• Refine your search:
  • 
    Keyword:
    
    • Article (3)
    • Clinical and epidemiological research (3)
    • Concise Report (2)
    • Poster Presentation (2)
    • Supplement (2)
    • ASSOCIATION STUDIES ARTICLES (1)
    • Basic and translational research (1)
    • Oral Presentation (1)
  • 
    Creator / Publisher
  • 
    Year
  • 
    Medium:
    
    • Online (19)
  • 
    Type
  • 
    BLLDB-Access

Search in the Catalogues and Directories

All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Hits 1 – 19 of 19 1 Identification of novel genetic markers associated with clinical phenotypes of systemic sclerosis through a genome-wide association strategy. Gorlova, Olga; Martín, J. E.; Rueda, B.. - : Public Library of Science, 2011 BASE Show details 2 Polymorphisms in the interleukin 4, interleukin 13 and corresponding receptor genes are not associated with systemic sclerosis and do not influence gene expression Broen, J C A; Dieude, P; Vonk, M C. - : British Medical Journal Publishing Group, 2011 BASE Show details 3 Analysis of the influence of PTPN22 gene polymorphisms in systemic sclerosis Diaz-Gallo, LM; Gourh, P; Broen, J. - : BMJ Publishing Group Ltd, 2011 BASE Show details 4 Variants of PBEF predispose to systemic sclerosis and pulmonary arterial hypertension development Broen, J C A; Gourh, P; Vonk, M C. - : British Medical Journal Publishing Group, 2011 BASE Show details 5 A replication study confirms the association of TNFSF4 (OX40L) polymorphisms with systemic sclerosis in a large European cohort Bossini-Castillo, L.; Broen, J.C.A.; Simeon, C.P.. - : B M J Group, 2011 BASE Show details 6 Identification of novel genetic markers associated with clinical phenotypes of systemic sclerosis through a genome-wide association strategy McCarthy, M.I.; Gorlova, O.; Martin, J-E.. - : Public Library of Science, 2011 BASE Show details 7 Identification of Novel Genetic Markers Associated with Clinical Phenotypes of Systemic Sclerosis through a Genome-Wide Association Strategy Gorlova O; Martin JE; Rueda B... In: PLoS Genetics, 14-07-2011 (2011) BASE Show details 8 Analysis of the influence of PTPN22 gene polymorphisms in systemic sclerosis Diaz-Gallo, LM; Gourh, P; Broen, J. - : BMJ Publishing Group Ltd, 2010 BASE Show details 9 Identification of novel genetic markers associated with the clinical phenotypes of systemic sclerosis through a genome wide association strategy Gorlova, O; Martin, J M; Rueda, B. - : BioMed Central, 2010 BASE Show details 10 Analysis of the influence of PTPN22 gene polymorphisms in systemic sclerosis Diaz-Gallo, LM; Gourh, P; Broen, J. - 2010 BASE Show details 11 Variants of PBEF predispose to systemic sclerosis and pulmonary arterial hypertension development Broen, JCA; Gourh, P; Vonk, M C. - : BioMed Central, 2010 BASE Show details 12 Polymorphisms in the interleukin 4, interleukin 13 and corresponding receptor genes are not associated with Systemic Sclerosis and do not influence gene expression Broen, JCA; Dieude, P; Vonk, M C. - : BioMed Central, 2010 BASE Show details 13 The STAT4 gene influences the genetic predisposition to systemic sclerosis phenotype Rueda, B.; Broen, J.; Simeon, C.. - : Oxford University Press, 2009 BASE Show details 14 The STAT4 gene influences the genetic predisposition to systemic sclerosis phenotype Rueda, B.; Broen, J.; Simeon, C.; Hesselstrand, R.; Diaz, B.; Suárez, H.; Ortego-Centeno, N.; Riemekasten, G.; Fonollosa, V.; Vonk, M.C.; van den Hoogen, F.H.J.; Sanchez-Román, J.; Aguirre-Zamorano, M.A.; García-Portales, R.; Pros, A.; Camps, M.T.; Gonzalez-Gay, M.A.; Coenen, M.J.H.; Airo, P.; Beretta, L.; Scorza, R.; van Laar, J.; Gonzalez-Escribano, M.F.; Nelson, J.L.; Radstake, T.R.D.J.; Martin, J.. - : Oxford