| 1 |
Predictive factors of speech intelligibility following subthalamic nucleus stimulation in consecutive patients with Parkinson's disease
|
|
|
|
In: Movement Disorders , 29 (4) 532 - 538. (2014) (2014)
|
|
BASE
|
|
Show details
|
|
|
| 2 |
Effects of deep brain stimulation on speech in patients with Parkinson’s disease and dystonia
|
|
|
|
In: Doctoral thesis, UCL (University College London). (2011)
|
|
BASE
|
|
Show details
|
|
|
| 3 |
Treatment of dysarthria following subthalamic nucleus deep brain stimulation for Parkinson's disease.
|
|
|
|
In: Mov Disord , 26 (13) 2434 - 2436. (2011) (2011)
|
|
BASE
|
|
Show details
|
|
|
| 4 |
Effects of medication and subthalamic nucleus deep brain stimulation on tongue movements in speakers with Parkinson's disease using electropalatography: A pilot study
|
|
|
|
In: CLIN LINGUIST PHONET , 25 (3) 210 - 230. (2011) (2011)
|
|
BASE
|
|
Show details
|
|
|
| 5 |
Functional Magnetic Resonance Imaging Exploration of Combined Hand and Speech Movements in Parkinson's Disease
|
|
|
|
In: MOVEMENT DISORD , 26 (12) 2212 - 2219. (2011) (2011)
|
|
BASE
|
|
Show details
|
|
|
| 6 |
Effects of medication and subthalamic nucleus deep brain stimulation on tongue movements in speakers with Parkinson's disease using electropalatography: A pilot study
|
|
|
|
BASE
|
|
Show details
|
|
|
| 7 |
Delivering the Lee Silverman Voice Treatment (LSVT) by web camera: a feasibility study
|
|
|
|
BASE
|
|
Show details
|
|
|
| 8 |
Speech in Parkinson's disease following subthalamic nucleus deep brain stimulation: Preliminary results
|
|
|
|
In: JOURNAL OF MEDICAL SPEECH-LANGUAGE PATHOLOGY , 14 (4) 309 - 315. (2006) (2006)
|
|
Abstract:
Impairment of speech can affect the majority of patients with Parkinson's disease (PD). Deep brain stimulation of the subthalamic nucleus (STN-DBS) is an effective treatment for the improvement of limb movements, but its effect on speech is less predictable. This study aims to compare the effects of STN-DBS versus the effects of medical (drug) treatment alone on speech and limb movement over 1 year. Sixteen consecutive patients with PD, who were part of a larger trial, were randomized in two groups, either surgical treatment (N = 8) with bilateral STN-DBS or medical treatment (N = 8). Both groups were assessed in the "on and off" medication states, at baseline and at 1 year, using a speech evaluation protocol and the motor part of the Unified Parkinson's Disease Rating Scale (UPDRS-III). The group that received STN-DBS was also assessed in the "on and off" stimulation states. The speech evaluation consisted of recordings of sustained phonation, sentence reading, and 1 minute of monologue. The STN-DBS group in the "on medication and on stimulation" state showed an improvement of the UPDRS-III score. Stimulation and medication also increased significantly the intensity of sustained phonation and the mean of long-term average spectra of the read sentences and the monologue. The sentence intelligibility scores did not change significantly in either group, with the STN-DBS patients showing a wide variability. All acoustical measures of speech for the medical group showed a small and nonsignificant deterioration over 1 year. This is the first study to compare the effects of medical and STN-DBS treatment on speech and limb movement in PD over a year. The different effects of STN-DBS and medication on speech and limb movement warrant further investigation.
|
|
Keyword:
AVERAGE SPECTRUM; BREATHINESS; DYSARTHRIA; DYSPHONIA; INTELLIGIBILITY; PATIENT; SIGNAL; VOICE
|
|
URL: http://discovery.ucl.ac.uk/112775/
|
|
BASE
|
|
Hide details
|
|
|
| 9 |
Treatments for dysarthria in Parkinson's disease
|
|
|
|
In: LANCET NEUROL , 3 (9) 547 - 556. (2004) (2004)
|
|
BASE
|
|
Show details
|
|
|
|
|
