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Primary progressive aphasia and the FTD-MND spectrum disorders: clinical, pathological, and neuroimaging correlates ...
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Primary progressive aphasia and the FTD-MND spectrum disorders: clinical, pathological, and neuroimaging correlates ...
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Vinceti, Giulia; Olney, Nicholas; Mandelli, Maria Luisa; Spina, Salvatore; H. Isabel Hubbard; Santos-Santos, Miguel A.; Watson, Christa; Miller, Zachary A.; Lomen-Hoerth, Catherine; Nichelli, Paolo; Miller, Bruce L.; Grinberg, Lea T.; Seeley, William W.; Gorno-Tempini, Maria Luisa. - : Taylor & Francis, 2020
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Abstract:
Objective: Behavioral variant frontotemporal dementia (bvFTD), is commonly considered the cognitive presentation of the frontotemporal dementia-motor neuron disease (FTD-MND) spectrum disorder. We evaluated the prevalence of primary progressive aphasia in a series of pathologically confirmed cases of FTD-MND spectrum. Methods: Pathologically confirmed cases of frontotemporal lobar degeneration-motor neuron disease (FTLD-MND) were obtained from the UCSF brain bank. Cases were analyzed for presence of language impairment via retrospective chart review of research visits that include neurologic exam, in-depth cognitive testing and magnetic resonance imaging (MRI) imaging. Forty one cases were included. Thirty two were diagnosed with FTD-MND, while nine cases were diagnosed as MND-only from clinical evaluation. Results: Ten FTLD-MND cases (31%) presented with prominent or isolated language involvement consistent with a diagnosis of primary progressive aphasia (PPA), which we called progressive aphasia with motor ...
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Keyword:
FOS Sociology; Medicine; Neuroscience; Sociology
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URL: https://tandf.figshare.com/articles/Primary_progressive_aphasia_and_the_FTD-MND_spectrum_disorders_clinical_pathological_and_neuroimaging_correlates/7615766/2
https://dx.doi.org/10.6084/m9.figshare.7615766.v2
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Cortical developmental abnormalities in logopenic variant primary progressive aphasia with dyslexia.
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In: Brain communications, vol 1, iss 1 (2019)
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Cortical developmental abnormalities in logopenic variant primary progressive aphasia with dyslexia.
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In: Brain communications, vol 1, iss 1 (2019)
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Primary progressive aphasia and the FTD-MND spectrum disorders: clinical, pathological, and neuroimaging correlates ...
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Primary progressive aphasia and the FTD-MND spectrum disorders: clinical, pathological, and neuroimaging correlates
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Astrocytic Tau Deposition Is Frequent in Typical and Atypical Alzheimer Disease Presentations
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In: J Neuropathol Exp Neurol (2019)
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Cortical developmental abnormalities in logopenic variant primary progressive aphasia with dyslexia
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In: Brain Commun (2019)
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Patient-Tailored, Connectivity-Based Forecasts of Spreading Brain Atrophy
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Cerebrospinal fluid biomarkers predict frontotemporal dementia trajectory.
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In: Annals of clinical and translational neurology, vol 5, iss 10 (2018)
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Cerebrospinal fluid biomarkers predict frontotemporal dementia trajectory.
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In: Annals of clinical and translational neurology, vol 5, iss 10 (2018)
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Prevalence of Mathematical and Visuospatial Learning Disabilities in Patients With Posterior Cortical Atrophy
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Rates Of Amyloid Imaging Positivity In Patients With Primary Progressive Aphasia
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Globular glial tauopathy presenting as non-fluent/agrammatic variant primary progressive aphasia with chorea
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Typical and atypical pathology in primary progressive aphasia variants
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Increased prevalence of autoimmune disease within C9 and FTD/MND cohorts: Completing the picture.
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In: Neurology(R) neuroimmunology & neuroinflammation, vol 3, iss 6 (2016)
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Increased prevalence of autoimmune disease within C9 and FTD/MND cohorts: Completing the picture.
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In: Neurology(R) neuroimmunology & neuroinflammation, vol 3, iss 6 (2016)
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Cross-sectional and longitudinal features of non-fluent/agrammatic primary progressive aphasia with underlying corticobasal degeneration or progressive supranuclear palsy pathology
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Criminal behavior in frontotemporal dementia and Alzheimer disease.
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In: JAMA neurology, vol 72, iss 3 (2015)
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Criminal behavior in frontotemporal dementia and Alzheimer disease.
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In: JAMA neurology, vol 72, iss 3 (2015)
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