeseth, Thomas; Fagerness, Jesen; Fears, Scott; Fedko, Iryna; Fernández, Guillén; Fisher, Simon; Foroud, Tatiana; Fox, Peter; Francks, Clyde; Frangou, Sophia,; Frey, Eva; Frodl, Thomas; Frouin, Vincent; Garavan, Hugh; Giddaluru, Sudheer; Glahn, David,; Godlewska, Beata; Goldstein, Rita; Gollub, Randy; Grabe, Hans,; Grimm, Oliver; Gruber, Oliver; Guadalupe, Tulio; Gur, Raquel,; Gur, Ruben,; Göring, Harald,; Hagenaars, Saskia; Hajek, Tomas; Hall, Geoffrey,; Hall, Jérémy; Hardy, John; Hartman, Catharina; Hass, Johanna; Hatton, Sean,; Haukvik, Unn,; Hegenscheid, Katrin; Heinz, Andreas; Hickie, Ian; Ho, Beng-Choon; Hoehn, David; Hoekstra, Pieter; Hollinshead, Marisa; Holmes, Avram,; Homuth, Georg; Hoogman, Martine; Hong, L,; Hosten, Norbert; Hottenga, Jouke-Jan; Hulshoff Pol, Hilleke,; Hwang, Kristy,; Jack, Clifford,; Jenkinson, Mark; Johnston, Caroline; Jönsson, Erik,; Kahn, Rene; Kasperaviciute, Dalia; Kelly, Sinead,; Kim, Sungeun; Kochunov, Peter,; Koenders, Laura; Krämer, Bernd; Kwok, John,; Lagopoulos, Jim; Laje, Gonzalo; Landén, Mikael; Landman, Bennett,; Lauriello, John; Lawrie, Stephen,; Lee, Phil; Le Hellard, Stephanie; Lemaître, Hervé; Leonardo, Cassandra,; Li, Chiang-shan; Liberg, Benny; Liewald, David,; Liu, Xinmin; Lopez, Lorna; Loth, Eva; Lourdusamy, Anbarasu; Luciano, Michelle; Macciardi, Fabio; Machielsen, Marise,; MacQueen, Glenda,; Malt, Ulrik,; Mandl, René; Manoach, Dara,; Martinot, Jean-Luc; Matarin, Mar; Mather, Karen; Mattheisen, Manuel; Mattingsdal, Morten; Meyer-Lindenberg, Andreas; McDonald, Colm; Mcintosh, Andrew; McMahon, Francis,; Mcmahon, Katie,; Meisenzahl, Eva; Melle, Ingrid; Milaneschi, Yuri; Mohnke, Sebastian; Montgomery, Grant,; Morris, Derek; Moses, Eric,; Mueller, Bryon,; Muñoz Maniega, Susana; Mühleisen, Thomas,; Müller-Myhsok, Bertram; Mwangi, Benson; Nauck, Matthias; Nho, Kwangsik; Nichols, Thomas,; Nilsson, Lars-Göran; Nugent, Allison,; Nyberg, Lars; Olvera, Rene,; Oosterlaan, Jaap; Ophoff, Roel,; Pandolfo, Massimo; Papalampropoulou-Tsiridou, Melina; Papmeyer, Martina; Paus, Tomas; Pausova, Zdenka; Pearlson, Godfrey,; Penninx, Brenda; Peterson, Charles,; Pfennig, Andrea; Phillips, Mary; Pike, G. Bruce; Poline, Jean-Baptiste; Potkin, Steven,; Pütz, Benno; Ramasamy, Adaikalavan; Rasmussen, Jerod; Rietschel, Marcella; Rijpkema, Mark; Risacher, Shannon,; Roffman, Joshua,; Roiz-Santiañez, Roberto; Romanczuk-Seiferth, Nina; Rose, Emma; Royle, Natalie,; Rujescu, Dan; Ryten, Mina; Sachdev, Perminder; Salami, Alireza; Satterthwaite, Theodore,; Savitz, Jonathan; Saykin, Andrew; Scanlon, Cathy; Schmaal, Lianne; Schnack, Hugo,; Schork, Andrew; Schulz, S,; Schür, Remmelt; Seidman, Larry; Shen, Li; Shoemaker, Jody,; Simmons, Andrew; Sisodiya, Sanjay; Smith, Colin; Smoller, Jordan,; Soares, Jair,; Sponheim, Scott,; Sprooten, Emma; Starr, John,; Steen, Vidar; Strakowski, Stephen; Strike, Lachlan; Sussmann, Jessika; Sämann, Philipp,; Teumer, Alexander; Toga, Arthur,; Tordesillas-Gutierrez, Diana; Trabzuni, Daniah; Trost, Sarah; Turner, Jessica; Van Den Heuvel, Martijn,; van der Wee, Nic,; van Eijk, Kristel; Van Erp, Theo,; Van Haren, Neeltje,; van ’t Ent, Dennis; van Tol, Marie-Jose; Valdés Hernández, Maria,; Veltman, Dick,; Versace, Amelia; Völzke, Henry; Walker, Robert; Walter, Henrik; Wang, Lei; Wardlaw, Joanna; Weale, Michael,; Weiner, Michael; Wen, Wei; Westlye, Lars; Whalley, Heather,; Whelan, Christopher,; White, Tonya; Winkler, Anderson,; Wittfeld, Katharina; Woldehawariat, Girma; Wolf, Christiane; Zilles, David; Zwiers, Marcel; Thalamuthu, Anbupalam; Schofield, Peter,; Freimer, Nelson,; Lawrence, Natalia; Drevets, Wayne
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In: ISSN: 1931-7557 ; EISSN: 1931-7565 ; Brain imaging and behavior (Brain Imaging Behav) ; https://hal-pasteur.archives-ouvertes.fr/pasteur-01967166 ; Brain imaging and behavior (Brain Imaging Behav), Secaucus, NJ : Springer, 2014, 8 (2), pp.152-182. ⟨10.1007/s11682-013-9269-5⟩ (2014)
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Abstract:
International audience ; The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) Consortium is a collaborative network of researchers working together on a range of large-scale studies that integrate data from 70 institutions worldwide. Organized into Working Groups that tackle questions in neuroscience, genetics, and medicine, ENIGMA studies have analyzed neuroimaging data from over 12,826 subjects. In addition, data from 12,171 individuals were provided by the CHARGE consortium for replication of findings, in a total of 24,997 subjects. By meta-analyzing results from many sites, ENIGMA has detected factors that affect the brain that no individual site could detect on its own, and that require larger numbers of subjects than any individual neuroimaging study has currently collected. ENIGMA's first project was a genome-wide association study identifying common variants in the genome associated with hippocampal volume or intracranial volume. Continuing work is exploring genetic associations with subcortical volumes (ENIGMA2) and white matter microstructure (ENIGMA-DTI). Working groups also focus on understanding how schizophrenia, bipolar illness, major depression and attention deficit/hyperactivity disorder (ADHD) affect the brain. We review the current progress of the ENIGMA Consortium, along with challenges and unexpected discoveries made on the way.
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Keyword:
[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]; [SDV]Life Sciences [q-bio]
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URL: https://hal-pasteur.archives-ouvertes.fr/pasteur-01967166 https://hal-pasteur.archives-ouvertes.fr/pasteur-01967166/document https://hal-pasteur.archives-ouvertes.fr/pasteur-01967166/file/thompson2014.pdf https://doi.org/10.1007/s11682-013-9269-5
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