University Press, 2009 Abstract: The aim of this study was to investigate the possible role of STAT4 gene in the genetic predisposition to systemic sclerosis (SSc) susceptibility or clinical phenotype. A total of 1317 SSc patients [896 with limited cutaneous SSc (lcSSc) and 421 with diffuse cutaneous SSc (dcSSc)] and 3113 healthy controls, from an initial case–control set of Spanish Caucasian ancestry and five independent cohorts of European ancestry (The Netherlands, Germany, Sweden, Italy and USA), were included in the study. The rs7574865 polymorphism was selected as STAT4 genetic marker. We observed that the rs7574865 T allele was significantly associated with susceptibility to lcSSc in the Spanish population [ P = 1.9 × 10−5 odds ratio (OR) 1.61 95% confidence intervals (CI) 1.29–1.99], but not with dcSSc ( P = 0.41 OR 0.84 95% CI 0.59–1.21). Additionally, a dosage effect was observed showing individuals with rs7574865 TT genotype higher risk for lcSSc (OR 3.34, P = 1.02 × 10−7 95% CI 2.11–5.31). The association of the rs7574865 T allele with lcSSc was confirmed in all the replication cohorts with different effect sizes (OR ranging between 1.15 and 1.86), as well as the lack of association of STAT4 with dcSSc. A meta-analysis to test the overall effect of the rs7574865 polymorphism showed a strong risk effect of the T allele for lcSSc susceptibility (pooled OR 1.54 95% CI 1.36–1.74; P < 0.0001). Our data show a strong and reproducible association of the STAT4 gene with the genetic predisposition to lcSSc suggesting that this gene seems to be one of the genetic markers influencing SSc phenotype. Keyword: ASSOCIATION STUDIES ARTICLES URL: http://hmg.oxfordjournals.org/cgi/content/short/18/11/2071 https://doi.org/10.1093/hmg/ddp119 BASE Hide details 15 A large multicentre analysis of CTGF -945 promoter polymorphism does not confirm association with systemic sclerosis susceptibility or phenotype Rueda, B; Simeon, C; Hesselstrand, R. - : BMJ Publishing Group Ltd, 2009 BASE Show details 16 The interleukin 23 receptor gene does not confer risk to systemic sclerosis and is not associated with systemic sclerosis disease phenotype Rueda, B; Broen, J; Torres, O. - : BMJ Publishing Group Ltd, 2009 BASE Show details 17 The Interleukin 23 Receptor gene does not confer risk to systemic sclerosis and is not associated with SSc disease phenotype Rueda, B; Broen, J; Torres, O. - : BMJ Publishing Group Ltd, 2008 BASE Show details 18 A large multicenter analysis of CTGF -945 promoter polymorphism does not confirm association with Systemic Sclerosis susceptibility or phenotype Rueda, B; Simeon, C; Hesselstrand, R. - : BMJ Publishing Group Ltd, 2008 BASE Show details 19 A large multicenter analysis of CTGF -945 promoter polymorphism does not confirm association with Systemic Sclerosis susceptibility or phenotype Rueda, B; Simeon, C; Hesselstrand, R. - 2008 BASE Show details

Mobile view All Catalogues UB Frankfurt Linguistik 0 IDS Mannheim 0 OLC Linguistik 0 UB Frankfurt Retrokatalog 0 DNB Subject Category Language 0 Institut für Empirische Sprachwissenschaft 0 Leibniz-Centre General Linguistics (ZAS) 0 Bibliographies BLLDB 0 BDSL 0 IDS Bibliografie zur deutschen Grammatik 0 IDS Bibliografie zur Gesprächsforschung 0 IDS Konnektoren im Deutschen 0 IDS Präpositionen im Deutschen 0 IDS OBELEX meta 0 MPI-SHH Linguistics Collection 0 MPI for Psycholinguistics 0 Linked Open Data catalogues Annohub 0 Online resources Link directory 0 Journal directory 0 Database directory 0 Dictionary directory 0 Open access documents BASE 19 Linguistik-Repository 0 IDS Publikationsserver 0 Online dissertations 0 Language Description Heritage 0