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Longitudinal association of intraindividual variability with cognitive decline and dementia: A meta-analysis
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In: Research outputs 2014 to 2021 (2021)
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Abstract:
Objective: Intraindividual variability (IIV)—variance in an individual's cognitive performance—may be associated with subsequent cognitive decline and/or conversion to dementia in older adults. This novel measure of cognition encompasses two main operationalizations: inconsistency (IIV-I) and dispersion (IIV-D), referring to variance within or across tasks, respectively. Each operationalization can also be measured with or without covariates. This meta-analytic study explores the association between IIV and subsequent cognitive outcomes regardless of operational definition and measurement approach. Method: Longitudinal studies (N = 13) that have examined IIVin association with later cognitive decline and/or conversation toMCI/ dementia were analyzed. The effect of IIV operationalization was explored. Additional subgroup analysis of measurement approaches could not be examined due to the limited number of appropriate studies available for inclusion. Results: Meta-analytic estimates suggest IIV is associated with subsequent cognitive decline and/or conversion to MCI/dementia (r =.20, 95% CI [.09,.31]) with no significant difference between the two operationalizations, appears to be associated with subsequent cognitive decline and/or dementia andmay offer a novel indicator of incipient dementia in both clinical and research settings.
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Keyword:
cognitive decline; dementia; Intraindividual variability; Medical Sciences; Medicine and Health Sciences; Neurosciences
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URL: https://doi.org/10.1037/neu0000746 https://ro.ecu.edu.au/ecuworkspost2013/11597
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The Effect of Hearing Aid Use on Cognition in Older Adults: Can We Delay Decline or Even Improve Cognitive Function?
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The Effect of Cochlear Implants on Cognitive Function in Older Adults: Initial Baseline and 18-Month Follow Up Results for a Prospective International Longitudinal Study
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The effect of preclinical Alzheimer's disease on age-related changes in intelligence in cognitively normal older adults
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In: Research outputs 2014 to 2021 (2018)
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Trajectories of irregular word reading ability as a proxy for premorbid intelligence in Alzheimer's disease, mild cognitive impairment, and healthy aging: A longitudinal study
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In: Research outputs 2014 to 2021 (2018)
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The nature and rate of cognitive maturation from late childhood to adulthood
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Preliminary Data on the Effect of Culture on the Assessment of Alzheimer's Disease-Related Verbal Memory Impairment with the International Shopping List Test
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Standardization of pitch range settings in voice acoustic analysis
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Cognitive processing in children using cochlear implants: the relationship between visual memory, attention, and executive functions and developing language skills
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